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The map label for this gene is mdtA [H]

Identifier: 227081826

GI number: 227081826

Start: 1757109

End: 1758140

Strand: Reverse

Name: mdtA [H]

Synonym: VCM66_1615

Alternate gene names: 227081826

Gene position: 1758140-1757109 (Counterclockwise)

Preceding gene: 227081827

Following gene: 227081825

Centisome position: 60.78

GC content: 51.07

Gene sequence:

>1032_bases
ATGAACAAAACCCTTTTGGCCTTTTCTATCTGCTCCACTTTGCTGGTGGGGTGTGGAAAAGAGCTTCCTCCCGTGCCTGA
GCCCGATTCGCGGCCAGCTAAATTGACGACTGTGTCCGTAGGTAACAACACCTTTTCTCGCCAATTTCCAGCCACTACGG
CGGCTGGCGATCGCGCGGTGCTCGCTTTCCGTGTACCCGGACAACTACAAACCATTGATGTTTTAGCCGGACAAGAGGTG
AAGAAAGGTGAGGTACTTGCCAGACTCAACCCTGACGAATATGCGTTGTTAGAACAGCAAGCCAGCGCCAATTTTCAATT
AGCCGATGTGCAATTTCAGCGGGCACAGCGATTACGACAAGACAAAGTCGTTTCCGAGCAGGATTTCGACCAAGCTCAAG
CCAATCACAATTCCGCGAAAGCCACCTGGGAACAAGCCAAAGCCAATCTGCGTTATACCCAATTGATCGCCCCTTATGAT
GGCACTATTTCGCTGATCCCAGCAGAGCAGTATGAGTATGTCGCAGCCAAGCAAGGGGTGATGAATATTCAAACCAATCA
ACTGCTCAAAGTGCAGTTTCTCCTTCCCGATCATTTGCTTAATCGCTTTTCTCGCGATGGTGTAGAAGCGCATATGGTGT
TTGACTCGTTCCCTAACCGCCAATATCCGTTGCAATTTCAAGAGATAGATACCGAGGCCGATTCCAAAACCCGCTCCTAT
AAAGTGACTATGGTGATGGAAAGACCCAATGATGTCGGCATTTTGCCGGGTATGGCGGGGCGTGTAAGCCTCATGGCTCC
GAGCGGTAGCGCGACGGTGATCCCCACTTCTGCATTGTTTGCAGAGCAAGGGGGAAAATACGTATGGCGAGTCGATGACG
CGGGGCTGGTCAGTAAAGCTGCGGTCACTTTGAATGAACAACGCCAAGTGCTTACAGGCTTAAATGATGGCGACCGGATC
ATTATTTCCGGTGTCAGTGGCGTGACCGAGGGCATAAAAGTGCGTGAATGGGTCAAGGAGCGAGGGCTGTAG

Upstream 100 bases:

>100_bases
TCTCACTTTCGCTAATATTTGGTGAAAAATCGATGGCGCGAGTGGAGTTAACGCACTGATTCACCTATGTTTGAGCTATG
TCTAAGCATAGGTAATTGGT

Downstream 100 bases:

>100_bases
GATGAAAATAATTCGTTACACCGCTTGGTTGGCTCACTTACTGTTGATCGCAGGATGCAGTGAACCCACGAAGCTCGAAC
GCGATACGCTACCGCGAGTA

Product: putative multidrug resistance protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNKTLLAFSICSTLLVGCGKELPPVPEPDSRPAKLTTVSVGNNTFSRQFPATTAAGDRAVLAFRVPGQLQTIDVLAGQEV
KKGEVLARLNPDEYALLEQQASANFQLADVQFQRAQRLRQDKVVSEQDFDQAQANHNSAKATWEQAKANLRYTQLIAPYD
GTISLIPAEQYEYVAAKQGVMNIQTNQLLKVQFLLPDHLLNRFSRDGVEAHMVFDSFPNRQYPLQFQEIDTEADSKTRSY
KVTMVMERPNDVGILPGMAGRVSLMAPSGSATVIPTSALFAEQGGKYVWRVDDAGLVSKAAVTLNEQRQVLTGLNDGDRI
IISGVSGVTEGIKVREWVKERGL

Sequences:

>Translated_343_residues
MNKTLLAFSICSTLLVGCGKELPPVPEPDSRPAKLTTVSVGNNTFSRQFPATTAAGDRAVLAFRVPGQLQTIDVLAGQEV
KKGEVLARLNPDEYALLEQQASANFQLADVQFQRAQRLRQDKVVSEQDFDQAQANHNSAKATWEQAKANLRYTQLIAPYD
GTISLIPAEQYEYVAAKQGVMNIQTNQLLKVQFLLPDHLLNRFSRDGVEAHMVFDSFPNRQYPLQFQEIDTEADSKTRSY
KVTMVMERPNDVGILPGMAGRVSLMAPSGSATVIPTSALFAEQGGKYVWRVDDAGLVSKAAVTLNEQRQVLTGLNDGDRI
IISGVSGVTEGIKVREWVKERGL
>Mature_343_residues
MNKTLLAFSICSTLLVGCGKELPPVPEPDSRPAKLTTVSVGNNTFSRQFPATTAAGDRAVLAFRVPGQLQTIDVLAGQEV
KKGEVLARLNPDEYALLEQQASANFQLADVQFQRAQRLRQDKVVSEQDFDQAQANHNSAKATWEQAKANLRYTQLIAPYD
GTISLIPAEQYEYVAAKQGVMNIQTNQLLKVQFLLPDHLLNRFSRDGVEAHMVFDSFPNRQYPLQFQEIDTEADSKTRSY
KVTMVMERPNDVGILPGMAGRVSLMAPSGSATVIPTSALFAEQGGKYVWRVDDAGLVSKAAVTLNEQRQVLTGLNDGDRI
IISGVSGVTEGIKVREWVKERGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=313, Percent_Identity=25.2396166134185, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081796, Length=301, Percent_Identity=29.2358803986711, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789929, Length=387, Percent_Identity=24.5478036175711, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37739; Mature: 37739

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTLLAFSICSTLLVGCGKELPPVPEPDSRPAKLTTVSVGNNTFSRQFPATTAAGDRAV
CCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEE
LAFRVPGQLQTIDVLAGQEVKKGEVLARLNPDEYALLEQQASANFQLADVQFQRAQRLRQ
EEEECCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEEHHHHHHHHHHHH
DKVVSEQDFDQAQANHNSAKATWEQAKANLRYTQLIAPYDGTISLIPAEQYEYVAAKQGV
HCCCCCCCHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCC
MNIQTNQLLKVQFLLPDHLLNRFSRDGVEAHMVFDSFPNRQYPLQFQEIDTEADSKTRSY
EEECCCCEEEEEEECCHHHHHHHCCCCCEEEEEEECCCCCCCCEEHEECCCCCCCCCCEE
KVTMVMERPNDVGILPGMAGRVSLMAPSGSATVIPTSALFAEQGGKYVWRVDDAGLVSKA
EEEEEEECCCCCEECCCCCCEEEEECCCCCCEEEECHHHHHHCCCCEEEEECCCCCHHHE
AVTLNEQRQVLTGLNDGDRIIISGVSGVTEGIKVREWVKERGL
EEEECHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKTLLAFSICSTLLVGCGKELPPVPEPDSRPAKLTTVSVGNNTFSRQFPATTAAGDRAV
CCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEE
LAFRVPGQLQTIDVLAGQEVKKGEVLARLNPDEYALLEQQASANFQLADVQFQRAQRLRQ
EEEECCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEEHHHHHHHHHHHH
DKVVSEQDFDQAQANHNSAKATWEQAKANLRYTQLIAPYDGTISLIPAEQYEYVAAKQGV
HCCCCCCCHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCC
MNIQTNQLLKVQFLLPDHLLNRFSRDGVEAHMVFDSFPNRQYPLQFQEIDTEADSKTRSY
EEECCCCEEEEEEECCHHHHHHHCCCCCEEEEEEECCCCCCCCEEHEECCCCCCCCCCEE
KVTMVMERPNDVGILPGMAGRVSLMAPSGSATVIPTSALFAEQGGKYVWRVDDAGLVSKA
EEEEEEECCCCCEECCCCCCEEEEECCCCCCEEEECHHHHHHCCCCEEEEECCCCCHHHE
AVTLNEQRQVLTGLNDGDRIIISGVSGVTEGIKVREWVKERGL
EEEECHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA