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The map label for this gene is yqhT [H]

Identifier: 227080303

GI number: 227080303

Start: 66289

End: 68082

Strand: Reverse

Name: yqhT [H]

Synonym: VCM66_0067

Alternate gene names: 227080303

Gene position: 68082-66289 (Counterclockwise)

Preceding gene: 227080304

Following gene: 227080295

Centisome position: 2.35

GC content: 50.56

Gene sequence:

>1794_bases
ATGTCAAACCTACACTCTCAACGCCTCGCGGATTTTCGCCACTGGCTACACACCCAGCAACTTGATGCCTTCATTGTTCC
TCATGAAGATGAATATCTTGGGGAATACGTTCCTGAGCATAATGAGCGCTTACACTGGTTAACTGGGTTTACAGGTTCCG
CGGGAGCCGCCATCGTTACCCTCTCCGGCGCAGCGATTTTTGTTGATGGCCGCTATACCGTTCAAGTCCGCAAACAAGTG
TCTAGTGAGCTATTCGAATATTGCCACTTGATCGAACAACCTTATTTAAACTGGCTCGTCACTCAACTGCCCGCAGGAGC
GAAAGTGGGTTACGATCCTCGCATGCACCGTGGTAGCTGGCTAACACAGGCACAAAAACAGCTCGCAGGAAAAATTAACT
TGTGTGCAGTCAGCAGTAACCCGATTGATTTACTCTGGCAGGATCGTCCAGTTCCCGCAGCCTCTGAAATGCGCTTAATA
CCTCTTGATCGTGTTGGACAAAGCAGCCTTGAAAAGCGTCAATCGATCGCCAGCACTCTGCGCGACAAAAACGCCGATTG
CGTCGTGTTGACCGAACTAGATTCTATCGCATGGCTACTCAATATCCGCGGTTTAGATGTATCTCGCTTACCCGTGTTGC
TTTCTCACGCCATTGTCCATAACGACAGCAGTGTGGATTTCTTTTTCGATCCGGCGCGCTTGGCAACCGATTTTGATGCC
CATGTAGCAGGTACGGTTCGCGTGCATCATCCGGATCAGCTTGAAGCTCAACTGCATCAACTCTCTGGTCGCCGCGTCAT
GCTCGATTCTGCGACCAGCAATGCATGGTTCACACTCACCTTACAAAATGCGGGCGCTGAACTGCTCAACGAAGCGGATC
CATGCCTCCTGCCGAAAGCGGCAAAAAATAACACGGAAATTGCAGGCATGCGTGCCTGTCATATTCGCGATGGTGCAGCT
ATGGTGCAATTTCTCGCTTGGCTGGACAATGAAGTGGCTAATGGTCGCCTGCATAATGAGGCCGAGCTGGCGGATCGACT
TGAAGCCTTCCGTCGCCAAGACCCAACCTTGGTTGACTTGAGTTTTGATACGATTTCAGCAGCTGGTACAAACGCCGCTA
TGTGCCACTACAACCACCAAAATCAGCCTGAGCCGGGTCAGCTTTCTATGGATAGCCTGTATTTAGTCGATTCTGGTGGC
CAGTACCTTGATGGAACCACAGACATTACTCGTACGGTGGCCATTGGCCAGGTCAGCGCAGAGATGAAGCAACAATTCAC
CTTAGTACTCAAAGGTCACATTGCCTTGGCTCGCGCTCGCTTCCCGAAAGGCACAACAGGTTCACAACTTGATGTTTTGG
CCAGACAGCACTTATGGGCACAAGGTTACGACTACGATCATGGTACTGGCCATGGTGTCGGCCATTTCTTAAGTGTACAT
GAAGGGCCACAGCGTATCGCGAAGGTTCACAATAGTGTGGCTTTGCGCCCCGGAATGGTGCTTTCCAATGAGCCGGGTTA
TTACCGTGCCGATGCGTTCGGCATTCGAATCGAGAACTTAGAGCTGGTCACCGAGTTTGCAACTCAGGGCGATTTCTCTG
TACTTGGTTTTGAATCATTGACTCGTTGCCCTATCGATAAACGTGCGATTGAGGTGAATTTGCTGACTAAGCCGGAACTC
CATTGGCTCAATCAGTATCATCAAAAAGTGTGGGATGAAGTGAGTCCGCTTATCAAAGAGGCTCACGTCCGTGAGTGGTT
GCAACAAGCCACCTCACCCTTGAGTCACGTATAA

Upstream 100 bases:

>100_bases
AAAAGAGTAGCTTATTCGCTCTCGTCCACTTGCTGTATGTGGTTCGTATAATCCATACACAAGAGATAACAAGGACTGTT
TAGAAAAAGGATCACTTCAG

Downstream 100 bases:

>100_bases
ACTGGCTGGTTATCCGCATAGAATAGAAAAGAAAACCGTCGTATGGCGGTTTTCTTTTTGTTGCTGCTATTTGTTTTGTC
GCTATCGTGGATGGGATTTA

Product: aminopeptidase P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MSNLHSQRLADFRHWLHTQQLDAFIVPHEDEYLGEYVPEHNERLHWLTGFTGSAGAAIVTLSGAAIFVDGRYTVQVRKQV
SSELFEYCHLIEQPYLNWLVTQLPAGAKVGYDPRMHRGSWLTQAQKQLAGKINLCAVSSNPIDLLWQDRPVPAASEMRLI
PLDRVGQSSLEKRQSIASTLRDKNADCVVLTELDSIAWLLNIRGLDVSRLPVLLSHAIVHNDSSVDFFFDPARLATDFDA
HVAGTVRVHHPDQLEAQLHQLSGRRVMLDSATSNAWFTLTLQNAGAELLNEADPCLLPKAAKNNTEIAGMRACHIRDGAA
MVQFLAWLDNEVANGRLHNEAELADRLEAFRRQDPTLVDLSFDTISAAGTNAAMCHYNHQNQPEPGQLSMDSLYLVDSGG
QYLDGTTDITRTVAIGQVSAEMKQQFTLVLKGHIALARARFPKGTTGSQLDVLARQHLWAQGYDYDHGTGHGVGHFLSVH
EGPQRIAKVHNSVALRPGMVLSNEPGYYRADAFGIRIENLELVTEFATQGDFSVLGFESLTRCPIDKRAIEVNLLTKPEL
HWLNQYHQKVWDEVSPLIKEAHVREWLQQATSPLSHV

Sequences:

>Translated_597_residues
MSNLHSQRLADFRHWLHTQQLDAFIVPHEDEYLGEYVPEHNERLHWLTGFTGSAGAAIVTLSGAAIFVDGRYTVQVRKQV
SSELFEYCHLIEQPYLNWLVTQLPAGAKVGYDPRMHRGSWLTQAQKQLAGKINLCAVSSNPIDLLWQDRPVPAASEMRLI
PLDRVGQSSLEKRQSIASTLRDKNADCVVLTELDSIAWLLNIRGLDVSRLPVLLSHAIVHNDSSVDFFFDPARLATDFDA
HVAGTVRVHHPDQLEAQLHQLSGRRVMLDSATSNAWFTLTLQNAGAELLNEADPCLLPKAAKNNTEIAGMRACHIRDGAA
MVQFLAWLDNEVANGRLHNEAELADRLEAFRRQDPTLVDLSFDTISAAGTNAAMCHYNHQNQPEPGQLSMDSLYLVDSGG
QYLDGTTDITRTVAIGQVSAEMKQQFTLVLKGHIALARARFPKGTTGSQLDVLARQHLWAQGYDYDHGTGHGVGHFLSVH
EGPQRIAKVHNSVALRPGMVLSNEPGYYRADAFGIRIENLELVTEFATQGDFSVLGFESLTRCPIDKRAIEVNLLTKPEL
HWLNQYHQKVWDEVSPLIKEAHVREWLQQATSPLSHV
>Mature_596_residues
SNLHSQRLADFRHWLHTQQLDAFIVPHEDEYLGEYVPEHNERLHWLTGFTGSAGAAIVTLSGAAIFVDGRYTVQVRKQVS
SELFEYCHLIEQPYLNWLVTQLPAGAKVGYDPRMHRGSWLTQAQKQLAGKINLCAVSSNPIDLLWQDRPVPAASEMRLIP
LDRVGQSSLEKRQSIASTLRDKNADCVVLTELDSIAWLLNIRGLDVSRLPVLLSHAIVHNDSSVDFFFDPARLATDFDAH
VAGTVRVHHPDQLEAQLHQLSGRRVMLDSATSNAWFTLTLQNAGAELLNEADPCLLPKAAKNNTEIAGMRACHIRDGAAM
VQFLAWLDNEVANGRLHNEAELADRLEAFRRQDPTLVDLSFDTISAAGTNAAMCHYNHQNQPEPGQLSMDSLYLVDSGGQ
YLDGTTDITRTVAIGQVSAEMKQQFTLVLKGHIALARARFPKGTTGSQLDVLARQHLWAQGYDYDHGTGHGVGHFLSVHE
GPQRIAKVHNSVALRPGMVLSNEPGYYRADAFGIRIENLELVTEFATQGDFSVLGFESLTRCPIDKRAIEVNLLTKPELH
WLNQYHQKVWDEVSPLIKEAHVREWLQQATSPLSHV

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=605, Percent_Identity=38.6776859504132, Blast_Score=378, Evalue=1e-104,
Organism=Homo sapiens, GI93141226, Length=604, Percent_Identity=35.0993377483444, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI264681565, Length=604, Percent_Identity=36.7549668874172, Blast_Score=348, Evalue=1e-95,
Organism=Escherichia coli, GI1788728, Length=193, Percent_Identity=33.6787564766839, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17509539, Length=623, Percent_Identity=35.4735152487961, Blast_Score=350, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI25149105, Length=598, Percent_Identity=31.9397993311037, Blast_Score=288, Evalue=8e-78,
Organism=Saccharomyces cerevisiae, GI6322999, Length=661, Percent_Identity=30.8623298033283, Blast_Score=293, Evalue=8e-80,
Organism=Drosophila melanogaster, GI17137632, Length=598, Percent_Identity=36.2876254180602, Blast_Score=354, Evalue=1e-97,
Organism=Drosophila melanogaster, GI161078230, Length=632, Percent_Identity=30.0632911392405, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI21357287, Length=632, Percent_Identity=30.0632911392405, Blast_Score=268, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 66611; Mature: 66480

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLHSQRLADFRHWLHTQQLDAFIVPHEDEYLGEYVPEHNERLHWLTGFTGSAGAAIVT
CCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEE
LSGAAIFVDGRYTVQVRKQVSSELFEYCHLIEQPYLNWLVTQLPAGAKVGYDPRMHRGSW
EECEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
LTQAQKQLAGKINLCAVSSNPIDLLWQDRPVPAASEMRLIPLDRVGQSSLEKRQSIASTL
HHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHH
RDKNADCVVLTELDSIAWLLNIRGLDVSRLPVLLSHAIVHNDSSVDFFFDPARLATDFDA
HCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCCC
HVAGTVRVHHPDQLEAQLHQLSGRRVMLDSATSNAWFTLTLQNAGAELLNEADPCLLPKA
EEEEEEEEECCHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCHHHHCCCCCCCCCCC
AKNNTEIAGMRACHIRDGAAMVQFLAWLDNEVANGRLHNEAELADRLEAFRRQDPTLVDL
CCCCCCEECEEEEEECCHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHCCCCCEEEE
SFDTISAAGTNAAMCHYNHQNQPEPGQLSMDSLYLVDSGGQYLDGTTDITRTVAIGQVSA
ECCCCCCCCCCCEEEEECCCCCCCCCCEECCEEEEEECCCCCCCCCCHHHHEEEHHHHHH
EMKQQFTLVLKGHIALARARFPKGTTGSQLDVLARQHLWAQGYDYDHGTGHGVGHFLSVH
HHHHHEEEEEECCCCEEHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHEECC
EGPQRIAKVHNSVALRPGMVLSNEPGYYRADAFGIRIENLELVTEFATQGDFSVLGFESL
CCHHHHHHHHHCEEECCCEEECCCCCEEEECEEEEEEECHHHHHHHHCCCCEEEECHHHH
TRCPIDKRAIEVNLLTKPELHWLNQYHQKVWDEVSPLIKEAHVREWLQQATSPLSHV
HCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SNLHSQRLADFRHWLHTQQLDAFIVPHEDEYLGEYVPEHNERLHWLTGFTGSAGAAIVT
CCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEEE
LSGAAIFVDGRYTVQVRKQVSSELFEYCHLIEQPYLNWLVTQLPAGAKVGYDPRMHRGSW
EECEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
LTQAQKQLAGKINLCAVSSNPIDLLWQDRPVPAASEMRLIPLDRVGQSSLEKRQSIASTL
HHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHH
RDKNADCVVLTELDSIAWLLNIRGLDVSRLPVLLSHAIVHNDSSVDFFFDPARLATDFDA
HCCCCCEEEEEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCCC
HVAGTVRVHHPDQLEAQLHQLSGRRVMLDSATSNAWFTLTLQNAGAELLNEADPCLLPKA
EEEEEEEEECCHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCHHHHCCCCCCCCCCC
AKNNTEIAGMRACHIRDGAAMVQFLAWLDNEVANGRLHNEAELADRLEAFRRQDPTLVDL
CCCCCCEECEEEEEECCHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHCCCCCEEEE
SFDTISAAGTNAAMCHYNHQNQPEPGQLSMDSLYLVDSGGQYLDGTTDITRTVAIGQVSA
ECCCCCCCCCCCEEEEECCCCCCCCCCEECCEEEEEECCCCCCCCCCHHHHEEEHHHHHH
EMKQQFTLVLKGHIALARARFPKGTTGSQLDVLARQHLWAQGYDYDHGTGHGVGHFLSVH
HHHHHEEEEEECCCCEEHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHEECC
EGPQRIAKVHNSVALRPGMVLSNEPGYYRADAFGIRIENLELVTEFATQGDFSVLGFESL
CCHHHHHHHHHCEEECCCEEECCCCCEEEECEEEEEEECHHHHHHHHCCCCEEEECHHHH
TRCPIDKRAIEVNLLTKPELHWLNQYHQKVWDEVSPLIKEAHVREWLQQATSPLSHV
HCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]