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The map label for this gene is alr2 [H]

Identifier: 227081483

GI number: 227081483

Start: 1351165

End: 1352451

Strand: Reverse

Name: alr2 [H]

Synonym: VCM66_1267

Alternate gene names: 227081483

Gene position: 1352451-1351165 (Counterclockwise)

Preceding gene: 227081484

Following gene: 227081482

Centisome position: 46.76

GC content: 49.49

Gene sequence:

>1287_bases
TTGGAGCAGCCGCTTCTCAGTCGCAAGAAGAATGTTCCATCAATGATAACCACAGGAGATATCATGCATTTTAAAGCCAC
GCTGCTTTCTCTCTCTATCGCGGCGACTTTGCCTTCTTTCTCTCTCTCTGCTGCGCCATTACACATCGACACCGCTTTAC
CGGATGCCGCTCAAATTCAGCAAAGTAATTCTTGGCTGGAGATTAGCTTAGGCCAATTCCAAAGCAACATTGAACAATTC
AAATCACACATGAACGCCAACACCAAAATTTGCGCCATCATGAAAGCCGACGCTTACGGTAACGGTATTCGTGGTTTAAT
GCCGACCATTATCGCGCAAGGCATTCCTTGTGTGGGGGTGGCAAGTAATGCAGAGGCGCGTGCGGTGCGTGAAAGTGGCT
TTAAAGGTGAACTGATCCGTGTGCGCTCTGCCAGCCTAAGTGAAATGTCCTCGGCACTCGATCTCAATATCGAAGAGCTG
ATTGGTACCCACCAACAAGCCCTCGATCTGGCGGAGCTTGCCAAACAAAGTGGTAAAACGCTCAAAGTTCACATCGCGCT
GAATGACGGCGGCATGGGCCGTAACGGCATTGATATGACCACGGAAGCCGGCAAGAAAGAAGCCGTCTCTATTGCGACTC
AACCTTCGTTGAGTGTCGTTGGCATTATGACCCACTTCCCGAATTACAATGCGGACGAAGTGCGCGCAAAACTGGCTCAA
TTCAAAGAGAGCTCAACTTGGCTAATGCAACAAGCCAATTTGAAACGTGAAGAGATCACACTGCATGTTGCGAACTCTTA
CACCGCGCTCAATGTGCCAGAAGCACAACTGGACATGGTTCGTCCAGGTGGCGTGTTGTTTGGTGATTTGCCAACCAACC
CTGAATACCCATCGATTGTTTCTTTCAAAACACGTGTGTCTTCGCTGCACCATTTGCCAAAGGACTCAACTGTGGGTTAT
GACAGTACTTTTACTACCAGCCGTGACAGTGTGCTGGCGAACCTGCCTGTGGGTTATTCTGATGGTTACCCGCGCAAAAT
GGGCAATAAAGCCGAAGTGCTGATCAATGGACAACGCGCCAAAGTCGTGGGAGTGACATCGATGAACACCACTGTGGTTG
ATGTGACCGAGATTAAGGGCGTGCTCCCCGGTCAAGAAGTGGTTCTGTTTGGTCAGCAACAGAAGCAAAGCATCGCGGTC
AGTGAGATGGAAAACAACGCTGAGCTGATTTTCCCTGAGTTGTATACGCTGTGGGGAACCAGTAACCCACGTTTCTACGT
GAAATAA

Upstream 100 bases:

>100_bases
TCAGCTCGCGGTTTCGCTACAAGATACACTACGCCGATTTAAGATTCGTTAATTTTCACGCTACCTACAGGGCGGCGTCT
TTCTCTATTCTTCTTGCGAC

Downstream 100 bases:

>100_bases
GCTATACCCAAACAACTTGGAGAAACCACCCAATCGAGGTGGGCGCATACGCCCACCTATCTCCACAGACCTTTTTACGG
CATAATCTCTTCGCACTTTC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MEQPLLSRKKNVPSMITTGDIMHFKATLLSLSIAATLPSFSLSAAPLHIDTALPDAAQIQQSNSWLEISLGQFQSNIEQF
KSHMNANTKICAIMKADAYGNGIRGLMPTIIAQGIPCVGVASNAEARAVRESGFKGELIRVRSASLSEMSSALDLNIEEL
IGTHQQALDLAELAKQSGKTLKVHIALNDGGMGRNGIDMTTEAGKKEAVSIATQPSLSVVGIMTHFPNYNADEVRAKLAQ
FKESSTWLMQQANLKREEITLHVANSYTALNVPEAQLDMVRPGGVLFGDLPTNPEYPSIVSFKTRVSSLHHLPKDSTVGY
DSTFTTSRDSVLANLPVGYSDGYPRKMGNKAEVLINGQRAKVVGVTSMNTTVVDVTEIKGVLPGQEVVLFGQQQKQSIAV
SEMENNAELIFPELYTLWGTSNPRFYVK

Sequences:

>Translated_428_residues
MEQPLLSRKKNVPSMITTGDIMHFKATLLSLSIAATLPSFSLSAAPLHIDTALPDAAQIQQSNSWLEISLGQFQSNIEQF
KSHMNANTKICAIMKADAYGNGIRGLMPTIIAQGIPCVGVASNAEARAVRESGFKGELIRVRSASLSEMSSALDLNIEEL
IGTHQQALDLAELAKQSGKTLKVHIALNDGGMGRNGIDMTTEAGKKEAVSIATQPSLSVVGIMTHFPNYNADEVRAKLAQ
FKESSTWLMQQANLKREEITLHVANSYTALNVPEAQLDMVRPGGVLFGDLPTNPEYPSIVSFKTRVSSLHHLPKDSTVGY
DSTFTTSRDSVLANLPVGYSDGYPRKMGNKAEVLINGQRAKVVGVTSMNTTVVDVTEIKGVLPGQEVVLFGQQQKQSIAV
SEMENNAELIFPELYTLWGTSNPRFYVK
>Mature_428_residues
MEQPLLSRKKNVPSMITTGDIMHFKATLLSLSIAATLPSFSLSAAPLHIDTALPDAAQIQQSNSWLEISLGQFQSNIEQF
KSHMNANTKICAIMKADAYGNGIRGLMPTIIAQGIPCVGVASNAEARAVRESGFKGELIRVRSASLSEMSSALDLNIEEL
IGTHQQALDLAELAKQSGKTLKVHIALNDGGMGRNGIDMTTEAGKKEAVSIATQPSLSVVGIMTHFPNYNADEVRAKLAQ
FKESSTWLMQQANLKREEITLHVANSYTALNVPEAQLDMVRPGGVLFGDLPTNPEYPSIVSFKTRVSSLHHLPKDSTVGY
DSTFTTSRDSVLANLPVGYSDGYPRKMGNKAEVLINGQRAKVVGVTSMNTTVVDVTEIKGVLPGQEVVLFGQQQKQSIAV
SEMENNAELIFPELYTLWGTSNPRFYVK

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=344, Percent_Identity=26.1627906976744, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790487, Length=342, Percent_Identity=25.1461988304094, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 46408; Mature: 46408

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQPLLSRKKNVPSMITTGDIMHFKATLLSLSIAATLPSFSLSAAPLHIDTALPDAAQIQ
CCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHH
QSNSWLEISLGQFQSNIEQFKSHMNANTKICAIMKADAYGNGIRGLMPTIIAQGIPCVGV
CCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEE
ASNAEARAVRESGFKGELIRVRSASLSEMSSALDLNIEELIGTHQQALDLAELAKQSGKT
CCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCE
LKVHIALNDGGMGRNGIDMTTEAGKKEAVSIATQPSLSVVGIMTHFPNYNADEVRAKLAQ
EEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHH
FKESSTWLMQQANLKREEITLHVANSYTALNVPEAQLDMVRPGGVLFGDLPTNPEYPSIV
HCCCCHHHHHHCCCCCEEEEEEEECCEEEECCCHHHHEEECCCCEEECCCCCCCCCCCEE
SFKTRVSSLHHLPKDSTVGYDSTFTTSRDSVLANLPVGYSDGYPRKMGNKAEVLINGQRA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHCCCCEEEEEECCEE
KVVGVTSMNTTVVDVTEIKGVLPGQEVVLFGQQQKQSIAVSEMENNAELIFPELYTLWGT
EEEEEEECCCEEEEHHHHCCCCCCCEEEEECCCCCHHEEHHHCCCCCEEEECCCEEEECC
SNPRFYVK
CCCEEEEC
>Mature Secondary Structure
MEQPLLSRKKNVPSMITTGDIMHFKATLLSLSIAATLPSFSLSAAPLHIDTALPDAAQIQ
CCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHH
QSNSWLEISLGQFQSNIEQFKSHMNANTKICAIMKADAYGNGIRGLMPTIIAQGIPCVGV
CCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEE
ASNAEARAVRESGFKGELIRVRSASLSEMSSALDLNIEELIGTHQQALDLAELAKQSGKT
CCCCHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCCE
LKVHIALNDGGMGRNGIDMTTEAGKKEAVSIATQPSLSVVGIMTHFPNYNADEVRAKLAQ
EEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHH
FKESSTWLMQQANLKREEITLHVANSYTALNVPEAQLDMVRPGGVLFGDLPTNPEYPSIV
HCCCCHHHHHHCCCCCEEEEEEEECCEEEECCCHHHHEEECCCCEEECCCCCCCCCCCEE
SFKTRVSSLHHLPKDSTVGYDSTFTTSRDSVLANLPVGYSDGYPRKMGNKAEVLINGQRA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHCCCCEEEEEECCEE
KVVGVTSMNTTVVDVTEIKGVLPGQEVVLFGQQQKQSIAVSEMENNAELIFPELYTLWGT
EEEEEEECCCEEEEHHHHCCCCCCCEEEEECCCCCHHEEHHHCCCCCEEEECCCEEEECC
SNPRFYVK
CCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]