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The map label for this gene is fliY [H]

Identifier: 229918639

GI number: 229918639

Start: 2886633

End: 2887763

Strand: Direct

Name: fliY [H]

Synonym: EAT1b_2926

Alternate gene names: 229918639

Gene position: 2886633-2887763 (Clockwise)

Preceding gene: 229918638

Following gene: 229918640

Centisome position: 96.22

GC content: 48.81

Gene sequence:

>1131_bases
ATGAGTGAGATGCTGTCACAAGATGAAATTGATGCGTTATTACGCGGGACAAGCGACAATACGCCGACGCCAGAAGTCGA
TGCGAAAGAAGAACATTTAGATTCGATGGAGAGCGATGCACTCGGAGAAATTGGGAATATTTCATTCGGGAACTCGGCAA
CGGCCTTGTCAACATTACTACAACAAAAAGTTGAAATCACGACACCAGTTGTCAGTGAAGTAAGAATTGAAGCGTTACGC
GAACGCTATCCCACTCCTCATGTGGCGCTTCGGGTAGGCTACACAGAAGGGATCCAAGGGGAGAACGTCCTCGTCTTGAC
TCGCGAAGATGCGGCCATCATCTCTGACCTCATGTTAGGCGGAAGTGGAGAGAATGTCGATCCGGAGAGCCTTGATGAGA
TTCGGTTGTCGGCAGTTCAAGAAGCGATGAACCAAATGATGGGGGCGGCAGCAACGTCTTTATCGACGGTATTTTCGAAG
AAGATTGACATCTCGCCACCTCTTGTGGAAGTGTTCGATGCGACGAAGAACCAAACCATCATCGATCGCCTTGAACTTTG
GGAAACGATGGTACTCATCGAGTTCAATCTCAAGGTAGGTACGTTGATTGATTCAACAATCGTTCAGATCGCACCGATTC
AATTTGGAAAGCAATTGGTCGATGAGTTGATGAAAGCTACAGGGGAAGCCCAGGCAACACCGGAACCGGTGAAAGCGCAA
CCGCAAGCGGAAGCGCCAAAACCACAACCGCAAGCCCAACAACAGGCGCAACCAGTTGCCCCGCAACCAAGTAAACAAAA
ATCGATGCCGGAAGTGGCAGTAAGCCAAGCGGAATTCATGCCGCTCCAATCACCGGCATCGCAAGAAGCGGCACCGGCGA
ATCTTGGGTTGTTATACGATGTCCCGTTAAACGTGACAGTAGAGTTAGGAAGAACGAAAAAATCCGTTCGGGAAGTACTT
GAGTTATCACAAGGCTCCATCATCGAACTCGACAAACTAGCGGGCGAGCCGGTAGACATTTATGTCAACCAACAACGAAT
CGCTAGAGGAGAAGTCGTTGTCATTGAAGAAAACTTTGGGGTACGTGTAACAGAAATTATTCAACCGCATGAGCGGATCG
GAATCGTTTAA

Upstream 100 bases:

>100_bases
CCGTCATGGTGGGGGAAAATAAAGTATTTAAAGGGCAAGTCGGTGTGAGCGGGAAGCGAATGGCGGTTCAAGTGCTTCAC
CGTGTGAAGGAGGAAGAGCA

Downstream 100 bases:

>100_bases
GGAGGAATTTAGAATGAGTGCAAAAGTATTAGTAGTGGATGACGCAGCGTTCATGCGTATGATGATCAAGGACATTTTGA
CAAAGAATGGATATGACGTA

Product: CheC, inhibitor of MCP methylation / FliN fusion protein

Products: NA

Alternate protein names: CheY-P phosphatase FliY [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSEMLSQDEIDALLRGTSDNTPTPEVDAKEEHLDSMESDALGEIGNISFGNSATALSTLLQQKVEITTPVVSEVRIEALR
ERYPTPHVALRVGYTEGIQGENVLVLTREDAAIISDLMLGGSGENVDPESLDEIRLSAVQEAMNQMMGAAATSLSTVFSK
KIDISPPLVEVFDATKNQTIIDRLELWETMVLIEFNLKVGTLIDSTIVQIAPIQFGKQLVDELMKATGEAQATPEPVKAQ
PQAEAPKPQPQAQQQAQPVAPQPSKQKSMPEVAVSQAEFMPLQSPASQEAAPANLGLLYDVPLNVTVELGRTKKSVREVL
ELSQGSIIELDKLAGEPVDIYVNQQRIARGEVVVIEENFGVRVTEIIQPHERIGIV

Sequences:

>Translated_376_residues
MSEMLSQDEIDALLRGTSDNTPTPEVDAKEEHLDSMESDALGEIGNISFGNSATALSTLLQQKVEITTPVVSEVRIEALR
ERYPTPHVALRVGYTEGIQGENVLVLTREDAAIISDLMLGGSGENVDPESLDEIRLSAVQEAMNQMMGAAATSLSTVFSK
KIDISPPLVEVFDATKNQTIIDRLELWETMVLIEFNLKVGTLIDSTIVQIAPIQFGKQLVDELMKATGEAQATPEPVKAQ
PQAEAPKPQPQAQQQAQPVAPQPSKQKSMPEVAVSQAEFMPLQSPASQEAAPANLGLLYDVPLNVTVELGRTKKSVREVL
ELSQGSIIELDKLAGEPVDIYVNQQRIARGEVVVIEENFGVRVTEIIQPHERIGIV
>Mature_375_residues
SEMLSQDEIDALLRGTSDNTPTPEVDAKEEHLDSMESDALGEIGNISFGNSATALSTLLQQKVEITTPVVSEVRIEALRE
RYPTPHVALRVGYTEGIQGENVLVLTREDAAIISDLMLGGSGENVDPESLDEIRLSAVQEAMNQMMGAAATSLSTVFSKK
IDISPPLVEVFDATKNQTIIDRLELWETMVLIEFNLKVGTLIDSTIVQIAPIQFGKQLVDELMKATGEAQATPEPVKAQP
QAEAPKPQPQAQQQAQPVAPQPSKQKSMPEVAVSQAEFMPLQSPASQEAAPANLGLLYDVPLNVTVELGRTKKSVREVLE
LSQGSIIELDKLAGEPVDIYVNQQRIARGEVVVIEENFGVRVTEIIQPHERIGIV

Specific function: Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attr

COG id: COG1776

COG function: function code NT; Chemotaxis protein CheC, inhibitor of MCP methylation

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=The switch is localized at the base of the flagellar motor, in or near the C-ring, attached to the MS-ring (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliN/MopA/SpaO family [H]

Homologues:

Organism=Escherichia coli, GI1788256, Length=110, Percent_Identity=42.7272727272727, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007597
- InterPro:   IPR012826
- InterPro:   IPR001172
- InterPro:   IPR001543 [H]

Pfam domain/function: PF04509 CheC; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 40861; Mature: 40730

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEMLSQDEIDALLRGTSDNTPTPEVDAKEEHLDSMESDALGEIGNISFGNSATALSTLL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
QQKVEITTPVVSEVRIEALRERYPTPHVALRVGYTEGIQGENVLVLTREDAAIISDLMLG
HHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHC
GSGENVDPESLDEIRLSAVQEAMNQMMGAAATSLSTVFSKKIDISPPLVEVFDATKNQTI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHH
IDRLELWETMVLIEFNLKVGTLIDSTIVQIAPIQFGKQLVDELMKATGEAQATPEPVKAQ
HHHHHHHHEEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PQAEAPKPQPQAQQQAQPVAPQPSKQKSMPEVAVSQAEFMPLQSPASQEAAPANLGLLYD
CCCCCCCCCCCHHHHCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
VPLNVTVELGRTKKSVREVLELSQGSIIELDKLAGEPVDIYVNQQRIARGEVVVIEENFG
CCCEEEEEECCCHHHHHHHHHCCCCCEEEHHHHCCCCEEEEECHHHHCCCCEEEEECCCC
VRVTEIIQPHERIGIV
EEHHHHHCCHHHHCCC
>Mature Secondary Structure 
SEMLSQDEIDALLRGTSDNTPTPEVDAKEEHLDSMESDALGEIGNISFGNSATALSTLL
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
QQKVEITTPVVSEVRIEALRERYPTPHVALRVGYTEGIQGENVLVLTREDAAIISDLMLG
HHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHC
GSGENVDPESLDEIRLSAVQEAMNQMMGAAATSLSTVFSKKIDISPPLVEVFDATKNQTI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCHH
IDRLELWETMVLIEFNLKVGTLIDSTIVQIAPIQFGKQLVDELMKATGEAQATPEPVKAQ
HHHHHHHHEEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PQAEAPKPQPQAQQQAQPVAPQPSKQKSMPEVAVSQAEFMPLQSPASQEAAPANLGLLYD
CCCCCCCCCCCHHHHCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEE
VPLNVTVELGRTKKSVREVLELSQGSIIELDKLAGEPVDIYVNQQRIARGEVVVIEENFG
CCCEEEEEECCCHHHHHHHHHCCCCCEEEHHHHCCCCEEEEECHHHHCCCCEEEEECCCC
VRVTEIIQPHERIGIV
EEHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447979; 9384377; 1898932 [H]