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The map label for this gene is rbsK [H]

Identifier: 229917244

GI number: 229917244

Start: 1487741

End: 1488625

Strand: Reverse

Name: rbsK [H]

Synonym: EAT1b_1519

Alternate gene names: 229917244

Gene position: 1488625-1487741 (Counterclockwise)

Preceding gene: 229917245

Following gene: 229917243

Centisome position: 49.62

GC content: 51.86

Gene sequence:

>885_bases
ATGAAACGCATTGTTGTCATTGGCAGTATATCGATGGACCTTGTCGTCACGTCCGACAAACGTCCACAAGCTGGAGAAAC
GGTTATCGGTGAATCGTTCCGTACCGTTCCAGGGGGGAAAGGTGCGAACCAGGCAGTCGCTGCTTCCAAGTTAGGCGGCA
CTGTACAGATGGTCGGTTGCGTGGGAAGTGATCCGTTCGGACAACAGGTGGTTGAAAACTTCAAACGACACGATGTCGAT
GTCACACATGTTCAAATCATACGGGATGAAGTGACGGGTACGGCCCATATCGTATTGGCTGAGGAAGATAATTCGATCGT
CGTCGTCCAATCGGCGAACAAACGAGTCGTTTTCACGAATGAGGAGCTCGAACACCTTCTTGACGAGCAGGCATTCGTGC
TCCTCCAACTCGAAATTCCAATCGAGACGGTAAAGCAAGTGACCTCTTACTGTAAAGCGAAAGGAATCCCAGTGCTGCTC
AATCCGGCACCTTCTCAGCCGCTTCCACCAGAAGTGATTGAAAACGTCACATACTTGACGCCGAACGAACATGAGTGCCG
TGACTTATTCAACGGAATATCCGTAGATGATGTTCTCAAACGCTATCCGAACAAGTTACTCGTCACGGAAGGCGTCCATG
GTGTTCGATTCCATGACGGACGAGACGTGCGGCATGTGCCAGCCATCCGAGCAAACGTCGTCGACACAACAGGAGCAGGT
GACACGTTCAACGGTGCACTTGCTGTCTCCCTCATCGAACAAGACGATTTGGAGACGGCCGTACGGTTTGCCGTAGTCGC
ATCCGGCATGAGTGTCGAAGGCTTCGGTGCACAAGGTGGTATGCCGACACGACAAGATGTACAACAACGATTGGAGCGCG
TGTGA

Upstream 100 bases:

>100_bases
GCTCGATTTGATTGAGAAGAAAGACACACGACCGAGAGAAATGCTGTTACCGGTCACGTTACTTGAACGACACACGACAA
AGCGGAAGGAGAGATAAAGA

Downstream 100 bases:

>100_bases
TGAAAAAACAAGGAATTTTGAATAGTCATTTAGCAAAAATCTTTGCCGACCTCGGGCATACGGATCGCGTCGTCATCGCC
GATTGTGGGCTACCGATTCC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKRIVVIGSISMDLVVTSDKRPQAGETVIGESFRTVPGGKGANQAVAASKLGGTVQMVGCVGSDPFGQQVVENFKRHDVD
VTHVQIIRDEVTGTAHIVLAEEDNSIVVVQSANKRVVFTNEELEHLLDEQAFVLLQLEIPIETVKQVTSYCKAKGIPVLL
NPAPSQPLPPEVIENVTYLTPNEHECRDLFNGISVDDVLKRYPNKLLVTEGVHGVRFHDGRDVRHVPAIRANVVDTTGAG
DTFNGALAVSLIEQDDLETAVRFAVVASGMSVEGFGAQGGMPTRQDVQQRLERV

Sequences:

>Translated_294_residues
MKRIVVIGSISMDLVVTSDKRPQAGETVIGESFRTVPGGKGANQAVAASKLGGTVQMVGCVGSDPFGQQVVENFKRHDVD
VTHVQIIRDEVTGTAHIVLAEEDNSIVVVQSANKRVVFTNEELEHLLDEQAFVLLQLEIPIETVKQVTSYCKAKGIPVLL
NPAPSQPLPPEVIENVTYLTPNEHECRDLFNGISVDDVLKRYPNKLLVTEGVHGVRFHDGRDVRHVPAIRANVVDTTGAG
DTFNGALAVSLIEQDDLETAVRFAVVASGMSVEGFGAQGGMPTRQDVQQRLERV
>Mature_294_residues
MKRIVVIGSISMDLVVTSDKRPQAGETVIGESFRTVPGGKGANQAVAASKLGGTVQMVGCVGSDPFGQQVVENFKRHDVD
VTHVQIIRDEVTGTAHIVLAEEDNSIVVVQSANKRVVFTNEELEHLLDEQAFVLLQLEIPIETVKQVTSYCKAKGIPVLL
NPAPSQPLPPEVIENVTYLTPNEHECRDLFNGISVDDVLKRYPNKLLVTEGVHGVRFHDGRDVRHVPAIRANVVDTTGAG
DTFNGALAVSLIEQDDLETAVRFAVVASGMSVEGFGAQGGMPTRQDVQQRLERV

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=299, Percent_Identity=32.4414715719064, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1790193, Length=303, Percent_Identity=35.6435643564356, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI87082343, Length=286, Percent_Identity=24.1258741258741, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081971, Length=281, Percent_Identity=24.1992882562278, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532905, Length=305, Percent_Identity=33.1147540983607, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=33.8368580060423, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=32, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24583886, Length=308, Percent_Identity=26.6233766233766, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31836; Mature: 31836

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVVIGSISMDLVVTSDKRPQAGETVIGESFRTVPGGKGANQAVAASKLGGTVQMVGC
CCEEEEEECCEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEE
VGSDPFGQQVVENFKRHDVDVTHVQIIRDEVTGTAHIVLAEEDNSIVVVQSANKRVVFTN
CCCCCHHHHHHHHHHHCCCCCHHEEEEECCCCCEEEEEEEECCCCEEEEECCCCEEEEEC
EELEHLLDEQAFVLLQLEIPIETVKQVTSYCKAKGIPVLLNPAPSQPLPPEVIENVTYLT
HHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHCCCEEEC
PNEHECRDLFNGISVDDVLKRYPNKLLVTEGVHGVRFHDGRDVRHVPAIRANVVDTTGAG
CCHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCCCC
DTFNGALAVSLIEQDDLETAVRFAVVASGMSVEGFGAQGGMPTRQDVQQRLERV
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKRIVVIGSISMDLVVTSDKRPQAGETVIGESFRTVPGGKGANQAVAASKLGGTVQMVGC
CCEEEEEECCEEEEEEECCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEE
VGSDPFGQQVVENFKRHDVDVTHVQIIRDEVTGTAHIVLAEEDNSIVVVQSANKRVVFTN
CCCCCHHHHHHHHHHHCCCCCHHEEEEECCCCCEEEEEEEECCCCEEEEECCCCEEEEEC
EELEHLLDEQAFVLLQLEIPIETVKQVTSYCKAKGIPVLLNPAPSQPLPPEVIENVTYLT
HHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHCCCEEEC
PNEHECRDLFNGISVDDVLKRYPNKLLVTEGVHGVRFHDGRDVRHVPAIRANVVDTTGAG
CCHHHHHHHHCCCCHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCCCC
DTFNGALAVSLIEQDDLETAVRFAVVASGMSVEGFGAQGGMPTRQDVQQRLERV
CCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]