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The map label for this gene is asd [H]

Identifier: 229917982

GI number: 229917982

Start: 2215453

End: 2216448

Strand: Direct

Name: asd [H]

Synonym: EAT1b_2261

Alternate gene names: 229917982

Gene position: 2215453-2216448 (Clockwise)

Preceding gene: 229917981

Following gene: 229917983

Centisome position: 73.85

GC content: 51.0

Gene sequence:

>996_bases
ATGTATAACGTAGCAGTCGTCGGTGCAACAGGTGCCGTCGGACAAAAAATGATTGACGTCTTAACGGAATATGAATTTCC
AATCAGCGAACTGAGACTCTACGCTTCAGCCCGCTCAGCAGGAAAGACGGTCGAGGTAAATGGGCAATCGGTCGTGATTC
GTGAATTGACCGATGCGATTTATGCGGACCCGATCGATATCGCACTCTTCTCTGCTGGTGGCAGCATTAGTGAGCAATAC
GCCCCACGGTTGAGCGAGCAAGGAGTCATCGTCATCGATAATTCAAGCGCATTCCGAATGCAAGAAGGAATTCCACTCAT
CGTACCGGAAGTGAACCGAGTCGAACTCAGTCCGGAAAAGACGCTCATCGCGAACCCGAACTGTTCCACGATTCAATCGG
TCGTGGCGCTCGCACCTCTAGCGGAAGTATACGGACTGACACGCGTCGCCTATACATCGTATCAAGCAGTATCGGGATCC
GGTCAAAAAGGGATTGATGACCTCGAGCGCGGTGCGCGCGGAGAAGAACCGACGAATTATCCCTATCCGATTTATGATAA
CGTGTTGCCGCACATCGATGTATTTTTAGAAAATGGCTACACAAAAGAAGAACAAAAGATGATGGATGAGACACGTAAGA
TTTTAAATGCGCCAAACCTCGGGGTGACGGCCACTTGTGTCCGGGTGCCGGTACGAAACAGTCATGCGGTATCGATCACG
GTGACGCTCGAACGGGATGCGACGGTCGCAGAAGTGAAAGCCGTCCTCGCCGATGCACCAGGAATCGTGTTGATGGACAA
TCCATCTGAACTGGCCTACCCGACACCTCTCGATGCGAACGGAACGGATGAGGTGTATGTCGGACGAATTCGCCGAGACG
ATTCACAATCGAATACGTTCCATCTTTGGTGCGTTGCAGATAACGTCCGAAAAGGAGCGGCCGCGAATGCCGTTCAAATC
GCACAATGTATGATTAGTCAAACAGCGACGAAATAA

Upstream 100 bases:

>100_bases
GACATCAGAAATCAGTATTTCCTATACGATTCAAGAACAAGATGTGGAAGCGGCAGTCGCAGCCATTGCGGCCCGGTTCA
ACTTATAAGGAGGTAGCACG

Downstream 100 bases:

>100_bases
GGAGGAGATGACATGTTCACAGGAGTGGCGACAGCATTAGCTACCCCGTTTCAAGAAAATGGGCAGTTGAATCTAGAAGC
ATGGGCAGCATTAATTGAAG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MYNVAVVGATGAVGQKMIDVLTEYEFPISELRLYASARSAGKTVEVNGQSVVIRELTDAIYADPIDIALFSAGGSISEQY
APRLSEQGVIVIDNSSAFRMQEGIPLIVPEVNRVELSPEKTLIANPNCSTIQSVVALAPLAEVYGLTRVAYTSYQAVSGS
GQKGIDDLERGARGEEPTNYPYPIYDNVLPHIDVFLENGYTKEEQKMMDETRKILNAPNLGVTATCVRVPVRNSHAVSIT
VTLERDATVAEVKAVLADAPGIVLMDNPSELAYPTPLDANGTDEVYVGRIRRDDSQSNTFHLWCVADNVRKGAAANAVQI
AQCMISQTATK

Sequences:

>Translated_331_residues
MYNVAVVGATGAVGQKMIDVLTEYEFPISELRLYASARSAGKTVEVNGQSVVIRELTDAIYADPIDIALFSAGGSISEQY
APRLSEQGVIVIDNSSAFRMQEGIPLIVPEVNRVELSPEKTLIANPNCSTIQSVVALAPLAEVYGLTRVAYTSYQAVSGS
GQKGIDDLERGARGEEPTNYPYPIYDNVLPHIDVFLENGYTKEEQKMMDETRKILNAPNLGVTATCVRVPVRNSHAVSIT
VTLERDATVAEVKAVLADAPGIVLMDNPSELAYPTPLDANGTDEVYVGRIRRDDSQSNTFHLWCVADNVRKGAAANAVQI
AQCMISQTATK
>Mature_331_residues
MYNVAVVGATGAVGQKMIDVLTEYEFPISELRLYASARSAGKTVEVNGQSVVIRELTDAIYADPIDIALFSAGGSISEQY
APRLSEQGVIVIDNSSAFRMQEGIPLIVPEVNRVELSPEKTLIANPNCSTIQSVVALAPLAEVYGLTRVAYTSYQAVSGS
GQKGIDDLERGARGEEPTNYPYPIYDNVLPHIDVFLENGYTKEEQKMMDETRKILNAPNLGVTATCVRVPVRNSHAVSIT
VTLERDATVAEVKAVLADAPGIVLMDNPSELAYPTPLDANGTDEVYVGRIRRDDSQSNTFHLWCVADNVRKGAAANAVQI
AQCMISQTATK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=336, Percent_Identity=31.8452380952381, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789841, Length=360, Percent_Identity=25.8333333333333, Blast_Score=96, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=388, Percent_Identity=29.639175257732, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 35756; Mature: 35756

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNVAVVGATGAVGQKMIDVLTEYEFPISELRLYASARSAGKTVEVNGQSVVIRELTDAI
CCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHH
YADPIDIALFSAGGSISEQYAPRLSEQGVIVIDNSSAFRMQEGIPLIVPEVNRVELSPEK
HCCCCEEEEEECCCCCCHHHCCCCCCCCEEEEECCCCEEHHCCCEEEECCCCEEEECCCC
TLIANPNCSTIQSVVALAPLAEVYGLTRVAYTSYQAVSGSGQKGIDDLERGARGEEPTNY
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCCCCCCC
PYPIYDNVLPHIDVFLENGYTKEEQKMMDETRKILNAPNLGVTATCVRVPVRNSHAVSIT
CCCCHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEEE
VTLERDATVAEVKAVLADAPGIVLMDNPSELAYPTPLDANGTDEVYVGRIRRDDSQSNTF
EEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCE
HLWCVADNVRKGAAANAVQIAQCMISQTATK
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYNVAVVGATGAVGQKMIDVLTEYEFPISELRLYASARSAGKTVEVNGQSVVIRELTDAI
CCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHH
YADPIDIALFSAGGSISEQYAPRLSEQGVIVIDNSSAFRMQEGIPLIVPEVNRVELSPEK
HCCCCEEEEEECCCCCCHHHCCCCCCCCEEEEECCCCEEHHCCCEEEECCCCEEEECCCC
TLIANPNCSTIQSVVALAPLAEVYGLTRVAYTSYQAVSGSGQKGIDDLERGARGEEPTNY
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCCCCCCC
PYPIYDNVLPHIDVFLENGYTKEEQKMMDETRKILNAPNLGVTATCVRVPVRNSHAVSIT
CCCCHHCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCEEEEE
VTLERDATVAEVKAVLADAPGIVLMDNPSELAYPTPLDANGTDEVYVGRIRRDDSQSNTF
EEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCE
HLWCVADNVRKGAAANAVQIAQCMISQTATK
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]