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The map label for this gene is mreD [H]

Identifier: 227080628

GI number: 227080628

Start: 428859

End: 429347

Strand: Direct

Name: mreD [H]

Synonym: VCM66_0402

Alternate gene names: 227080628

Gene position: 428859-429347 (Clockwise)

Preceding gene: 227080627

Following gene: 227080629

Centisome position: 14.83

GC content: 49.28

Gene sequence:

>489_bases
ATGCTCAGCAGTGATATTAAAGGCCGCATGGTCATTCTTGCCTCATTTTTACTGGCGCTGATTTTGCAAACCATCCCATG
GCCGGGAACCTTAGATCTGTTCCGGCCACCTTGGCTGCTGCTGGTCTGTTGTTACTGGGTATTGGCACTGCCGCACCGAG
TGAATGTCGGCAGCGCTTTGGTCATGGGCTTATTGTGGGATCTGTTACTCGGTTCCACCTTAGGTATTCGCGGCATGATG
ATGTCGATCATCATCTATCTGGTCGCGATGAATTTCTTGGTACTGCGCAACATGGCTCTATGGCAGCAAGCGATTGTGAT
TGGTTTGCTGTCGATGGGATTGGAAGTGCTGATTTTCTGTGGTGAGTACCTGATCCAGAATGTGACATTCAATCCGTTGT
CACTCTGGAGTGGAGTGATTGCCTGTATACTTTGGCCGTGGATGTTTTTATTACTGCGCCGAGTTCGACGCCATTGGCAT
GTGAAATGA

Upstream 100 bases:

>100_bases
TTTGATCGCTTGCGCTACTTATTGCTGATTTGGCCAAACGAAGATCGCTTACAAAAAGTGATGCAGGCTGATCCGCAGGT
GCTATTAGAGGAAGAAGCCA

Downstream 100 bases:

>100_bases
CAATATCGAAATTAGTGTTGGCTTCGGGATCCCCTAGACGTCGTGAACTGCTCGCTCAAATGGGCTACCAGTTTGAAGTC
GTGGTTCCGAATGTCGAAGA

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MLSSDIKGRMVILASFLLALILQTIPWPGTLDLFRPPWLLLVCCYWVLALPHRVNVGSALVMGLLWDLLLGSTLGIRGMM
MSIIIYLVAMNFLVLRNMALWQQAIVIGLLSMGLEVLIFCGEYLIQNVTFNPLSLWSGVIACILWPWMFLLLRRVRRHWH
VK

Sequences:

>Translated_162_residues
MLSSDIKGRMVILASFLLALILQTIPWPGTLDLFRPPWLLLVCCYWVLALPHRVNVGSALVMGLLWDLLLGSTLGIRGMM
MSIIIYLVAMNFLVLRNMALWQQAIVIGLLSMGLEVLIFCGEYLIQNVTFNPLSLWSGVIACILWPWMFLLLRRVRRHWH
VK
>Mature_162_residues
MLSSDIKGRMVILASFLLALILQTIPWPGTLDLFRPPWLLLVCCYWVLALPHRVNVGSALVMGLLWDLLLGSTLGIRGMM
MSIIIYLVAMNFLVLRNMALWQQAIVIGLLSMGLEVLIFCGEYLIQNVTFNPLSLWSGVIACILWPWMFLLLRRVRRHWH
VK

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=162, Percent_Identity=53.7037037037037, Blast_Score=171, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18548; Mature: 18548

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSDIKGRMVILASFLLALILQTIPWPGTLDLFRPPWLLLVCCYWVLALPHRVNVGSAL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
VMGLLWDLLLGSTLGIRGMMMSIIIYLVAMNFLVLRNMALWQQAIVIGLLSMGLEVLIFC
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEYLIQNVTFNPLSLWSGVIACILWPWMFLLLRRVRRHWHVK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSSDIKGRMVILASFLLALILQTIPWPGTLDLFRPPWLLLVCCYWVLALPHRVNVGSAL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
VMGLLWDLLLGSTLGIRGMMMSIIIYLVAMNFLVLRNMALWQQAIVIGLLSMGLEVLIFC
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEYLIQNVTFNPLSLWSGVIACILWPWMFLLLRRVRRHWHVK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]