| Definition | Burkholderia pseudomallei MSHR346 chromosome I, complete genome. |
|---|---|
| Accession | NC_012695 |
| Length | 4,098,576 |
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The map label for this gene is comA [H]
Identifier: 237813001
GI number: 237813001
Start: 2688246
End: 2690816
Strand: Reverse
Name: comA [H]
Synonym: GBP346_A2761
Alternate gene names: 237813001
Gene position: 2690816-2688246 (Counterclockwise)
Preceding gene: 237813002
Following gene: 237813000
Centisome position: 65.65
GC content: 76.16
Gene sequence:
>2571_bases ATGGACATGCGCCGCTCGGGCGGCGCGCAAGGCGGAGGCGCGATGCGGGCGAAGTGCGGCGCGTTCGCGCTCGGCGTGGT CGCGCTGCAGCAGCAGGCGGCGTTGCCGGGCGCGGCGGCATGGGCGGGCGGTGCGCTCGCGTTCGGCTTGTGCGTGTGGC TCGCGCTCGTGTGGCGCGGCGATGCGCGCGCGCGAGCAGCCGGGTTCTGCGCATGCTGCTGCGCGGCGGCGCTCGCGGGC TTCGGCTACGCCGCGGCGCGCGCGCAGTGGCGGCTCGCCGATACGCTGCCCGCGCAGTGGGAAGGGCGCGACATCGTCGT GACGGGCGCCGTGCGCGGGCTGCCGTCGCGCGACGCGAACGGCGTGCGTTTCCTGTTCGACGTCGACGCAAACGATGCGC GCATTGCGCGTTTTCCGGCGACGCTGTCGCTTGGCTGGTACGCGTTCGGCCGCCCGGGCGCGCAGCCGCCCGAACTCGTG CCGGGCGACCGGTGGCGGCTGCGCGTGCGTCTGAAACGCCCGCACGGCAATGCGAATTTCGGCGTGCGCGACGCGGAGGC GGCGTGGCTCGCGCGCGGCATCCGGGCGCTCGGCTACGTGTCGGCGCCGCGCGATGCGCGGCGGCTCGCGGGGCGTGCAT CCGGCGTCGCGGCCGCGCTCGACCGGCTGCGCGCGCGGCTGCGCGGGCGCATCGCCGAGGCGCTCGGCGACGCCGCGCAT CGCGGGATCGTCGTCGCGCTCGCGATCGGCGCGCAGGACGATATCGCCGACGACGACCGGCGCATCCTGCGCGATACCGG CACGAGCCATCTCGTCGCGATTTCCGGGCTGCACGTCGGGATGGTCGGGGGCCTGTGCGCGTGGCTCGCGGGCGGGCTCT GGCGGCGCTCGGGCTACGTCGGACGCGACTGGCCGCTCGTCGTGCCCGCGCAGAAAGTCGCGGCGCTCGGCGCGATCGTC GGCGGCGCCGGCTATGCGGCGCTCGCGGGCTTCAACGTGCCCGTGCAGCGCGCGTGGTGGATGCTTGCCGCCGCGGGCGT CGCGTATCTGAGCGCTCGCTCGCTCGCGCCTTCGTCGGTGCTGGCGGCCGCGCTCGGCTGCGTGCTGCTCGTCGATCCGT GGGCGGTGACGTCGGCGGGGTTCTGGCTGTCGTTTTGCGCGGTCGCGGCGATCCTGGCCGTATCGTCGGGGTGGCGCGCC CCGCGCGATCTCGACGAGACGCGCGGCGCGCGCCACGCGCTCGGCGGCGTGGGTCACGAAGGCGCGCCGCCGTCGCATCG CGCGCGGTGGCGCGCCGCGTGCGGATTCGCGTGGGGGTGGGCGGCGCGCGCGTTCCGCCGGCTCGCCCGGCGCGTGCGCG ATGCCGCGCGGGCGCAGTTCGCGGTGACGATCGCGCTCGCGCCGCTCACCGTGCTGTGGTTCGCGCAGATCCCGCTCGCC GGCCCGCTCGCGAACGCGTTCGCGATTCCGTGGGTCGGCTCGCTCGTCACGCCGATCGTGCTCGCGGGCATCGTGTTGCC GGCGCCGCTCGACGCGTCCGCATACGCGCTCGCGCATACACTCGTTCAGGCGCTAATGCGGCTGCTCGACGCGACGGCCG GCGCGGGGCGCACGGTCTGGATGCTGCCGGCGCCGGACGGCTTCGCGCTCGCCGCGGCGGCGGTGGGCGTCGCGTGGGCG TTGATGCCGCGCGGCTGGCCGGTGCGCTGCGCGGCGCCGCTCGCGTGGCTGCCGCTCGTCGCGCCGGCGCCGCTTGCGCC GCCCGACGGCGCGTTCAGGCTGACGGCGCTCGACGTCGGGCAGGGCTCCGCGGTGCTGATCGAGACCGCGCGGCACACGC TGCTGTTCGACGCGGGCCCGGGGCCGGAGGCGTCGAACGCGGGCGAGCGGATCGTCGTGCCGTTCTTGCGCGCGCGAGGC GTGCGCGCGCTCGACGCGCTCGTCGTGAGCCACGCGGATTCGGATCACGCGGGCGGCGCACCCGCAGTACTCGGATCGAT CGCCGTCGCGCAGATGGCGGGCGGGCTGCCGCCGTCGAACCGCCTGTGGCGCGCCGCGCGCGCGGCCGGCGTGGCCGACG CGCTGCCGTGCGTGGCGGGGCAGCGCTGGCGCTGGGACGGCGTCGAGTTCGACGCGCTATGGCCGGCCGGCGGCCCGCGC GCGGGCGGCGCGACGAACGCGCAGTCGTGCGTGCTGCGCGTATCGGCGGGCGGGCGCGCGGCGCTCCTGACGGGCGATGT CGATGCGCGCTCCGAGCGCGCGCTCGTCGCCGGATCGCGCGGCGCGCTCGCCGCGCAGGTGCTCGTCGTGCCGCACCACG GCAGCCGCACGTCGTCGACTGAGCCTTTCCTCGATTCGGTCAAACCGCGCATTGCAATATTTCAGGTAGGCTACGCCAAC AGGTTTCACCATCCGCATCCGACCGTCTGGGCGCGCTATGCCGGGCGCGGCATCGAGTTGCCGCGCACCGACCGCGACGG CGCCGTGCGCGTCGACGTGACATCGAGCGGCGCGCTTGCCGAGCCGGTGCGGTATCGGGACGCGCACCGGCGCTACTGGA TGGGCCGTTGA
Upstream 100 bases:
>100_bases CTGCGCGGCATCGGCGTCGATGCGCTTTCCCTATCCACTTCGGCCAACGCGCTCGCCGCGCTGCCGCGGCTCGCGCTTTC GTCCGCATAATCGGTTCGTC
Downstream 100 bases:
>100_bases CGCGATGCGGAGGCTACGACAGGGAGACAGCGTCGTTTGAAGGACATCATCCATTTCTCGCATGCGAACGGCTTTCCGGC GTCCACGTATCGGACGATCT
Product: DNA internalization-related competence protein ComEC/Rec2
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 856; Mature: 856
Protein sequence:
>856_residues MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRGDARARAAGFCACCCAAALAG FGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDANGVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELV PGDRWRLRVRLKRPHGNANFGVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYVGRDWPLVVPAQKVAALGAIV GGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSVLAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRA PRDLDETRGARHALGGVGHEGAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHTLVQALMRLLDATAGAGRTVWMLPAPDGFALAAAAVGVAWA LMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVGQGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARG VRALDALVVSHADSDHAGGAPAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSSTEPFLDSVKPRIAIFQVGYAN RFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALAEPVRYRDAHRRYWMGR
Sequences:
>Translated_856_residues MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRGDARARAAGFCACCCAAALAG FGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDANGVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELV PGDRWRLRVRLKRPHGNANFGVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYVGRDWPLVVPAQKVAALGAIV GGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSVLAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRA PRDLDETRGARHALGGVGHEGAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHTLVQALMRLLDATAGAGRTVWMLPAPDGFALAAAAVGVAWA LMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVGQGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARG VRALDALVVSHADSDHAGGAPAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSSTEPFLDSVKPRIAIFQVGYAN RFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALAEPVRYRDAHRRYWMGR >Mature_856_residues MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRGDARARAAGFCACCCAAALAG FGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDANGVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELV PGDRWRLRVRLKRPHGNANFGVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYVGRDWPLVVPAQKVAALGAIV GGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSVLAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRA PRDLDETRGARHALGGVGHEGAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHTLVQALMRLLDATAGAGRTVWMLPAPDGFALAAAAVGVAWA LMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVGQGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARG VRALDALVVSHADSDHAGGAPAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSSTEPFLDSVKPRIAIFQVGYAN RFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALAEPVRYRDAHRRYWMGR
Specific function: Essential for natural transformation. Could be a transporter involved in DNA uptake [H]
COG id: COG2333
COG function: function code R; Predicted hydrolase (metallo-beta-lactamase superfamily)
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To B.subtilis ComEC, H.influenzae REC2, and E.coli YcaI [H]
Homologues:
Organism=Escherichia coli, GI87081801, Length=714, Percent_Identity=27.03081232493, Blast_Score=204, Evalue=2e-53,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 89447; Mature: 89447
Theoretical pI: Translated: 11.50; Mature: 11.50
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRG CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCC DARARAAGFCACCCAAALAGFGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDAN CCHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCC GVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELVPGDRWRLRVRLKRPHGNANF CEEEEEEECCCCCEEEECCCEEEECEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCC GVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYV CCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCHHHHCCCCC GRDWPLVVPAQKVAALGAIVGGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSV CCCCCEEECHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH LAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRAPRDLDETRGARHALGGVGHE HHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHCCCCCC GAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCC GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHTLVQALMRLLDATAGAGRTVW CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE MLPAPDGFALAAAAVGVAWALMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVG EEECCCCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHCCCCCCCCCCCCCEEEEEEECC QGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARGVRALDALVVSHADSDHAGGA CCCEEEEEECCEEEEEECCCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHCCCCCCCCCC PAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEECCCEEEEEECCCCCCC AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSST CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCC EPFLDSVKPRIAIFQVGYANRFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALA CCHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCC EPVRYRDAHRRYWMGR CCHHHHHHHHHHCCCC >Mature Secondary Structure MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRG CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCC DARARAAGFCACCCAAALAGFGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDAN CCHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCC GVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELVPGDRWRLRVRLKRPHGNANF CEEEEEEECCCCCEEEECCCEEEECEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCC GVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYV CCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCHHHHCCCCC GRDWPLVVPAQKVAALGAIVGGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSV CCCCCEEECHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH LAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRAPRDLDETRGARHALGGVGHE HHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHCCCCCC GAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCC GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHTLVQALMRLLDATAGAGRTVW CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE MLPAPDGFALAAAAVGVAWALMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVG EEECCCCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHCCCCCCCCCCCCCEEEEEEECC QGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARGVRALDALVVSHADSDHAGGA CCCEEEEEECCEEEEEECCCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHCCCCCCCCCC PAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEECCCEEEEEECCCCCCC AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSST CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCC EPFLDSVKPRIAIFQVGYANRFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALA CCHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCC EPVRYRDAHRRYWMGR CCHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7934834; 8830266 [H]