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The map label for this gene is fruR [H]

Identifier: 226224882

GI number: 226224882

Start: 2370319

End: 2371071

Strand: Reverse

Name: fruR [H]

Synonym: Lm4b_02301

Alternate gene names: 226224882

Gene position: 2371071-2370319 (Counterclockwise)

Preceding gene: 226224884

Following gene: 226224881

Centisome position: 81.4

GC content: 35.06

Gene sequence:

>753_bases
ATGTTAAATGCAGAGCGTAAACAACTTATTATGGAGAGTATTGAGAAACTTGGTGTGATTAAATTACAAGAATTAGTTGA
AGGTCTTGCTACCTCAGAGTCAACCATTCGCCGTGATTTAATCGAGTTAGAAGAACAAGGATTAATTCAGCGCGTACACG
GCGGGGCGAAACTTGTAAAACTTCATAATCAAGAACCAAGTATGAATGAAAAATCATTCAAAAACATTCAAAGTAAAAAA
GTAATTGCTGCATATTGTGCAAGCCTAGTGGAAGAAAATGATTGTATCTATTTAGATGCAGGATCCACAACATTAGAATT
AATTACTCACCTAGCAAATCGAAATATCACAGTAGTGACAAATGGATTAACCCATATTGAAGAGCTTGTTCGTCAAAATA
TAGATGCTTATCTTTTAGGCGGCAAAATGAAAGTGCATACAAAAGCAATTATTGGTGCAGTTGCCTTAGATAACATTCAA
AACTATCATTTTGATAAAGCTTTCATTGGTACCAACGCGATGCATCCGGAGCATGGCTACACAACACCTGATATGGAAGA
GGCATTTGTAAAACGTGCTGCAAAAGAACGTGCTGATCGCGTTTTTGTTGTAGCAGACCATACAAAATTCAATGAAGTGA
ATTTTTCAAAAATGTTTTCAATAGAAGAAGCAACTATTGTGACAGATTACATTCCTTCTGCAGTAAAAGAATCCTTTATC
CAAAAAACTAAAATAATCGAGGTAGAAAAATGA

Upstream 100 bases:

>100_bases
ATAATATGAATGAATTTGAAAATGTGTGATTGTTTTTGAATGAAAACGGTTGATTTTGAAAGAAAAAGATGGTAAACTGA
CTTTGGATGGAGGAGTAATA

Downstream 100 bases:

>100_bases
TTTATACAATTACTTTAAACCCATCAATTGATTATATTGTACAAATCGGCCAATTAAATCTTGGCGGTCTTAATCGCATG
AAGCAAGATTATAAACTACC

Product: regulatory protein DeoR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLNAERKQLIMESIEKLGVIKLQELVEGLATSESTIRRDLIELEEQGLIQRVHGGAKLVKLHNQEPSMNEKSFKNIQSKK
VIAAYCASLVEENDCIYLDAGSTTLELITHLANRNITVVTNGLTHIEELVRQNIDAYLLGGKMKVHTKAIIGAVALDNIQ
NYHFDKAFIGTNAMHPEHGYTTPDMEEAFVKRAAKERADRVFVVADHTKFNEVNFSKMFSIEEATIVTDYIPSAVKESFI
QKTKIIEVEK

Sequences:

>Translated_250_residues
MLNAERKQLIMESIEKLGVIKLQELVEGLATSESTIRRDLIELEEQGLIQRVHGGAKLVKLHNQEPSMNEKSFKNIQSKK
VIAAYCASLVEENDCIYLDAGSTTLELITHLANRNITVVTNGLTHIEELVRQNIDAYLLGGKMKVHTKAIIGAVALDNIQ
NYHFDKAFIGTNAMHPEHGYTTPDMEEAFVKRAAKERADRVFVVADHTKFNEVNFSKMFSIEEATIVTDYIPSAVKESFI
QKTKIIEVEK
>Mature_250_residues
MLNAERKQLIMESIEKLGVIKLQELVEGLATSESTIRRDLIELEEQGLIQRVHGGAKLVKLHNQEPSMNEKSFKNIQSKK
VIAAYCASLVEENDCIYLDAGSTTLELITHLANRNITVVTNGLTHIEELVRQNIDAYLLGGKMKVHTKAIIGAVALDNIQ
NYHFDKAFIGTNAMHPEHGYTTPDMEEAFVKRAAKERADRVFVVADHTKFNEVNFSKMFSIEEATIVTDYIPSAVKESFI
QKTKIIEVEK

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI226510968, Length=247, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789519, Length=237, Percent_Identity=31.2236286919831, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789059, Length=229, Percent_Identity=31.8777292576419, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789829, Length=239, Percent_Identity=32.2175732217573, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787540, Length=228, Percent_Identity=29.8245614035088, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790753, Length=231, Percent_Identity=29.4372294372294, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI87082344, Length=248, Percent_Identity=27.8225806451613, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788069, Length=217, Percent_Identity=26.2672811059908, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790635, Length=215, Percent_Identity=25.5813953488372, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=27.1551724137931, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787063, Length=251, Percent_Identity=26.2948207171315, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28128; Mature: 28128

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAERKQLIMESIEKLGVIKLQELVEGLATSESTIRRDLIELEEQGLIQRVHGGAKLVK
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LHNQEPSMNEKSFKNIQSKKVIAAYCASLVEENDCIYLDAGSTTLELITHLANRNITVVT
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEEEE
NGLTHIEELVRQNIDAYLLGGKMKVHTKAIIGAVALDNIQNYHFDKAFIGTNAMHPEHGY
CCHHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCC
TTPDMEEAFVKRAAKERADRVFVVADHTKFNEVNFSKMFSIEEATIVTDYIPSAVKESFI
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHH
QKTKIIEVEK
HHHHEEEECC
>Mature Secondary Structure
MLNAERKQLIMESIEKLGVIKLQELVEGLATSESTIRRDLIELEEQGLIQRVHGGAKLVK
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LHNQEPSMNEKSFKNIQSKKVIAAYCASLVEENDCIYLDAGSTTLELITHLANRNITVVT
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEEEE
NGLTHIEELVRQNIDAYLLGGKMKVHTKAIIGAVALDNIQNYHFDKAFIGTNAMHPEHGY
CCHHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCC
TTPDMEEAFVKRAAKERADRVFVVADHTKFNEVNFSKMFSIEEATIVTDYIPSAVKESFI
CCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHH
QKTKIIEVEK
HHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]