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The map label for this gene is yycG [H]

Identifier: 229917478

GI number: 229917478

Start: 1720860

End: 1722701

Strand: Direct

Name: yycG [H]

Synonym: EAT1b_1753

Alternate gene names: 229917478

Gene position: 1720860-1722701 (Clockwise)

Preceding gene: 229917477

Following gene: 229917479

Centisome position: 57.36

GC content: 51.3

Gene sequence:

>1842_bases
ATGAAACGGACGAACTTCTTTAAATCAATCCAGTGGAAGCTCGTCGTCATCTATGCGCTGCTCATTCTCGTTGCGATGCA
AGTCATCGGCGTGTACTTTGTGCGTTCTTTAGAACGGCAATACATCAACAACTTCTCGCAGTCACTTGTCGACCGGGCGA
ACCTACTGAGCTACAACATCAGTGAGGGGACTGCCGCGAACGAGAGTGACTCGACCACGGACCAGCAGTTGAACCAGTTA
CTGGATCAGCTGCTGTCTGAATTTACAGAGAGCACGACGCTAGCTGACGACATTCGAGAAGTCCAAATCATCGACACGAA
CAGTGTCGTCCGGGCGACCTCGAACCAAAATAATCAAAGTCTTGTCGGACAACGGACGGCGAGCACGTTCATTCAAAAGT
CATTCGCGACAGGCGGAGCGCAAGAGACGCTCGTCTATGAAGATTCAAATGACCGAATGCGCGTCGTCGCCGTTCCAATC
AAGTCGGAAGTGGACGGCACAACGACCGGGATGATCTATATCGAGGCATCGATGAAGTCCATCTACAACCAGATGGAACA
AGTGACACGCATCCTCGCAACGGGGACATTGATCGCACTCATCATCACCTCGTTCCTCGGAATCCTTTTATCTCGAACCA
TCACGCGACCGATTGCCGATATGCGGAGGCAGGCCGTCGAGATGCGGAAAGGGAACTTCTCGCGGAAAGTTAAAGTGTAT
TCGGATGACGAGGTCGGTCAACTCGCGTATGCGTTCAACGAATTGACGGATGAGTTGATGGAGGCGAACGCGACAACGGA
AGCCGAACGACGCCGCTTGACGAGTGTCCTCGAGAACATGTCGGACGGTGTGGTCGCGACTGACCGATCGCTACGGGTCA
TCTTGATGAACGACCAGGCACGCGACATGATCGGAGTCGCTGAAGAAGAGGCGATGGGGACGAACTTACAAAGTCTCCTC
GCATTCGAAGAGGAAATCGTCATTCCGGAAGACGGCACGATGCCGACAAAACTGATTGATCTCAGTACGGACGAAGAATT
GTTTCTCGTTCGTGCCTATTTCTCACCGATTCAAAAACATAGCGGACCGATTACAGGTCTCATCGTCGTCTTGCATGACG
TCACGGAACAAGAACAGGTCGAACAGGACCGCCGTGAATTCGTTGCGAACGTCAGTCATGAATTGCGGACGCCGCTCACG
ACGATGCGTAGCTATTTGGAGGTTCTCGCAGAAGGCGCGTATCAGGATGAAGAATTGGCGCCACGTTTCTTAGAAACGAC
ACAAAACGAGACGGAGCGGATGATTCGCCTCGTCAACGACTTGTTGCAGCTCTCGAAGATGGACAGTAAAGAATATAAGA
TGCAAAAAGTGAAGTTCGACTTTGTGCAGTTCTTTAACGACATTATCGACCGTCACGAGATGACGAAAGGGGATGCGATT
CAATTCCGTCGCAAACTGATGAAGCGTCGTGTCTACGTGCATGCCGATCAAGATAAGATGACCCAAGTCATCGACAACAT
CATCACGAACGCCATCAAGTTCTCACCAGAAGGCGGGACGATTACGTTCCGGACGATGCTTCGGGCGAAACGCCTTGTCA
TCGGCATCAAGGATGAAGGGGTCGGGATTCCGAAGTCGAACTTGAAGAAAATTTTCGAGCGTTTCTATCGTGTCGATAAG
GCACGGGCGCGTAACATCGGTGGTACCGGACTCGGTCTATCGATTGCCAAGGAAGTCGTTTCCGCTCACGGTGGCGACAT
CTGGGCAGAGAGTGAATTTGGAAGAGGTACAACGATTTACTTCACGATCCCATTCGATACGATTGTGGAGGTGAATGATT
GA

Upstream 100 bases:

>100_bases
TCTTCGTGAAAAAGTAGAGGACAACCCGTCGACTCCGACGTATATTATTACGCGTCGCGGCGTCGGGTATTATTTGAAGG
CAGGAGAAGAAGATTAAACG

Downstream 100 bases:

>100_bases
TGAAACGGTTTACGATTGCAAAGCCGGAACTGTGGAAGTCGTTCATTTTGCTCACGTTAATCGTCACGTCGATTGTTCAA
ACCATCATCTTATGGGACTA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MKRTNFFKSIQWKLVVIYALLILVAMQVIGVYFVRSLERQYINNFSQSLVDRANLLSYNISEGTAANESDSTTDQQLNQL
LDQLLSEFTESTTLADDIREVQIIDTNSVVRATSNQNNQSLVGQRTASTFIQKSFATGGAQETLVYEDSNDRMRVVAVPI
KSEVDGTTTGMIYIEASMKSIYNQMEQVTRILATGTLIALIITSFLGILLSRTITRPIADMRRQAVEMRKGNFSRKVKVY
SDDEVGQLAYAFNELTDELMEANATTEAERRRLTSVLENMSDGVVATDRSLRVILMNDQARDMIGVAEEEAMGTNLQSLL
AFEEEIVIPEDGTMPTKLIDLSTDEELFLVRAYFSPIQKHSGPITGLIVVLHDVTEQEQVEQDRREFVANVSHELRTPLT
TMRSYLEVLAEGAYQDEELAPRFLETTQNETERMIRLVNDLLQLSKMDSKEYKMQKVKFDFVQFFNDIIDRHEMTKGDAI
QFRRKLMKRRVYVHADQDKMTQVIDNIITNAIKFSPEGGTITFRTMLRAKRLVIGIKDEGVGIPKSNLKKIFERFYRVDK
ARARNIGGTGLGLSIAKEVVSAHGGDIWAESEFGRGTTIYFTIPFDTIVEVND

Sequences:

>Translated_613_residues
MKRTNFFKSIQWKLVVIYALLILVAMQVIGVYFVRSLERQYINNFSQSLVDRANLLSYNISEGTAANESDSTTDQQLNQL
LDQLLSEFTESTTLADDIREVQIIDTNSVVRATSNQNNQSLVGQRTASTFIQKSFATGGAQETLVYEDSNDRMRVVAVPI
KSEVDGTTTGMIYIEASMKSIYNQMEQVTRILATGTLIALIITSFLGILLSRTITRPIADMRRQAVEMRKGNFSRKVKVY
SDDEVGQLAYAFNELTDELMEANATTEAERRRLTSVLENMSDGVVATDRSLRVILMNDQARDMIGVAEEEAMGTNLQSLL
AFEEEIVIPEDGTMPTKLIDLSTDEELFLVRAYFSPIQKHSGPITGLIVVLHDVTEQEQVEQDRREFVANVSHELRTPLT
TMRSYLEVLAEGAYQDEELAPRFLETTQNETERMIRLVNDLLQLSKMDSKEYKMQKVKFDFVQFFNDIIDRHEMTKGDAI
QFRRKLMKRRVYVHADQDKMTQVIDNIITNAIKFSPEGGTITFRTMLRAKRLVIGIKDEGVGIPKSNLKKIFERFYRVDK
ARARNIGGTGLGLSIAKEVVSAHGGDIWAESEFGRGTTIYFTIPFDTIVEVND
>Mature_613_residues
MKRTNFFKSIQWKLVVIYALLILVAMQVIGVYFVRSLERQYINNFSQSLVDRANLLSYNISEGTAANESDSTTDQQLNQL
LDQLLSEFTESTTLADDIREVQIIDTNSVVRATSNQNNQSLVGQRTASTFIQKSFATGGAQETLVYEDSNDRMRVVAVPI
KSEVDGTTTGMIYIEASMKSIYNQMEQVTRILATGTLIALIITSFLGILLSRTITRPIADMRRQAVEMRKGNFSRKVKVY
SDDEVGQLAYAFNELTDELMEANATTEAERRRLTSVLENMSDGVVATDRSLRVILMNDQARDMIGVAEEEAMGTNLQSLL
AFEEEIVIPEDGTMPTKLIDLSTDEELFLVRAYFSPIQKHSGPITGLIVVLHDVTEQEQVEQDRREFVANVSHELRTPLT
TMRSYLEVLAEGAYQDEELAPRFLETTQNETERMIRLVNDLLQLSKMDSKEYKMQKVKFDFVQFFNDIIDRHEMTKGDAI
QFRRKLMKRRVYVHADQDKMTQVIDNIITNAIKFSPEGGTITFRTMLRAKRLVIGIKDEGVGIPKSNLKKIFERFYRVDK
ARARNIGGTGLGLSIAKEVVSAHGGDIWAESEFGRGTTIYFTIPFDTIVEVND

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=349, Percent_Identity=33.2378223495702, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=32.618025751073, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=31.5126050420168, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=26.3852242744063, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=30.4721030042918, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=28.2051282051282, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI48994928, Length=272, Percent_Identity=27.5735294117647, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=28.6307053941909, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=28.0193236714976, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=26.7857142857143, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=24.5762711864407, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87081816, Length=239, Percent_Identity=26.7782426778243, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790436, Length=226, Percent_Identity=29.646017699115, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=26.5217391304348, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790551, Length=246, Percent_Identity=27.2357723577236, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789403, Length=214, Percent_Identity=28.9719626168224, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790300, Length=360, Percent_Identity=24.7222222222222, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=214, Percent_Identity=27.1028037383178, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788279, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69474; Mature: 69474

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTNFFKSIQWKLVVIYALLILVAMQVIGVYFVRSLERQYINNFSQSLVDRANLLSYNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
SEGTAANESDSTTDQQLNQLLDQLLSEFTESTTLADDIREVQIIDTNSVVRATSNQNNQS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEEEECCCEEEECCCCCCHH
LVGQRTASTFIQKSFATGGAQETLVYEDSNDRMRVVAVPIKSEVDGTTTGMIYIEASMKS
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEEHHHHH
IYNQMEQVTRILATGTLIALIITSFLGILLSRTITRPIADMRRQAVEMRKGNFSRKVKVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
SDDEVGQLAYAFNELTDELMEANATTEAERRRLTSVLENMSDGVVATDRSLRVILMNDQA
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEEECCCC
RDMIGVAEEEAMGTNLQSLLAFEEEIVIPEDGTMPTKLIDLSTDEELFLVRAYFSPIQKH
HHHHCCCHHHHHCCCHHHHHHHHHCEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHC
SGPITGLIVVLHDVTEQEQVEQDRREFVANVSHELRTPLTTMRSYLEVLAEGAYQDEELA
CCCHHEEHEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHH
PRFLETTQNETERMIRLVNDLLQLSKMDSKEYKMQKVKFDFVQFFNDIIDRHEMTKGDAI
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QFRRKLMKRRVYVHADQDKMTQVIDNIITNAIKFSPEGGTITFRTMLRAKRLVIGIKDEG
HHHHHHHHHHEEEECCHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHEEEECCCC
VGIPKSNLKKIFERFYRVDKARARNIGGTGLGLSIAKEVVSAHGGDIWAESEFGRGTTIY
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEE
FTIPFDTIVEVND
EEECCCEEEEECC
>Mature Secondary Structure
MKRTNFFKSIQWKLVVIYALLILVAMQVIGVYFVRSLERQYINNFSQSLVDRANLLSYNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
SEGTAANESDSTTDQQLNQLLDQLLSEFTESTTLADDIREVQIIDTNSVVRATSNQNNQS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHEEEEEECCCEEEECCCCCCHH
LVGQRTASTFIQKSFATGGAQETLVYEDSNDRMRVVAVPIKSEVDGTTTGMIYIEASMKS
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEEHHHHH
IYNQMEQVTRILATGTLIALIITSFLGILLSRTITRPIADMRRQAVEMRKGNFSRKVKVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
SDDEVGQLAYAFNELTDELMEANATTEAERRRLTSVLENMSDGVVATDRSLRVILMNDQA
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEEECCCC
RDMIGVAEEEAMGTNLQSLLAFEEEIVIPEDGTMPTKLIDLSTDEELFLVRAYFSPIQKH
HHHHCCCHHHHHCCCHHHHHHHHHCEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHC
SGPITGLIVVLHDVTEQEQVEQDRREFVANVSHELRTPLTTMRSYLEVLAEGAYQDEELA
CCCHHEEHEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHH
PRFLETTQNETERMIRLVNDLLQLSKMDSKEYKMQKVKFDFVQFFNDIIDRHEMTKGDAI
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QFRRKLMKRRVYVHADQDKMTQVIDNIITNAIKFSPEGGTITFRTMLRAKRLVIGIKDEG
HHHHHHHHHHEEEECCHHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHEEEECCCC
VGIPKSNLKKIFERFYRVDKARARNIGGTGLGLSIAKEVVSAHGGDIWAESEFGRGTTIY
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEE
FTIPFDTIVEVND
EEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]