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The map label for this gene is hflX [C]

Identifier: 227828124

GI number: 227828124

Start: 1709987

End: 1711057

Strand: Direct

Name: hflX [C]

Synonym: M1425_1862

Alternate gene names: 227828124

Gene position: 1709987-1711057 (Clockwise)

Preceding gene: 227828123

Following gene: 227828125

Centisome position: 65.55

GC content: 32.77

Gene sequence:

>1071_bases
GTGAAAAGTGCAGTTCTTTTTGTATCTGAAGAATTTAAGGAAGAGGCAATCGCGTTAGTTGAGGGGGCTAACTACAAGAT
AGTTAGGATTTACAAATTACCAAAATCGCCTAATGTGAAATTTTATATACAATATGATAAGCTGCAACAAATCAAAAACG
ACGAGGAGATTTCCACTTTAATCGTATTCGAACAACTTAAGCCCAGACACTTTATAAATCTGAGAAAAGAACTAAAAGGA
AAAGAGATCCTAGACAAAATACTCCTTCTCTTAGAAATATTTGCATTGCATGCAGGATCAAAAGAAGCAAAAATGCAAAT
AGAACTGGCCAGGCTTAAGTATGAACTACCGATAATAAAGGAAACGTATACTAAATCAAAAATAGGCGAACAACAAGGTC
CTTTAGGAGCTGGAACGTATGGAGTAGAATCTACAATAAAATTTTATAAAAGAAGAATCAATAAACTTATGAAGGAATTA
GAAAATATAAAGGCCTTTAAAGAAAAATCCATAGAATCTAATAAGAGGAACAATATTCCTTCTGTTGGAATCGTAGGATA
CACAAACTCCGGAAAGACCTCGTTATTTAACTCATTAACCGGGTTAACACAGAAAGTTGATACAAAACTATTTACCACAA
TGTCACCTAAAAGATATGCCCTCTCTATAAATAATAGAAAGATTATGCTAGTTGATACTGTAGGATTTATTAGAGGAATT
CCACCACAAATTGTAGATGCTTTCTTCGTCACTCTGTCAGAAGCAAAATACTCAGATGCATTAATTCTTGTAATAGATTC
TATGTTTTCGGAAAATTTACTAATTGAGACTTTGCAATCCTCTTTCGAAATTTTAAGAGAAATAGGAGTTTCGGGTAAGC
CTATACTAGTAGCCCTTAATAAAATTGATAAAATTGATGGCGATTTATATAAAAAGCTTAATCTAATAGAAAAGCTATCA
AAAGAGTTATACTCCCCCATATTCGATGTCATACCTATATCAGCTTTAAAGAGAACAAATCTTGAATTATTAAGGGAGAG
GATATACCAGCTAACAACACAGTTGAGTTGA

Upstream 100 bases:

>100_bases
TTAAGCTAGTTACCCCATTAGAAAATGAAGAAAGCGAGAAAGAATTCGATGAAACAGAATTAACCTTAGGGGATGTAGTT
AATATTAAAGAGGGAAAGAA

Downstream 100 bases:

>100_bases
AAGATATATATGTTTTAAGGTTAGGCCATAGACCAGCTAGAGATAAAAGAGTGACAACACATGTAATCTTAGTAGCAAGA
GCTTTCGGAGCTAAGGGTGT

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKSAVLFVSEEFKEEAIALVEGANYKIVRIYKLPKSPNVKFYIQYDKLQQIKNDEEISTLIVFEQLKPRHFINLRKELKG
KEILDKILLLLEIFALHAGSKEAKMQIELARLKYELPIIKETYTKSKIGEQQGPLGAGTYGVESTIKFYKRRINKLMKEL
ENIKAFKEKSIESNKRNNIPSVGIVGYTNSGKTSLFNSLTGLTQKVDTKLFTTMSPKRYALSINNRKIMLVDTVGFIRGI
PPQIVDAFFVTLSEAKYSDALILVIDSMFSENLLIETLQSSFEILREIGVSGKPILVALNKIDKIDGDLYKKLNLIEKLS
KELYSPIFDVIPISALKRTNLELLRERIYQLTTQLS

Sequences:

>Translated_356_residues
MKSAVLFVSEEFKEEAIALVEGANYKIVRIYKLPKSPNVKFYIQYDKLQQIKNDEEISTLIVFEQLKPRHFINLRKELKG
KEILDKILLLLEIFALHAGSKEAKMQIELARLKYELPIIKETYTKSKIGEQQGPLGAGTYGVESTIKFYKRRINKLMKEL
ENIKAFKEKSIESNKRNNIPSVGIVGYTNSGKTSLFNSLTGLTQKVDTKLFTTMSPKRYALSINNRKIMLVDTVGFIRGI
PPQIVDAFFVTLSEAKYSDALILVIDSMFSENLLIETLQSSFEILREIGVSGKPILVALNKIDKIDGDLYKKLNLIEKLS
KELYSPIFDVIPISALKRTNLELLRERIYQLTTQLS
>Mature_356_residues
MKSAVLFVSEEFKEEAIALVEGANYKIVRIYKLPKSPNVKFYIQYDKLQQIKNDEEISTLIVFEQLKPRHFINLRKELKG
KEILDKILLLLEIFALHAGSKEAKMQIELARLKYELPIIKETYTKSKIGEQQGPLGAGTYGVESTIKFYKRRINKLMKEL
ENIKAFKEKSIESNKRNNIPSVGIVGYTNSGKTSLFNSLTGLTQKVDTKLFTTMSPKRYALSINNRKIMLVDTVGFIRGI
PPQIVDAFFVTLSEAKYSDALILVIDSMFSENLLIETLQSSFEILREIGVSGKPILVALNKIDKIDGDLYKKLNLIEKLS
KELYSPIFDVIPISALKRTNLELLRERIYQLTTQLS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=219, Percent_Identity=27.3972602739726, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI310133118, Length=219, Percent_Identity=27.3972602739726, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI310124269, Length=219, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI310124267, Length=219, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI310124171, Length=219, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI310124169, Length=219, Percent_Identity=27.3972602739726, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790615, Length=349, Percent_Identity=28.3667621776504, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17561038, Length=237, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650079, Length=366, Percent_Identity=26.775956284153, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 40652; Mature: 40652

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVLFVSEEFKEEAIALVEGANYKIVRIYKLPKSPNVKFYIQYDKLQQIKNDEEISTL
CCCEEEEHHHHHHHHHHHHEECCCEEEEEEEECCCCCCEEEEEEEHHHHHHCCCCHHHHH
IVFEQLKPRHFINLRKELKGKEILDKILLLLEIFALHAGSKEAKMQIELARLKYELPIIK
EEHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEHHHHCCCCCHH
ETYTKSKIGEQQGPLGAGTYGVESTIKFYKRRINKLMKELENIKAFKEKSIESNKRNNIP
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SVGIVGYTNSGKTSLFNSLTGLTQKVDTKLFTTMSPKRYALSINNRKIMLVDTVGFIRGI
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECHHHHHCC
PPQIVDAFFVTLSEAKYSDALILVIDSMFSENLLIETLQSSFEILREIGVSGKPILVALN
CHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEH
KIDKIDGDLYKKLNLIEKLSKELYSPIFDVIPISALKRTNLELLRERIYQLTTQLS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSAVLFVSEEFKEEAIALVEGANYKIVRIYKLPKSPNVKFYIQYDKLQQIKNDEEISTL
CCCEEEEHHHHHHHHHHHHEECCCEEEEEEEECCCCCCEEEEEEEHHHHHHCCCCHHHHH
IVFEQLKPRHFINLRKELKGKEILDKILLLLEIFALHAGSKEAKMQIELARLKYELPIIK
EEHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEHHHHCCCCCHH
ETYTKSKIGEQQGPLGAGTYGVESTIKFYKRRINKLMKELENIKAFKEKSIESNKRNNIP
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SVGIVGYTNSGKTSLFNSLTGLTQKVDTKLFTTMSPKRYALSINNRKIMLVDTVGFIRGI
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEECHHHHHCC
PPQIVDAFFVTLSEAKYSDALILVIDSMFSENLLIETLQSSFEILREIGVSGKPILVALN
CHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEH
KIDKIDGDLYKKLNLIEKLSKELYSPIFDVIPISALKRTNLELLRERIYQLTTQLS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]