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The map label for this gene is dcm [C]

Identifier: 227828127

GI number: 227828127

Start: 1712097

End: 1713074

Strand: Direct

Name: dcm [C]

Synonym: M1425_1865

Alternate gene names: 227828127

Gene position: 1712097-1713074 (Clockwise)

Preceding gene: 227828126

Following gene: 227828128

Centisome position: 65.63

GC content: 33.44

Gene sequence:

>978_bases
TTGGGGCAAATAAAAGTCATTGATCTATTTTCTGGAGCAGGAGGATTTTCATTAGGTTTCAAAAAATTAGGAATAGAGCC
TAAATTAGCAATAGATATAAATCACGCTGCAGCTAGAACATATTCATTAAATTTTCCAAATACAATAGTAATTGAAGACG
ATATAAGACAAATAAGTGGAAAAGAGATTTTAAAAAATGTAGGGGATGAAATAGACGTAATAATTGGAGGCCCTCCATGT
GAGGGATATACTGCAGCTAATCCCTTACGTATGCAAGATCCTTTAGATAGATTATATTTAGATCAAAGAGGGAGTTTAAC
ACTGGAATTCATAAGGATTGTGGATGAACTAAAACCGAAAATCTTTGTAATGGAAAATGTTCCAGCGATTATTGAAACTC
AATCACTAAGAGATGCTCTAATTAATGAATTTAAAAGAGCTGGATACAATAATATATTCTTCAATATATTACATGCTGAA
GATTATGGTAACCCATCTAAACGAAATAGGGTATTCATCTCAAACGTTAAAATATTGCCTATTAAAATTCAAAAAAGAGT
CACAGTTTATGATGCGATTCATGATTTAGATAGCAAACTAGACGTTCCTAATAACGAGGTAAGCGAGCCTAACGAGAAAA
AACTTCTGAAAATTTCTAAAATTGGGTACGGAGAGTATTTAACAATGTACAAGGCGAGTAAGGGAAAAAGTATGCCACTA
TATATTAGACTTTCTCCATTCGATCTAGCACCTACAATTTTGGGTAATTCTAGATTTATACACCCATTCCATGATAGATT
CTTAACTGTGAGAGAGCAGGCCAGACTAATGAGTTATCCTGATGATCATGTATTTTTAGGAAGCAAAGATGAACAGTATA
ATCAAGTAGGCGAATCTGTTCCAGTAGCCTTATCTACCGCTATAGCTAAAGAGATTCTGGGTATACTAAATGAAAGAGTT
ATATTTCGGCCTACATAA

Upstream 100 bases:

>100_bases
TGTGGATCTCAACTAACCTACTATGATACGGAAAAGATTAAGTCATTCTTGGAGCAAAAAATAAGACAAATAGAGGAAGA
GATAGATAAGGAGACAAAAC

Downstream 100 bases:

>100_bases
CCTAACTAGTAATCAAAGACTCTTGGACTTTTCTAAATTAGCCTTTAATATAAAGTACGTAAAGTATTTAGTTCTCACTA
AGTTAGGTGGGACAGCTGCG

Product: DNA-cytosine methyltransferase

Products: NA

Alternate protein names: Cytosine-specific methyltransferase MJ1200; M.MjaVIIP [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MGQIKVIDLFSGAGGFSLGFKKLGIEPKLAIDINHAAARTYSLNFPNTIVIEDDIRQISGKEILKNVGDEIDVIIGGPPC
EGYTAANPLRMQDPLDRLYLDQRGSLTLEFIRIVDELKPKIFVMENVPAIIETQSLRDALINEFKRAGYNNIFFNILHAE
DYGNPSKRNRVFISNVKILPIKIQKRVTVYDAIHDLDSKLDVPNNEVSEPNEKKLLKISKIGYGEYLTMYKASKGKSMPL
YIRLSPFDLAPTILGNSRFIHPFHDRFLTVREQARLMSYPDDHVFLGSKDEQYNQVGESVPVALSTAIAKEILGILNERV
IFRPT

Sequences:

>Translated_325_residues
MGQIKVIDLFSGAGGFSLGFKKLGIEPKLAIDINHAAARTYSLNFPNTIVIEDDIRQISGKEILKNVGDEIDVIIGGPPC
EGYTAANPLRMQDPLDRLYLDQRGSLTLEFIRIVDELKPKIFVMENVPAIIETQSLRDALINEFKRAGYNNIFFNILHAE
DYGNPSKRNRVFISNVKILPIKIQKRVTVYDAIHDLDSKLDVPNNEVSEPNEKKLLKISKIGYGEYLTMYKASKGKSMPL
YIRLSPFDLAPTILGNSRFIHPFHDRFLTVREQARLMSYPDDHVFLGSKDEQYNQVGESVPVALSTAIAKEILGILNERV
IFRPT
>Mature_324_residues
GQIKVIDLFSGAGGFSLGFKKLGIEPKLAIDINHAAARTYSLNFPNTIVIEDDIRQISGKEILKNVGDEIDVIIGGPPCE
GYTAANPLRMQDPLDRLYLDQRGSLTLEFIRIVDELKPKIFVMENVPAIIETQSLRDALINEFKRAGYNNIFFNILHAED
YGNPSKRNRVFISNVKILPIKIQKRVTVYDAIHDLDSKLDVPNNEVSEPNEKKLLKISKIGYGEYLTMYKASKGKSMPLY
IRLSPFDLAPTILGNSRFIHPFHDRFLTVREQARLMSYPDDHVFLGSKDEQYNQVGESVPVALSTAIAKEILGILNERVI
FRPT

Specific function: This Methylase Recognizes The Double-Stranded Sequence Ccwgg, Causes Specific Methylation On C-2 On Both Strands. [C]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI195927037, Length=187, Percent_Identity=28.3422459893048, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4503351, Length=187, Percent_Identity=28.3422459893048, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4758184, Length=225, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788271, Length=226, Percent_Identity=26.9911504424779, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 36679; Mature: 36548

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQIKVIDLFSGAGGFSLGFKKLGIEPKLAIDINHAAARTYSLNFPNTIVIEDDIRQISG
CCCEEEEEEECCCCCCCCCHHHCCCCCEEEEEECCCEEEEEECCCCCEEEECHHHHHCCH
KEILKNVGDEIDVIIGGPPCEGYTAANPLRMQDPLDRLYLDQRGSLTLEFIRIVDELKPK
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCC
IFVMENVPAIIETQSLRDALINEFKRAGYNNIFFNILHAEDYGNPSKRNRVFISNVKILP
EEEEECCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEEEECEEEEE
IKIQKRVTVYDAIHDLDSKLDVPNNEVSEPNEKKLLKISKIGYGEYLTMYKASKGKSMPL
EEEECEEEHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEEECCCCCEEEEEECCCCCCCEE
YIRLSPFDLAPTILGNSRFIHPFHDRFLTVREQARLMSYPDDHVFLGSKDEQYNQVGESV
EEEECCCCCCHHEECCCCEECHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCC
PVALSTAIAKEILGILNERVIFRPT
CHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
GQIKVIDLFSGAGGFSLGFKKLGIEPKLAIDINHAAARTYSLNFPNTIVIEDDIRQISG
CCEEEEEEECCCCCCCCCHHHCCCCCEEEEEECCCEEEEEECCCCCEEEECHHHHHCCH
KEILKNVGDEIDVIIGGPPCEGYTAANPLRMQDPLDRLYLDQRGSLTLEFIRIVDELKPK
HHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCC
IFVMENVPAIIETQSLRDALINEFKRAGYNNIFFNILHAEDYGNPSKRNRVFISNVKILP
EEEEECCCCEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEEEEECEEEEE
IKIQKRVTVYDAIHDLDSKLDVPNNEVSEPNEKKLLKISKIGYGEYLTMYKASKGKSMPL
EEEECEEEHHHHHHHHHHHCCCCCCCCCCCCHHHEEEEEECCCCCEEEEEECCCCCCCEE
YIRLSPFDLAPTILGNSRFIHPFHDRFLTVREQARLMSYPDDHVFLGSKDEQYNQVGESV
EEEECCCCCCHHEECCCCEECHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCC
PVALSTAIAKEILGILNERVIFRPT
CHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]