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The map label for this gene is cymR [H]

Identifier: 229918428

GI number: 229918428

Start: 2685941

End: 2686348

Strand: Direct

Name: cymR [H]

Synonym: EAT1b_2715

Alternate gene names: 229918428

Gene position: 2685941-2686348 (Clockwise)

Preceding gene: 229918426

Following gene: 229918429

Centisome position: 89.53

GC content: 49.02

Gene sequence:

>408_bases
ATGAAAATATCTACAAAGGGCCGCTATGGCTTAACGATCATGATTGCATTAGCGCGTGAAACTGACAACAAGCCGCTCAG
TTTAAAGAAGATTGCCGCACGCCATGAGTTGCCGGAGCATTATTTGGAGCAATTGATCGGCCCACTCCGTAACGGTGGAC
TCGTCAAGAGCGTGCGTGGTGCGTATGGCGGCTATCAGCTCGTCAAACCGCCAGAAGAAGTGACAGCGGGTGAAATCATT
CGCTTGCTCGAGGGACCTTTAGCCATCGTTGAAGATTCTGAAGCAGATGATGCGGTGAAACGCAAGCTTTGGGATAAAAT
CAAAGAAGCCATCGATACCGTCCTTGACGAAACGACACTCGCGGACCTCGCTGAAGAAGAGTCAGACGGCTACATGTTTT
ATATTTAA

Upstream 100 bases:

>100_bases
CGAGCGGTCCACCATTCGATTGATGAAACAAATCAGGCATACGTAACCATTCCTTTCGACAAACGTTTGTTCGATTAGTA
TAACAGAAGGAGACTTGAAG

Downstream 100 bases:

>100_bases
GAACGAGGTGACCTTAGATGAACTATTTTGATCATGCTGCGACGACGCCGATGCGACCGGAAGTCCTCGAAGCGATGACA
CCGTACTTTTTAGAAACATA

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MKISTKGRYGLTIMIALARETDNKPLSLKKIAARHELPEHYLEQLIGPLRNGGLVKSVRGAYGGYQLVKPPEEVTAGEII
RLLEGPLAIVEDSEADDAVKRKLWDKIKEAIDTVLDETTLADLAEEESDGYMFYI

Sequences:

>Translated_135_residues
MKISTKGRYGLTIMIALARETDNKPLSLKKIAARHELPEHYLEQLIGPLRNGGLVKSVRGAYGGYQLVKPPEEVTAGEII
RLLEGPLAIVEDSEADDAVKRKLWDKIKEAIDTVLDETTLADLAEEESDGYMFYI
>Mature_135_residues
MKISTKGRYGLTIMIALARETDNKPLSLKKIAARHELPEHYLEQLIGPLRNGGLVKSVRGAYGGYQLVKPPEEVTAGEII
RLLEGPLAIVEDSEADDAVKRKLWDKIKEAIDTVLDETTLADLAEEESDGYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=133, Percent_Identity=30.8270676691729, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1790621, Length=136, Percent_Identity=28.6764705882353, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15027; Mature: 15027

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYGLTIMIALARETDNKPLSLKKIAARHELPEHYLEQLIGPLRNGGLVKSVRG
CCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
AYGGYQLVKPPEEVTAGEIIRLLEGPLAIVEDSEADDAVKRKLWDKIKEAIDTVLDETTL
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADLAEEESDGYMFYI
HHHHHCCCCCEEEEC
>Mature Secondary Structure
MKISTKGRYGLTIMIALARETDNKPLSLKKIAARHELPEHYLEQLIGPLRNGGLVKSVRG
CCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
AYGGYQLVKPPEEVTAGEIIRLLEGPLAIVEDSEADDAVKRKLWDKIKEAIDTVLDETTL
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ADLAEEESDGYMFYI
HHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]