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The map label for this gene is trpD [H]

Identifier: 227081344

GI number: 227081344

Start: 1203139

End: 1204200

Strand: Reverse

Name: trpD [H]

Synonym: VCM66_1127

Alternate gene names: 227081344

Gene position: 1204200-1203139 (Counterclockwise)

Preceding gene: 227081345

Following gene: 227081343

Centisome position: 41.63

GC content: 52.17

Gene sequence:

>1062_bases
TTGGGCATTGTCTTCAACGCCAGCGCAGACTCAATTCGCGTAACCGCACAGGGAGAGAATGTTATGCAAACCATTATTAA
TAAACTCTATGAACAGCAAGGGCTCACGCAAGCCGAGAGCCAACAGCTTTTCGACCAAATTATTCGCGGTGAAATGGATC
CTGTATTGATGGCGGCGGTACTGACTGCACTGAAAATCAAAGGCGAAACGCCAGATGAAATCGCGGGTGCGGCTAAAGCC
CTGCTCGCCAACGCCAATCCATTTCCGCGTCCTGATTACGACTTTGCCGATATCGTCGGTACCGGTGGCGATGGCTCAAA
CACCATCAACATCTCAACCACCGCCGCATTTGTCGCCGCAGCGTGTGGCGTGAAAGTCGCCAAACACGGCAACCGTGGGG
TATCGAGCAAATCCGGCTCTTCCGATCTGCTCAGCTCATTTGGGATCAACCTTGCCATGAGCGCGCAAGATTCGCGCCAA
GCCTTGGATGATCTCGGTGTCGCTTTCTTGTTTGCCCCTCAGTATCACGGCGGTGTGCGCCATGCGATGCCGGTGCGTCA
AACCATGAAAACTCGCACCATTTTCAACATCTTAGGCCCCCTGATTAACCCTGCTCGTCCCAATATTGAATTGATGGGGG
TTTACAGCAAGGATTTGGTTCGTCCTATTGCGCAAACCATGTTACAAATGGGTCTGAAACGCGCAGCGGTGGTGCATGGT
TCAGGTCTTGATGAAGTCGCGATTCATGGCGAAACGCAAGTAGCAGAAATTCGCCAAGGCGAATTGATTGAATACACGCT
CACTCCGGAAGATTTTGGTGTTAGCCGTTACCCACTGGATGCGATCCGTGGTGGAGAGCCAGAAGAGAATCGCGCCATCA
TCACCCAGATCCTAACGGGCAATGGCACAGCAGCACAAATGGCGGCAGTGGCAGTCAACGTTGCACTTCTGCTGCGTCTA
TTTGGTCAAGAAGATCTGAAAGCCAACACCCAACAAGCGATCGCCGTGATGAAATCGGGCCAAGCCTATGGATTGGTTCA
GCAGTTAGCACAACGAGGTTAA

Upstream 100 bases:

>100_bases
TGTCGGTGGTTAATGAGGCTGACAAAGTCTGCGGCTTTCAATTTCACCCAGAATCGATCATGACCACCCACGGCGCTACC
TTGCTGGCCAATGCCATTGA

Downstream 100 bases:

>100_bases
GCAGAATGTCCGAGCAGTTGTCTGAGCATATTTCCGTACAAACCGCGCAAATGGCGCAAGTGCTGGTCAAAATCGTCAAC
GATAAATACCAATGGATTGA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MGIVFNASADSIRVTAQGENVMQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAVLTALKIKGETPDEIAGAAKA
LLANANPFPRPDYDFADIVGTGGDGSNTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSSDLLSSFGINLAMSAQDSRQ
ALDDLGVAFLFAPQYHGGVRHAMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHG
SGLDEVAIHGETQVAEIRQGELIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTGNGTAAQMAAVAVNVALLLRL
FGQEDLKANTQQAIAVMKSGQAYGLVQQLAQRG

Sequences:

>Translated_353_residues
MGIVFNASADSIRVTAQGENVMQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAVLTALKIKGETPDEIAGAAKA
LLANANPFPRPDYDFADIVGTGGDGSNTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSSDLLSSFGINLAMSAQDSRQ
ALDDLGVAFLFAPQYHGGVRHAMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHG
SGLDEVAIHGETQVAEIRQGELIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTGNGTAAQMAAVAVNVALLLRL
FGQEDLKANTQQAIAVMKSGQAYGLVQQLAQRG
>Mature_352_residues
GIVFNASADSIRVTAQGENVMQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAVLTALKIKGETPDEIAGAAKAL
LANANPFPRPDYDFADIVGTGGDGSNTINISTTAAFVAAACGVKVAKHGNRGVSSKSGSSDLLSSFGINLAMSAQDSRQA
LDDLGVAFLFAPQYHGGVRHAMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHGS
GLDEVAIHGETQVAEIRQGELIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTGNGTAAQMAAVAVNVALLLRLF
GQEDLKANTQQAIAVMKSGQAYGLVQQLAQRG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=334, Percent_Identity=64.0718562874251, Blast_Score=411, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6320561, Length=314, Percent_Identity=32.1656050955414, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37532; Mature: 37401

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIVFNASADSIRVTAQGENVMQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAV
CCEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHH
LTALKIKGETPDEIAGAAKALLANANPFPRPDYDFADIVGTGGDGSNTINISTTAAFVAA
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHEECCCCCCCEEEEHHHHHHHHH
ACGVKVAKHGNRGVSSKSGSSDLLSSFGINLAMSAQDSRQALDDLGVAFLFAPQYHGGVR
HHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEECCCHHHHHHHHCCEEEEECCCCCCCCH
HAMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEC
SGLDEVAIHGETQVAEIRQGELIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTG
CCCCCEEECCCCHHHHHCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECC
NGTAAQMAAVAVNVALLLRLFGQEDLKANTQQAIAVMKSGQAYGLVQQLAQRG
CCHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GIVFNASADSIRVTAQGENVMQTIINKLYEQQGLTQAESQQLFDQIIRGEMDPVLMAAV
CEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHH
LTALKIKGETPDEIAGAAKALLANANPFPRPDYDFADIVGTGGDGSNTINISTTAAFVAA
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHEECCCCCCCEEEEHHHHHHHHH
ACGVKVAKHGNRGVSSKSGSSDLLSSFGINLAMSAQDSRQALDDLGVAFLFAPQYHGGVR
HHHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEECCCHHHHHHHHCCEEEEECCCCCCCCH
HAMPVRQTMKTRTIFNILGPLINPARPNIELMGVYSKDLVRPIAQTMLQMGLKRAAVVHG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEC
SGLDEVAIHGETQVAEIRQGELIEYTLTPEDFGVSRYPLDAIRGGEPEENRAIITQILTG
CCCCCEEECCCCHHHHHCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECC
NGTAAQMAAVAVNVALLLRLFGQEDLKANTQQAIAVMKSGQAYGLVQQLAQRG
CCHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA