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The map label for this gene is pheA [H]

Identifier: 237813298

GI number: 237813298

Start: 2980712

End: 2981794

Strand: Reverse

Name: pheA [H]

Synonym: GBP346_A3065

Alternate gene names: 237813298

Gene position: 2981794-2980712 (Counterclockwise)

Preceding gene: 237813299

Following gene: 237813297

Centisome position: 72.75

GC content: 67.59

Gene sequence:

>1083_bases
ATGGACGACGAACTCAATTCCCGCCTGAAGCCTCTGCGCGAGCGCATCGACGCGATCGACACGCAACTGATCGCGCTGCT
GAATCAGCGCGCGGCGGTCGCGCTCGAGGTCGGCGAGGTCAAGAAGCACTTCAACGCGCCCGTGTTCCGGCCGGAGCGCG
AGCAGCAGGTGATCGCGCGCTTGCAGGACATGAGCGCCGGGCCGCTCGCGAGCGAGCACATCAGCGCGATCTGGCGCGAG
ATCATGGCGGCGAGCCGCGATCTCGAGCAGACGATACACGTCGCGTTCCTCGGGCCCGTCGGCACCTATAGCGAACAGGC
GATGTTCGACTACTTCGGCCAATCGATCGAGGGGCTGCCTTGCCCGTCGATCGACGAGGTGTTCCGCTCGGTCGAGGCGG
GCGCCGCGACGTTCGGCGTCGTGCCGGTCGAGAATTCGTCGGAAGGCGCGGTGTCGCGCACGCTCGATCTGCTGCTGCAT
ACGCAGCTTCTGATCGGCGGCGAGCTGTCGCTGCCGATTCATCACAATCTGCTCACGCAAACAGGCAAGCTCGACGGCGT
GAAGCGCGTGTGCGCGCATGCGCAGGCGCTCGCGCAGTGCCAGCAATGGCTCGCGTCGAACGCGCCGCATCTCGAGCGGC
AGGCGGTCGCGAGCAACGCGGAAGCCGCGCGGCTCGCGGCCGACGACGCGACTGTCGCCGCGATCGCGGGCGACCGCGCG
GCGACGCACTACGGGCTGCAGATCGCCTATGCGCTGATCCAGGACGATCCGCACAACCGCACGCGCTTCGCGGTGATCGG
CCAGGAGCCGGCGGGGCCGAGCGGGCATGACCAGACCTCGCTCATCGTGTCGGTGAAGAACGAGCCGGGCGCGGTGTTCA
AGCTGCTCGAGCCGCTTGCACGGCACGGCGTGTCGATGACGCGCTTCGAGTCGCGCCCGGCGCGGGTCGGCACGTGGGAG
TATTACTTCTACATCGACATCGAAGGGCATCGCGACGACGCCGCTGTCCAGGGTGCGCTCGCGGAGCTTGGCAGGAAGGC
GGCTTTTCTGAAGATTCTCGGTTCGTATCCGCGCGCGCGGTGA

Upstream 100 bases:

>100_bases
GTGCCGCTCGCGGGCGTGCAGGCGCTCGTCGAGTACATGAAGGATTTCGAGCGGCGCTGCGCGTGACGCGCGCCGCTCCT
TACGCATTGTTGGTCAAGTC

Downstream 100 bases:

>100_bases
CGCGCGGCGCGCCGGTGCGGCCGCATCCGCCGCATCGGTCGATGCGGCGCCCGGTGCGGGCGGCGGTGCCCGCCGGCGCG
TGACGGCGAGCCTTCGCGTC

Product: chorismate mutase/prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MDDELNSRLKPLRERIDAIDTQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIARLQDMSAGPLASEHISAIWRE
IMAASRDLEQTIHVAFLGPVGTYSEQAMFDYFGQSIEGLPCPSIDEVFRSVEAGAATFGVVPVENSSEGAVSRTLDLLLH
TQLLIGGELSLPIHHNLLTQTGKLDGVKRVCAHAQALAQCQQWLASNAPHLERQAVASNAEAARLAADDATVAAIAGDRA
ATHYGLQIAYALIQDDPHNRTRFAVIGQEPAGPSGHDQTSLIVSVKNEPGAVFKLLEPLARHGVSMTRFESRPARVGTWE
YYFYIDIEGHRDDAAVQGALAELGRKAAFLKILGSYPRAR

Sequences:

>Translated_360_residues
MDDELNSRLKPLRERIDAIDTQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIARLQDMSAGPLASEHISAIWRE
IMAASRDLEQTIHVAFLGPVGTYSEQAMFDYFGQSIEGLPCPSIDEVFRSVEAGAATFGVVPVENSSEGAVSRTLDLLLH
TQLLIGGELSLPIHHNLLTQTGKLDGVKRVCAHAQALAQCQQWLASNAPHLERQAVASNAEAARLAADDATVAAIAGDRA
ATHYGLQIAYALIQDDPHNRTRFAVIGQEPAGPSGHDQTSLIVSVKNEPGAVFKLLEPLARHGVSMTRFESRPARVGTWE
YYFYIDIEGHRDDAAVQGALAELGRKAAFLKILGSYPRAR
>Mature_360_residues
MDDELNSRLKPLRERIDAIDTQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIARLQDMSAGPLASEHISAIWRE
IMAASRDLEQTIHVAFLGPVGTYSEQAMFDYFGQSIEGLPCPSIDEVFRSVEAGAATFGVVPVENSSEGAVSRTLDLLLH
TQLLIGGELSLPIHHNLLTQTGKLDGVKRVCAHAQALAQCQQWLASNAPHLERQAVASNAEAARLAADDATVAAIAGDRA
ATHYGLQIAYALIQDDPHNRTRFAVIGQEPAGPSGHDQTSLIVSVKNEPGAVFKLLEPLARHGVSMTRFESRPARVGTWE
YYFYIDIEGHRDDAAVQGALAELGRKAAFLKILGSYPRAR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=372, Percent_Identity=34.9462365591398, Blast_Score=195, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324013, Length=333, Percent_Identity=25.8258258258258, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 39235; Mature: 39235

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDELNSRLKPLRERIDAIDTQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCCCCCCHHHHHHHH
LQDMSAGPLASEHISAIWREIMAASRDLEQTIHVAFLGPVGTYSEQAMFDYFGQSIEGLP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCC
CPSIDEVFRSVEAGAATFGVVPVENSSEGAVSRTLDLLLHTQLLIGGELSLPIHHNLLTQ
CCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
TGKLDGVKRVCAHAQALAQCQQWLASNAPHLERQAVASNAEAARLAADDATVAAIAGDRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHEECCCCEEEEEECCCH
ATHYGLQIAYALIQDDPHNRTRFAVIGQEPAGPSGHDQTSLIVSVKNEPGAVFKLLEPLA
HHHHHHHHEEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
RHGVSMTRFESRPARVGTWEYYFYIDIEGHRDDAAVQGALAELGRKAAFLKILGSYPRAR
HCCCEEEHHCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDDELNSRLKPLRERIDAIDTQLIALLNQRAAVALEVGEVKKHFNAPVFRPEREQQVIAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCCCCCCHHHHHHHH
LQDMSAGPLASEHISAIWREIMAASRDLEQTIHVAFLGPVGTYSEQAMFDYFGQSIEGLP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCCCCC
CPSIDEVFRSVEAGAATFGVVPVENSSEGAVSRTLDLLLHTQLLIGGELSLPIHHNLLTQ
CCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
TGKLDGVKRVCAHAQALAQCQQWLASNAPHLERQAVASNAEAARLAADDATVAAIAGDRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHEECCCCEEEEEECCCH
ATHYGLQIAYALIQDDPHNRTRFAVIGQEPAGPSGHDQTSLIVSVKNEPGAVFKLLEPLA
HHHHHHHHEEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHH
RHGVSMTRFESRPARVGTWEYYFYIDIEGHRDDAAVQGALAELGRKAAFLKILGSYPRAR
HCCCEEEHHCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]