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The map label for this gene is hisC [H]

Identifier: 229915826

GI number: 229915826

Start: 70580

End: 71593

Strand: Reverse

Name: hisC [H]

Synonym: EAT1b_0093

Alternate gene names: 229915826

Gene position: 71593-70580 (Counterclockwise)

Preceding gene: 229915827

Following gene: 229915824

Centisome position: 2.39

GC content: 48.13

Gene sequence:

>1014_bases
ATGAGACAAGTCGAGCTTCCGATTTATCCCGTCGTTTATCCGACGGGACATCGGTTAAACCAAAATGAAAGTCAGTTCCC
GTTACCTGACCGCATCAAGAATCAGCTTGATTCGTTGACGTATCATGACTTACACGAGTATCCAGTCGAACCAATCAATG
AGTTGTTCGAACGCTACGCTGCTTACGCCGGCGTCACACCTGAGCAATTACTCGTCGGTTGTGGGAGTGATGAGATGATC
CATGTCGTGACGCAAGCGTTGCTCGCACCACATGATATCGTCTTATCTCCGGCACCTGACTTTTCAATGTATCCCATCTT
CACGACCATCGCACACGGTCATCATGTTCAAGCCGTTGATTTATCGTATGAAGGAATGGTAAAGGCGATTGAGACGCATC
ATCCAAAGCTTCTTCTTCTTTCGAACCCAAACAATCCAACCGGAAAGCTGTGGACCATAGAAGAGTTGACGCATCTCGCC
TCACTCGTGCCATATATCGTGGTGGATGAGGCCTATATGGACTTCACACCAGATGCGAGCATGATCCCGTTCATTGCCAC
CCTTCCGAATCTCATCGTCCTTCGCACGATGTCAAAAGCGTTCGGATTGGCAAACGTACGAATCGGATTCATGGTGACAA
ACTGCGAACTCGCACACTATTTCCGTCAATTCATCCCGCCATTTAATATTAGCGGAGTGAGCGCGAAAATCTGCAATATC
TTCTTAAAAGATGCGACTTATCTTCAAGAAACAATCGAATGGCATGACGAGATGCGGCAAAAGTGGGCGCAAGCCTTTAA
AGCCATCGGTCATGTCATCCCTGCCACGACGAACTTTTTGTATGTCGAGCTCGAGCAACCTGAAGCAGTGTGGGCCCATT
TGACTGACTTGAACGTACACACGTCGAAACAACCGACGGGGATTCGGGTGACGATTGGGGACGAGGCGGCGCTTCATCTT
GCACATACAGCTATTCAACAGTACATGGAAACAAGTCATGTAAAAAACTCCTGA

Upstream 100 bases:

>100_bases
ATGAGTTACGCGACCAGTTCAACGAAGAGCTGAACAAGATGATGGAGTCTGGCGAAATCGATGAATTGGTGAAAAAATGG
TTCTCGATGGAGCCTACTGA

Downstream 100 bases:

>100_bases
ACCTCGTGTTCAGGAGTTTTTGTCAGTCGATCGTCTTGATCACACGCGCCGGATTTCCTCCGACGACTGTTCGAGGCGGT
ACATCTTTTGTGACGACGGC

Product: aminotransferase class I and II

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRQVELPIYPVVYPTGHRLNQNESQFPLPDRIKNQLDSLTYHDLHEYPVEPINELFERYAAYAGVTPEQLLVGCGSDEMI
HVVTQALLAPHDIVLSPAPDFSMYPIFTTIAHGHHVQAVDLSYEGMVKAIETHHPKLLLLSNPNNPTGKLWTIEELTHLA
SLVPYIVVDEAYMDFTPDASMIPFIATLPNLIVLRTMSKAFGLANVRIGFMVTNCELAHYFRQFIPPFNISGVSAKICNI
FLKDATYLQETIEWHDEMRQKWAQAFKAIGHVIPATTNFLYVELEQPEAVWAHLTDLNVHTSKQPTGIRVTIGDEAALHL
AHTAIQQYMETSHVKNS

Sequences:

>Translated_337_residues
MRQVELPIYPVVYPTGHRLNQNESQFPLPDRIKNQLDSLTYHDLHEYPVEPINELFERYAAYAGVTPEQLLVGCGSDEMI
HVVTQALLAPHDIVLSPAPDFSMYPIFTTIAHGHHVQAVDLSYEGMVKAIETHHPKLLLLSNPNNPTGKLWTIEELTHLA
SLVPYIVVDEAYMDFTPDASMIPFIATLPNLIVLRTMSKAFGLANVRIGFMVTNCELAHYFRQFIPPFNISGVSAKICNI
FLKDATYLQETIEWHDEMRQKWAQAFKAIGHVIPATTNFLYVELEQPEAVWAHLTDLNVHTSKQPTGIRVTIGDEAALHL
AHTAIQQYMETSHVKNS
>Mature_337_residues
MRQVELPIYPVVYPTGHRLNQNESQFPLPDRIKNQLDSLTYHDLHEYPVEPINELFERYAAYAGVTPEQLLVGCGSDEMI
HVVTQALLAPHDIVLSPAPDFSMYPIFTTIAHGHHVQAVDLSYEGMVKAIETHHPKLLLLSNPNNPTGKLWTIEELTHLA
SLVPYIVVDEAYMDFTPDASMIPFIATLPNLIVLRTMSKAFGLANVRIGFMVTNCELAHYFRQFIPPFNISGVSAKICNI
FLKDATYLQETIEWHDEMRQKWAQAFKAIGHVIPATTNFLYVELEQPEAVWAHLTDLNVHTSKQPTGIRVTIGDEAALHL
AHTAIQQYMETSHVKNS

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=298, Percent_Identity=31.8791946308725, Blast_Score=127, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322075, Length=288, Percent_Identity=27.4305555555556, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38073; Mature: 38073

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQVELPIYPVVYPTGHRLNQNESQFPLPDRIKNQLDSLTYHDLHEYPVEPINELFERYA
CCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHH
AYAGVTPEQLLVGCGSDEMIHVVTQALLAPHDIVLSPAPDFSMYPIFTTIAHGHHVQAVD
HHCCCCHHHHEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHCCCCEEEEEE
LSYEGMVKAIETHHPKLLLLSNPNNPTGKLWTIEELTHLASLVPYIVVDEAYMDFTPDAS
CCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHEEECHHHCCCCCCC
MIPFIATLPNLIVLRTMSKAFGLANVRIGFMVTNCELAHYFRQFIPPFNISGVSAKICNI
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHH
FLKDATYLQETIEWHDEMRQKWAQAFKAIGHVIPATTNFLYVELEQPEAVWAHLTDLNVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECEEE
TSKQPTGIRVTIGDEAALHLAHTAIQQYMETSHVKNS
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRQVELPIYPVVYPTGHRLNQNESQFPLPDRIKNQLDSLTYHDLHEYPVEPINELFERYA
CCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHH
AYAGVTPEQLLVGCGSDEMIHVVTQALLAPHDIVLSPAPDFSMYPIFTTIAHGHHVQAVD
HHCCCCHHHHEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHCCCCEEEEEE
LSYEGMVKAIETHHPKLLLLSNPNNPTGKLWTIEELTHLASLVPYIVVDEAYMDFTPDAS
CCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHEEECHHHCCCCCCC
MIPFIATLPNLIVLRTMSKAFGLANVRIGFMVTNCELAHYFRQFIPPFNISGVSAKICNI
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHH
FLKDATYLQETIEWHDEMRQKWAQAFKAIGHVIPATTNFLYVELEQPEAVWAHLTDLNVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECEEE
TSKQPTGIRVTIGDEAALHLAHTAIQQYMETSHVKNS
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA