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The map label for this gene is mreC [H]

Identifier: 227080627

GI number: 227080627

Start: 427982

End: 428872

Strand: Direct

Name: mreC [H]

Synonym: VCM66_0401

Alternate gene names: 227080627

Gene position: 427982-428872 (Clockwise)

Preceding gene: 227080626

Following gene: 227080628

Centisome position: 14.8

GC content: 48.48

Gene sequence:

>891_bases
ATGAAACCTATCTTTGGTCGAGGACCTTCTCTGCAGCTACGGCTATTTTTTGCGGTTATGCTATCAGCCAGCCTTATGCT
GGCTGATAGTCGTTTAGGTGCATTCTCACATGTACGCTTTCTGCTCAATAGTCTGGTTGCGCCTATTCAGTACGCAGCGG
ATCTGCCGCGCGTACTGTTTGACGATTTTTATGACAGCATCAGCTCTCATCAGCAGTTACGGGAAAATAACCAACTGCTA
AAACGTGAAGTCCTGACCCTGAAAAGTAATCTGTTACTGCTTGAGCAGTACAAAGAAGAGAACCAACGGCTGCGTAAGTT
ACTCGGATCCTCCTTTTTGCGTGATGAGAAAAAGGTGGTGACCGAAGTGATGGCGGTCGATACGTCGCCCTATCGTCACC
AAGTTGTGATCGATAAAGGCCGGGTAGATGGAGTGTACGAAGGTCAGCCGATCATCAATGAAAAAGGCATTGTTGGACAA
GTCACCTTTGTGGCGGCGCACAATAGCCGAGTCTTGCTCCTGATTGACCCTAATACCGCGATTCCGGTACAGAACATTCG
CAATGATATTCGAGTCATCGCCTCAGGCAATGGACAAACCGATCAAATCCAACTGGAACATATACCTACCAGTACCGATA
TTGAAGTCGGCGATATGCTCGTCACCTCTGGCTTGGGTGGGGTTTACCCTGAAGGCTACCCAGTGGCGATTGTGTCACAG
GTGGATAAAGACACGCGCCGTGAGTTTGCCTCGATCAAAGCCGATCCTGTAGTAGAATTTGATCGCTTGCGCTACTTATT
GCTGATTTGGCCAAACGAAGATCGCTTACAAAAAGTGATGCAGGCTGATCCGCAGGTGCTATTAGAGGAAGAAGCCAATG
CTCAGCAGTGA

Upstream 100 bases:

>100_bases
AAATGATCGATATGCACGGCGGCGATCTGTTTAGCGAAGAATAAACCGTAGTGTTGTGCCTTATGCATGGCACTTTGCTC
AGAGTTAGGATGGTTATTGG

Downstream 100 bases:

>100_bases
TATTAAAGGCCGCATGGTCATTCTTGCCTCATTTTTACTGGCGCTGATTTTGCAAACCATCCCATGGCCGGGAACCTTAG
ATCTGTTCCGGCCACCTTGG

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKPIFGRGPSLQLRLFFAVMLSASLMLADSRLGAFSHVRFLLNSLVAPIQYAADLPRVLFDDFYDSISSHQQLRENNQLL
KREVLTLKSNLLLLEQYKEENQRLRKLLGSSFLRDEKKVVTEVMAVDTSPYRHQVVIDKGRVDGVYEGQPIINEKGIVGQ
VTFVAAHNSRVLLLIDPNTAIPVQNIRNDIRVIASGNGQTDQIQLEHIPTSTDIEVGDMLVTSGLGGVYPEGYPVAIVSQ
VDKDTRREFASIKADPVVEFDRLRYLLLIWPNEDRLQKVMQADPQVLLEEEANAQQ

Sequences:

>Translated_296_residues
MKPIFGRGPSLQLRLFFAVMLSASLMLADSRLGAFSHVRFLLNSLVAPIQYAADLPRVLFDDFYDSISSHQQLRENNQLL
KREVLTLKSNLLLLEQYKEENQRLRKLLGSSFLRDEKKVVTEVMAVDTSPYRHQVVIDKGRVDGVYEGQPIINEKGIVGQ
VTFVAAHNSRVLLLIDPNTAIPVQNIRNDIRVIASGNGQTDQIQLEHIPTSTDIEVGDMLVTSGLGGVYPEGYPVAIVSQ
VDKDTRREFASIKADPVVEFDRLRYLLLIWPNEDRLQKVMQADPQVLLEEEANAQQ
>Mature_296_residues
MKPIFGRGPSLQLRLFFAVMLSASLMLADSRLGAFSHVRFLLNSLVAPIQYAADLPRVLFDDFYDSISSHQQLRENNQLL
KREVLTLKSNLLLLEQYKEENQRLRKLLGSSFLRDEKKVVTEVMAVDTSPYRHQVVIDKGRVDGVYEGQPIINEKGIVGQ
VTFVAAHNSRVLLLIDPNTAIPVQNIRNDIRVIASGNGQTDQIQLEHIPTSTDIEVGDMLVTSGLGGVYPEGYPVAIVSQ
VDKDTRREFASIKADPVVEFDRLRYLLLIWPNEDRLQKVMQADPQVLLEEEANAQQ

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=306, Percent_Identity=52.2875816993464, Blast_Score=277, Evalue=5e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 33365; Mature: 33365

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIFGRGPSLQLRLFFAVMLSASLMLADSRLGAFSHVRFLLNSLVAPIQYAADLPRVLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHH
DDFYDSISSHQQLRENNQLLKREVLTLKSNLLLLEQYKEENQRLRKLLGSSFLRDEKKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEVMAVDTSPYRHQVVIDKGRVDGVYEGQPIINEKGIVGQVTFVAAHNSRVLLLIDPNTA
HHHHHCCCCCCEEEEEEECCCCCCEECCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCC
IPVQNIRNDIRVIASGNGQTDQIQLEHIPTSTDIEVGDMLVTSGLGGVYPEGYPVAIVSQ
CCHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEC
VDKDTRREFASIKADPVVEFDRLRYLLLIWPNEDRLQKVMQADPQVLLEEEANAQQ
CCHHHHHHHHHCCCCCCEECCCCEEEEEEECCHHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure
MKPIFGRGPSLQLRLFFAVMLSASLMLADSRLGAFSHVRFLLNSLVAPIQYAADLPRVLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHH
DDFYDSISSHQQLRENNQLLKREVLTLKSNLLLLEQYKEENQRLRKLLGSSFLRDEKKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEVMAVDTSPYRHQVVIDKGRVDGVYEGQPIINEKGIVGQVTFVAAHNSRVLLLIDPNTA
HHHHHCCCCCCEEEEEEECCCCCCEECCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCC
IPVQNIRNDIRVIASGNGQTDQIQLEHIPTSTDIEVGDMLVTSGLGGVYPEGYPVAIVSQ
CCHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEC
VDKDTRREFASIKADPVVEFDRLRYLLLIWPNEDRLQKVMQADPQVLLEEEANAQQ
CCHHHHHHHHHCCCCCCEECCCCEEEEEEECCHHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2687239; 9278503; 3049542 [H]