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The map label for this gene is fruB

Identifier: 226224881

GI number: 226224881

Start: 2369399

End: 2370322

Strand: Reverse

Name: fruB

Synonym: Lm4b_02300

Alternate gene names: 226224881

Gene position: 2370322-2369399 (Counterclockwise)

Preceding gene: 226224882

Following gene: 226224880

Centisome position: 81.38

GC content: 36.8

Gene sequence:

>924_bases
ATGATTTATACAATTACTTTAAACCCATCAATTGATTATATTGTACAAATCGGCCAATTAAATCTTGGCGGTCTTAATCG
CATGAAGCAAGATTATAAACTACCTGGTGGCAAAGGAATTAATGTCAGCAGAGTTTTAAATCAATTAAATGTACCAAGTC
TTGCTACAGGATTTTTAGGTGGATTTACAGGCAATTTTATCAAAGACTGGCTACAAAACGAAGGTGTGAAAACTGGCTTT
GTAACAGTGAAAGATGACACTCGTATTAATATCAAACTAAAACACGGAGAAGAAACAGAAATTAATGGTCTAGGGCCAGC
TATTTCTGAAAAAGAAATCAATGGATTTTTGAAAGTGATGGATAAAGTAACTGCTAACGATATTGTTATTTTATCTGGTA
GTGTGCCTCCTTCACTTGGAAATGATTTTTACAATAAAATAATTCAAATTTGCAAAGAAAAAAAAGCTGAATTTATGATT
GATACAACTGGACAAGAACTGCTAGATGCATTACCAAACCACCCGATTCTAATTAAACCAAATCACCACGAACTAGCAGA
CCTATTTGGCGTGAAACTTGGTAGCGTAGAAGAACTTATCCCATACGGGAAAAAATGTTTAGAATTAGGCGCGCAACATG
TAATCGTGTCCATGGCTGGTGACGGAGCGCTTCTATTTACAGGAGAAGATGTTTACTTCGCCGATGCATTAAAAGGGGAA
CTGAAAAATTCCGTAGGTGCTGGAGACTCAATGATTGCAGGCTTTGTTGGGACTTTTGATAAAACGAGAGATCCCGTTAA
AGCTTTTGCTGCAGGAGTTGCAACAGGTGGAGCTACTGCATTTTCAACAGATTTAGCCCAAAAAGAACTAATAGATGAAC
TATTACCGCAAGTGAAGATAACCAAAATAACAGGGAGGAACTAA

Upstream 100 bases:

>100_bases
AAATGTTTTCAATAGAAGAAGCAACTATTGTGACAGATTACATTCCTTCTGCAGTAAAAGAATCCTTTATCCAAAAAACT
AAAATAATCGAGGTAGAAAA

Downstream 100 bases:

>100_bases
AATGAGAATCACTGATTTATTAAGCAAAGATGTTATGATTATGTCATTACAGGCAACGACAAAAGAAGCTGCCATCGATG
AAATGATTGCTTCGTTAAAG

Product: fructose-1-phosphate kinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MIYTITLNPSIDYIVQIGQLNLGGLNRMKQDYKLPGGKGINVSRVLNQLNVPSLATGFLGGFTGNFIKDWLQNEGVKTGF
VTVKDDTRINIKLKHGEETEINGLGPAISEKEINGFLKVMDKVTANDIVILSGSVPPSLGNDFYNKIIQICKEKKAEFMI
DTTGQELLDALPNHPILIKPNHHELADLFGVKLGSVEELIPYGKKCLELGAQHVIVSMAGDGALLFTGEDVYFADALKGE
LKNSVGAGDSMIAGFVGTFDKTRDPVKAFAAGVATGGATAFSTDLAQKELIDELLPQVKITKITGRN

Sequences:

>Translated_307_residues
MIYTITLNPSIDYIVQIGQLNLGGLNRMKQDYKLPGGKGINVSRVLNQLNVPSLATGFLGGFTGNFIKDWLQNEGVKTGF
VTVKDDTRINIKLKHGEETEINGLGPAISEKEINGFLKVMDKVTANDIVILSGSVPPSLGNDFYNKIIQICKEKKAEFMI
DTTGQELLDALPNHPILIKPNHHELADLFGVKLGSVEELIPYGKKCLELGAQHVIVSMAGDGALLFTGEDVYFADALKGE
LKNSVGAGDSMIAGFVGTFDKTRDPVKAFAAGVATGGATAFSTDLAQKELIDELLPQVKITKITGRN
>Mature_307_residues
MIYTITLNPSIDYIVQIGQLNLGGLNRMKQDYKLPGGKGINVSRVLNQLNVPSLATGFLGGFTGNFIKDWLQNEGVKTGF
VTVKDDTRINIKLKHGEETEINGLGPAISEKEINGFLKVMDKVTANDIVILSGSVPPSLGNDFYNKIIQICKEKKAEFMI
DTTGQELLDALPNHPILIKPNHHELADLFGVKLGSVEELIPYGKKCLELGAQHVIVSMAGDGALLFTGEDVYFADALKGE
LKNSVGAGDSMIAGFVGTFDKTRDPVKAFAAGVATGGATAFSTDLAQKELIDELLPQVKITKITGRN

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=261, Percent_Identity=30.2681992337165, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1788017, Length=285, Percent_Identity=28.7719298245614, Blast_Score=104, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 33062; Mature: 33062

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTITLNPSIDYIVQIGQLNLGGLNRMKQDYKLPGGKGINVSRVLNQLNVPSLATGFLG
CEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHH
GFTGNFIKDWLQNEGVKTGFVTVKDDTRINIKLKHGEETEINGLGPAISEKEINGFLKVM
CCCHHHHHHHHHCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
DKVTANDIVILSGSVPPSLGNDFYNKIIQICKEKKAEFMIDTTGQELLDALPNHPILIKP
HHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCEEECC
NHHELADLFGVKLGSVEELIPYGKKCLELGAQHVIVSMAGDGALLFTGEDVYFADALKGE
CCHHHHHHHHCCCCCHHHHHHCCHHHHHCCCCEEEEEECCCCEEEEECCCEEEHHHHHHH
LKNSVGAGDSMIAGFVGTFDKTRDPVKAFAAGVATGGATAFSTDLAQKELIDELLPQVKI
HHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEE
TKITGRN
EEECCCC
>Mature Secondary Structure
MIYTITLNPSIDYIVQIGQLNLGGLNRMKQDYKLPGGKGINVSRVLNQLNVPSLATGFLG
CEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHH
GFTGNFIKDWLQNEGVKTGFVTVKDDTRINIKLKHGEETEINGLGPAISEKEINGFLKVM
CCCHHHHHHHHHCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
DKVTANDIVILSGSVPPSLGNDFYNKIIQICKEKKAEFMIDTTGQELLDALPNHPILIKP
HHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCEEECC
NHHELADLFGVKLGSVEELIPYGKKCLELGAQHVIVSMAGDGALLFTGEDVYFADALKGE
CCHHHHHHHHCCCCCHHHHHHCCHHHHHCCCCEEEEEECCCCEEEEECCCEEEHHHHHHH
LKNSVGAGDSMIAGFVGTFDKTRDPVKAFAAGVATGGATAFSTDLAQKELIDELLPQVKI
HHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEE
TKITGRN
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]