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The map label for this gene is ruvB [H]

Identifier: 237813765

GI number: 237813765

Start: 3428012

End: 3429082

Strand: Direct

Name: ruvB [H]

Synonym: GBP346_A3542

Alternate gene names: 237813765

Gene position: 3428012-3429082 (Clockwise)

Preceding gene: 237813764

Following gene: 237813766

Centisome position: 83.64

GC content: 69.09

Gene sequence:

>1071_bases
ATGATCGAAACCGACAAACTCGCCGCCGAGCGGATCATTGCCGCCACGCCCGCGTCTTCGCACGAAGAGGCTTTCGAACG
CGCGCTGCGCCCGCGCCAGCTCGACGAATACGTCGGCCAGGAGAAGGTGCGCGATCAGCTCGAAATCTTCATCGAAGCCG
CGAAGCGCCGCTCCGAAGCGCTCGACCACGTGCTGCTGTTCGGCCCGCCCGGCCTCGGCAAGACGACGCTCGCGCACATC
ATCGCGCGCGAAATGGGCGTGAACCTGCGCCAGACGTCCGGCCCCGTGCTCGAGCGCGCGGGCGACCTCGCCGCGCTGCT
CACGAACCTCGAAGCGAACGACGTCCTCTTCATCGACGAGATCCACCGCCTGTCGCCCGTCGTCGAGGAAATCCTGTATC
CGGCGCTCGAGGATTACCAGATCGACATCATGATCGGCGAAGGGCCAGCCGCGCGCAGCGTGAAGCTCGACCTGCAGCCG
TTCACGCTCGTCGGCGCGACGACGCGCGCGGGCATGCTGACCAATCCGCTGCGCGACCGCTTCGGCATCGTCGCGCGGCT
CGAGTTCTACGACGCCGAGCAGTTGTCGCGCATCGTGCGCCGCTCGGCCGCGCTGCTGAACGCGCAGATCGATCCGGCGG
GCGCGCTCGAGATCGCGAAGCGCTCGCGCGGCACGCCGCGGATCGCGAACCGCCTGCTGCGCCGCGTGCGCGACTACGCG
GAAGTGAAGGCGGACGGCAACATCACCGCGGCCGTCGCGGACGCCGCGCTCGCGATGCTCGACGTCGATCCGGTCGGCTT
CGACCTGATGGACCGCAAGCTGCTCGAGGCGATCCTGCACAAGTTCGACGGCGGGCCGGTCGGCGTCGACAACCTCGCCG
CCGCGATCGGCGAGGAGCGCGACACGATCGAGGACGTGCTCGAGCCGTACCTGATTCAGCAGGGCTTCTTGCAGCGCACG
CCGCGCGGCCGCGTCGCGACGCTCCTCACGTACCGGCATTTCGGTCTCTCCGCGCCCGACGCCGCGAACCCCGTGCGCAA
TCTCTGGGACACGCCCGACGCCGAGTGCTGA

Upstream 100 bases:

>100_bases
ACGGCGCGTCGTCGAAGACAGCTTCGCACGCCGGGCGCCGGGCCGCGACTCGGCCGTTCGGCCAGGTTGGCCGGGGCACG
CCGCGCGGTACAATGGCCGC

Downstream 100 bases:

>100_bases
CGCCCCCCACCCCGACGAGCCGCTCATGTCCGCCCCGCTTCACGACCGCCCCGCCCGCTCGCCGCTCGGACATCCGTTCG
TCGAACGCGTGCGGGCGCGC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEALDHVLLFGPPGLGKTTLAHI
IAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQP
FTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYA
EVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGFLQRT
PRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC

Sequences:

>Translated_356_residues
MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEALDHVLLFGPPGLGKTTLAHI
IAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQP
FTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYA
EVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGFLQRT
PRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC
>Mature_356_residues
MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEALDHVLLFGPPGLGKTTLAHI
IAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQP
FTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYA
EVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGFLQRT
PRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=340, Percent_Identity=70.8823529411765, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 39223; Mature: 39223

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEA
CCCCHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDE
HCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHH
IHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDR
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCHHHHHHHHH
FGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYA
HCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
EVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEER
HHCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCH
DTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEA
CCCCHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDE
HCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHH
IHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDR
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCHHHHHHHHH
FGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYA
HCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
EVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEER
HHCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCH
DTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA