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The map label for this gene is 227827675

Identifier: 227827675

GI number: 227827675

Start: 1324820

End: 1325521

Strand: Direct

Name: 227827675

Synonym: M1425_1404

Alternate gene names: NA

Gene position: 1324820-1325521 (Clockwise)

Preceding gene: 227827674

Following gene: 227827676

Centisome position: 50.78

GC content: 34.9

Gene sequence:

>702_bases
ATGACGAAGGAGCGTGATTATGTAGTAGTTAAATATGACTCACATGGAGAGAGGTTTGAGATATTAGCTAAGCCAAAAGA
AGCATTAGCTTTTAGAAGTGGGAAGAGCATAAGTCTTTCTGATGTAGTAGTTTCTGACACTATTTATAAGGACGTGAAGA
AAGGTTTGAAAGCATCTCCAGCATCACTCAAAAAAGTTTTTGGTACTACTGATTTCGAGACAATTGTAAAAGAAATTTTA
CTTAAAGGTGAATTACCGGTAACTGCAGAACAAAGGAAAGAGATGTTAGAAACTAAGAGAAAGCAAATAATTGATTTTAT
TCATAGAAACGCCGTTGATCCCAAAACTAATTTACCAATTCCGCCAACTAGATTAGAGATGGCAATGGAACAAGCTAGAA
TACAAATCGATTTAAACAAAGACGTGGAGGCACAAGCTATGCAAATAGTAAAGGAGATTTCTAAGATAATTCCAATTAAA
ATAGCGAGAGCTCTGCTTAGTATTAAAGTACCATCAGAATATAGCTCTAAGGTTAGATCACAATTACATAACTTAGGGGA
GGTAAAAAAAGCCAATTGGTTAGAAGATGGTACATTATTAGCTGAATTGGAAATACCAGCGGGTGCACAGCAAGACGTTA
TAGATAAGTTAAATAATCTGACAAAAGGAGAAGTTGAAGTTAAAGTATTGCAAGTGAGATAG

Upstream 100 bases:

>100_bases
AAATAGGATACGCCTCAACCCAAACTGGGCTATTTCTAAAAATGACCAGTGAAGATAAGAATATGTATTTACAGAAGTTA
TAATAAGGTGGATTTTTTTT

Downstream 100 bases:

>100_bases
AAATGAGTCAGTCCCAGAAAATTGTTTTACAACCAAGATCAATAGTAGTGCCTGGCGAGTTATTAGCTGAAGGCGAGTTC
CAGATTCCTTGGTCTCCTTA

Product: RNA-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTKERDYVVVKYDSHGERFEILAKPKEALAFRSGKSISLSDVVVSDTIYKDVKKGLKASPASLKKVFGTTDFETIVKEIL
LKGELPVTAEQRKEMLETKRKQIIDFIHRNAVDPKTNLPIPPTRLEMAMEQARIQIDLNKDVEAQAMQIVKEISKIIPIK
IARALLSIKVPSEYSSKVRSQLHNLGEVKKANWLEDGTLLAELEIPAGAQQDVIDKLNNLTKGEVEVKVLQVR

Sequences:

>Translated_233_residues
MTKERDYVVVKYDSHGERFEILAKPKEALAFRSGKSISLSDVVVSDTIYKDVKKGLKASPASLKKVFGTTDFETIVKEIL
LKGELPVTAEQRKEMLETKRKQIIDFIHRNAVDPKTNLPIPPTRLEMAMEQARIQIDLNKDVEAQAMQIVKEISKIIPIK
IARALLSIKVPSEYSSKVRSQLHNLGEVKKANWLEDGTLLAELEIPAGAQQDVIDKLNNLTKGEVEVKVLQVR
>Mature_232_residues
TKERDYVVVKYDSHGERFEILAKPKEALAFRSGKSISLSDVVVSDTIYKDVKKGLKASPASLKKVFGTTDFETIVKEILL
KGELPVTAEQRKEMLETKRKQIIDFIHRNAVDPKTNLPIPPTRLEMAMEQARIQIDLNKDVEAQAMQIVKEISKIIPIKI
ARALLSIKVPSEYSSKVRSQLHNLGEVKKANWLEDGTLLAELEIPAGAQQDVIDKLNNLTKGEVEVKVLQVR

Specific function: Unknown

COG id: COG1500

COG function: function code J; Predicted exosome subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SDO1/SBDS family [H]

Homologues:

Organism=Homo sapiens, GI28416940, Length=163, Percent_Identity=30.0613496932515, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI25144459, Length=229, Percent_Identity=24.8908296943231, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323050, Length=156, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24659572, Length=213, Percent_Identity=28.169014084507, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR018978
- InterPro:   IPR018023
- InterPro:   IPR019783
- InterPro:   IPR002140 [H]

Pfam domain/function: PF01172 SBDS; PF09377 SBDS_C [H]

EC number: NA

Molecular weight: Translated: 26227; Mature: 26096

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKERDYVVVKYDSHGERFEILAKPKEALAFRSGKSISLSDVVVSDTIYKDVKKGLKASP
CCCCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
ASLKKVFGTTDFETIVKEILLKGELPVTAEQRKEMLETKRKQIIDFIHRNAVDPKTNLPI
HHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PPTRLEMAMEQARIQIDLNKDVEAQAMQIVKEISKIIPIKIARALLSIKVPSEYSSKVRS
CHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QLHNLGEVKKANWLEDGTLLAELEIPAGAQQDVIDKLNNLTKGEVEVKVLQVR
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEEEC
>Mature Secondary Structure 
TKERDYVVVKYDSHGERFEILAKPKEALAFRSGKSISLSDVVVSDTIYKDVKKGLKASP
CCCCCEEEEEECCCCCEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
ASLKKVFGTTDFETIVKEILLKGELPVTAEQRKEMLETKRKQIIDFIHRNAVDPKTNLPI
HHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PPTRLEMAMEQARIQIDLNKDVEAQAMQIVKEISKIIPIKIARALLSIKVPSEYSSKVRS
CHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QLHNLGEVKKANWLEDGTLLAELEIPAGAQQDVIDKLNNLTKGEVEVKVLQVR
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]