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The map label for this gene is serC [H]

Identifier: 237813299

GI number: 237813299

Start: 2981829

End: 2983007

Strand: Reverse

Name: serC [H]

Synonym: GBP346_A3066

Alternate gene names: 237813299

Gene position: 2983007-2981829 (Counterclockwise)

Preceding gene: 237813300

Following gene: 237813298

Centisome position: 72.78

GC content: 64.29

Gene sequence:

>1179_bases
ATGGCCGTTTGCGCGACAGCGCAAGCGGCCATTTCCTTTTCCCGCGCGGCATTCGGCCGGTTCGAAGCGGCCGGGTCCCT
TCCGAGGTTTTTCACGATGCGCGTCTTTAATTTCTCCGCCGGCCCCGCGGCGATGCCCGAGGAAGTGCTGCGCCAGGCGG
CCGCCGAAATGCTCGACTGGAACGGCAGCGGCATGAGCGTGATGGAAATGAGCCATCGCGGCAAGGAATTCATGTCGATT
CACGAGGCCGCGCTTGCCGACCTGCGCGAATTGCTCGGTGTGCCCGCGAACTACCGGATCCTGTTCCTGCAGGGCGGGGG
GATCGCCGAGAATGCGATCGTGCCGATGAACCTGCTCGGCTCGCGCACGACCGCCGATTTCGTCATCACGGGCTCGTGGT
CGCAGAAATCGTTCAACGAGGCGAAGAAGTACTGCGTGCCGCATCTGGCCGCGACGGGCAAGACGGACGCGGGCTTCACG
CGCGTGCCGGCGTTCTCCGAATGGCGGATGTCGGACGATCCGGCGTACGTGCACCTGTGCACGAACGAGACGATCGACGG
CGTCGAGACGTTCGACATCCCCGATCTCGGCAACGTGCCGCTCGTCGCCGACGTGTCGTCGCACATCCTGTCGCGTCCGA
TCGAGATCGAGAAGTACGGCGCGATCTTCGGCGGCGCGCAGAAGAACATCGGGATGGCGGGCGTGACGCTCGTGATCGTG
CGCGAGGATCTGCTCGATCGCGCGCTGTCGATCTGCCCGTCGGCGTTCGAATGGAAGACGGTCGCGCTCAACAATTCGCT
CTACAACACGCCGCCCACCTATGCGATCTACATCGCGGGCCTCGTGTTCAAGTGGCTGAAGGCGCAGGGCGGCCTGGCCG
CGATCGAGGCGCGCAACATCGAAAAATCGAAGCTGCTGTACGACGCGATCGACGCGAGCGGCTTCTATCTGAACAAGGTC
GAGAAGCCGGCGCGTTCGCGGATGAACGTGCCGTTCTTCCTCGCCGACGAATCGCGCAACGAAGACTTCCTTGCCGGCGC
AAAAGAGCGCGGGCTGCTGCAGTTGAAGGGCCACAAGTCCGTCGGCGGCATGCGGGCGTCGATCTACAACGCGGTGCCGC
TCGCGGGCGTGCAGGCGCTCGTCGAGTACATGAAGGATTTCGAGCGGCGCTGCGCGTGA

Upstream 100 bases:

>100_bases
CGGCGGTCAAGCCGGGCAAGTAAGCCGCATCGGCTGAGGCCCGCCGGCCGGGGCGACGTGCGTCGCCCGTGTTTGGCGGG
TTCATCAGGACAGTGCGATA

Downstream 100 bases:

>100_bases
CGCGCGCCGCTCCTTACGCATTGTTGGTCAAGTCATGGACGACGAACTCAATTCCCGCCTGAAGCCTCTGCGCGAGCGCA
TCGACGCGATCGACACGCAA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MAVCATAQAAISFSRAAFGRFEAAGSLPRFFTMRVFNFSAGPAAMPEEVLRQAAAEMLDWNGSGMSVMEMSHRGKEFMSI
HEAALADLRELLGVPANYRILFLQGGGIAENAIVPMNLLGSRTTADFVITGSWSQKSFNEAKKYCVPHLAATGKTDAGFT
RVPAFSEWRMSDDPAYVHLCTNETIDGVETFDIPDLGNVPLVADVSSHILSRPIEIEKYGAIFGGAQKNIGMAGVTLVIV
REDLLDRALSICPSAFEWKTVALNNSLYNTPPTYAIYIAGLVFKWLKAQGGLAAIEARNIEKSKLLYDAIDASGFYLNKV
EKPARSRMNVPFFLADESRNEDFLAGAKERGLLQLKGHKSVGGMRASIYNAVPLAGVQALVEYMKDFERRCA

Sequences:

>Translated_392_residues
MAVCATAQAAISFSRAAFGRFEAAGSLPRFFTMRVFNFSAGPAAMPEEVLRQAAAEMLDWNGSGMSVMEMSHRGKEFMSI
HEAALADLRELLGVPANYRILFLQGGGIAENAIVPMNLLGSRTTADFVITGSWSQKSFNEAKKYCVPHLAATGKTDAGFT
RVPAFSEWRMSDDPAYVHLCTNETIDGVETFDIPDLGNVPLVADVSSHILSRPIEIEKYGAIFGGAQKNIGMAGVTLVIV
REDLLDRALSICPSAFEWKTVALNNSLYNTPPTYAIYIAGLVFKWLKAQGGLAAIEARNIEKSKLLYDAIDASGFYLNKV
EKPARSRMNVPFFLADESRNEDFLAGAKERGLLQLKGHKSVGGMRASIYNAVPLAGVQALVEYMKDFERRCA
>Mature_391_residues
AVCATAQAAISFSRAAFGRFEAAGSLPRFFTMRVFNFSAGPAAMPEEVLRQAAAEMLDWNGSGMSVMEMSHRGKEFMSIH
EAALADLRELLGVPANYRILFLQGGGIAENAIVPMNLLGSRTTADFVITGSWSQKSFNEAKKYCVPHLAATGKTDAGFTR
VPAFSEWRMSDDPAYVHLCTNETIDGVETFDIPDLGNVPLVADVSSHILSRPIEIEKYGAIFGGAQKNIGMAGVTLVIVR
EDLLDRALSICPSAFEWKTVALNNSLYNTPPTYAIYIAGLVFKWLKAQGGLAAIEARNIEKSKLLYDAIDASGFYLNKVE
KPARSRMNVPFFLADESRNEDFLAGAKERGLLQLKGHKSVGGMRASIYNAVPLAGVQALVEYMKDFERRCA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.6454293628809, Blast_Score=340, Evalue=1e-93,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=43.1372549019608, Blast_Score=290, Evalue=1e-78,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=54.7486033519553, Blast_Score=407, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=46.9613259668508, Blast_Score=342, Evalue=3e-94,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=41.7098445595855, Blast_Score=282, Evalue=5e-77,
Organism=Drosophila melanogaster, GI21356589, Length=367, Percent_Identity=49.3188010899183, Blast_Score=363, Evalue=1e-100,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 42762; Mature: 42630

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVCATAQAAISFSRAAFGRFEAAGSLPRFFTMRVFNFSAGPAAMPEEVLRQAAAEMLDW
CCEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCC
NGSGMSVMEMSHRGKEFMSIHEAALADLRELLGVPANYRILFLQGGGIAENAIVPMNLLG
CCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEECHHHHC
SRTTADFVITGSWSQKSFNEAKKYCVPHLAATGKTDAGFTRVPAFSEWRMSDDPAYVHLC
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCEEEEE
TNETIDGVETFDIPDLGNVPLVADVSSHILSRPIEIEKYGAIFGGAQKNIGMAGVTLVIV
CCCCCCCCEEECCCCCCCCCEEHHHHHHHHHCCCCEEHHCCEECCCCCCCCCCCEEEEEE
REDLLDRALSICPSAFEWKTVALNNSLYNTPPTYAIYIAGLVFKWLKAQGGLAAIEARNI
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCC
EKSKLLYDAIDASGFYLNKVEKPARSRMNVPFFLADESRNEDFLAGAKERGLLQLKGHKS
CHHHHHHHHHCCCCEEHHHHCCHHHHCCCCCEEEECCCCCCHHHCCCCCCCEEEEECCCC
VGGMRASIYNAVPLAGVQALVEYMKDFERRCA
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVCATAQAAISFSRAAFGRFEAAGSLPRFFTMRVFNFSAGPAAMPEEVLRQAAAEMLDW
CEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCC
NGSGMSVMEMSHRGKEFMSIHEAALADLRELLGVPANYRILFLQGGGIAENAIVPMNLLG
CCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEECHHHHC
SRTTADFVITGSWSQKSFNEAKKYCVPHLAATGKTDAGFTRVPAFSEWRMSDDPAYVHLC
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCEEEEE
TNETIDGVETFDIPDLGNVPLVADVSSHILSRPIEIEKYGAIFGGAQKNIGMAGVTLVIV
CCCCCCCCEEECCCCCCCCCEEHHHHHHHHHCCCCEEHHCCEECCCCCCCCCCCEEEEEE
REDLLDRALSICPSAFEWKTVALNNSLYNTPPTYAIYIAGLVFKWLKAQGGLAAIEARNI
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCC
EKSKLLYDAIDASGFYLNKVEKPARSRMNVPFFLADESRNEDFLAGAKERGLLQLKGHKS
CHHHHHHHHHCCCCEEHHHHCCHHHHCCCCCEEEECCCCCCHHHCCCCCCCEEEEECCCC
VGGMRASIYNAVPLAGVQALVEYMKDFERRCA
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA