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The map label for this gene is yycF [H]

Identifier: 229917477

GI number: 229917477

Start: 1720146

End: 1720856

Strand: Direct

Name: yycF [H]

Synonym: EAT1b_1752

Alternate gene names: 229917477

Gene position: 1720146-1720856 (Clockwise)

Preceding gene: 229917476

Following gene: 229917478

Centisome position: 57.34

GC content: 49.37

Gene sequence:

>711_bases
ATGGATCGTACGATTTTAGTGGTAGATGACGAACAACCAATCGCAGATATATTGAAGTTTAAACTTGAAAAAGAAGGTTA
CCAGGTGCATGTCGCCTATGACGGCGAAGAAGCGCTCGTCAAAGTAGAAGAGATTCAACCGGATCTCATCTTGCTCGACA
TCATGCTTCCGCTCAAAGACGGCATGGAAGTATGCCGTGAGGTACGGAAGAAGTATGACATGCCGATCATCATGTTGACG
GCGAAAGATTCCGAGATTGACAAAGTACTCGGACTAGAGCTCGGTGCAGACGATTACGTCACAAAGCCGTTCAGCTCACG
TGAATTGTTAGCCCGTGTCAAAGCGAACATGCGACGTCATGCGACAGCACCGGCGCCAGAAGCAAAAGGAGCCAACGCGA
ACGATATCGTGATCGGCGACTTGACGATTCATCCGGATTCGTACATGGTGACGAAACGGGATGAGAAAATCGAATTGACG
CATCGCGAGTTCGAATTGATTCATTACCTCGCCCAAAACATCGGGCAAGTGATGACGCGGGAGCACTTGCTCCAAACGGT
GTGGGGCTATGATTACTTCGGTGATGTGCGTACTGTGGACGTCACGGTGCGTCGTCTTCGTGAAAAAGTAGAGGACAACC
CGTCGACTCCGACGTATATTATTACGCGTCGCGGCGTCGGGTATTATTTGAAGGCAGGAGAAGAAGATTAA

Upstream 100 bases:

>100_bases
CTTTTTCTATTTCCACGGAAATGGACCACGCTTTCTAAGCGGTTTAAAAAGAGTTACAATGTAGGCATGTACGTTTAATG
ATAAGAGGAGGACTCACTGA

Downstream 100 bases:

>100_bases
ACGATGAAACGGACGAACTTCTTTAAATCAATCCAGTGGAAGCTCGTCGTCATCTATGCGCTGCTCATTCTCGTTGCGAT
GCAAGTCATCGGCGTGTACT

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MDRTILVVDDEQPIADILKFKLEKEGYQVHVAYDGEEALVKVEEIQPDLILLDIMLPLKDGMEVCREVRKKYDMPIIMLT
AKDSEIDKVLGLELGADDYVTKPFSSRELLARVKANMRRHATAPAPEAKGANANDIVIGDLTIHPDSYMVTKRDEKIELT
HREFELIHYLAQNIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSTPTYIITRRGVGYYLKAGEED

Sequences:

>Translated_236_residues
MDRTILVVDDEQPIADILKFKLEKEGYQVHVAYDGEEALVKVEEIQPDLILLDIMLPLKDGMEVCREVRKKYDMPIIMLT
AKDSEIDKVLGLELGADDYVTKPFSSRELLARVKANMRRHATAPAPEAKGANANDIVIGDLTIHPDSYMVTKRDEKIELT
HREFELIHYLAQNIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSTPTYIITRRGVGYYLKAGEED
>Mature_236_residues
MDRTILVVDDEQPIADILKFKLEKEGYQVHVAYDGEEALVKVEEIQPDLILLDIMLPLKDGMEVCREVRKKYDMPIIMLT
AKDSEIDKVLGLELGADDYVTKPFSSRELLARVKANMRRHATAPAPEAKGANANDIVIGDLTIHPDSYMVTKRDEKIELT
HREFELIHYLAQNIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSTPTYIITRRGVGYYLKAGEED

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=41.5584415584416, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=40.7079646017699, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=38.3259911894273, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.5638766519824, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=39.3013100436681, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=37.719298245614, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790860, Length=237, Percent_Identity=37.1308016877637, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=36.3247863247863, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=37.6068376068376, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=38.1578947368421, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=33.9055793991416, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=33.4763948497854, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.5991189427313, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=33.6244541484716, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=37.7358490566038, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=156, Percent_Identity=28.2051282051282, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27063; Mature: 27063

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRTILVVDDEQPIADILKFKLEKEGYQVHVAYDGEEALVKVEEIQPDLILLDIMLPLKD
CCCEEEEEECCCCHHHHHHHHCCCCCEEEEEEECCHHHEEEEECCCCCEEEEEEHHCHHH
GMEVCREVRKKYDMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSSRELLARVKANMRRH
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHC
ATAPAPEAKGANANDIVIGDLTIHPDSYMVTKRDEKIELTHREFELIHYLAQNIGQVMTR
CCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHH
EHLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSTPTYIITRRGVGYYLKAGEED
HHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCCC
>Mature Secondary Structure
MDRTILVVDDEQPIADILKFKLEKEGYQVHVAYDGEEALVKVEEIQPDLILLDIMLPLKD
CCCEEEEEECCCCHHHHHHHHCCCCCEEEEEEECCHHHEEEEECCCCCEEEEEEHHCHHH
GMEVCREVRKKYDMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSSRELLARVKANMRRH
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHC
ATAPAPEAKGANANDIVIGDLTIHPDSYMVTKRDEKIELTHREFELIHYLAQNIGQVMTR
CCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHH
EHLLQTVWGYDYFGDVRTVDVTVRRLREKVEDNPSTPTYIITRRGVGYYLKAGEED
HHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]