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The map label for this gene is yybE [H]

Identifier: 226224841

GI number: 226224841

Start: 2329319

End: 2330197

Strand: Reverse

Name: yybE [H]

Synonym: Lm4b_02260

Alternate gene names: 226224841

Gene position: 2330197-2329319 (Counterclockwise)

Preceding gene: 226224847

Following gene: 226224837

Centisome position: 80.0

GC content: 39.14

Gene sequence:

>879_bases
ATGAATTTACACCATTTACGATACTTCGTCACACTGGCGCACATGGAGCATTACACAAAAGCAGCTGAAAAATTGCTGAT
TACACAGCCTAGTTTAAGTCACGCAATTTCCTCCTTAGAGCAAGAATTAGGTATCCCTTTATTTGAAAAAGAAGGGCGGA
ATATAGGGTTAAGTAAAGCTGGCAAAGTATTTCTTGATTATGTGGAAGAGTCCTTAGATATGATTGATGCGGGTGTCGCG
ACGACTAAAAAAGCGGCGAATGGGGAAGGGCAGATTGACTTGGCATTCTTGCAAACACTTGGCACGTCTCTAATACCAAA
GCTTGTTCAAGAATTTCTCCAAACCGAACCAGAAAAACAAATCGATTTTATTTTCCATACAGGTGTTTCGATTGATATCA
TTCAAGGCCTAAAAGAAAAGAAATTTGATATTGGTATTTGTTCTAAACTTGAAAATGAAAGAAATATTCACTTTACGCCA
ATTGCCAAACAAGAATTAGTGCTCATCGTCCCCAAAAGCCATCCTCTTGCTGAGAAAGACTGGATTGATTTAATCGAAAC
GGTAGATTATCCGCATATCGCATTCTCGAAAAAAAGTGGTTTGCGTCCAATTATCGATGATTTGTTCAGAAAAATTGGTG
CCGATTATCAAATTGCATATGAAATTGAAGTGGATCAAGTCATTGCCGGAATGGTCGCGCAAAACTTTGGGATTGCTGTA
GTTCCGAACATGCCGATTTTAAATTATGTGGATGTCAAAGTCTTACCAATTAGAAGCCCAAACTGGGAGAGATTCTTTTA
TCTCGCAGTCGCGAAAAACCAAACGCTAACGCCCGCAGCTGAGAAGTTCAAGCAATTTATGTTAGCGCATCGTATATAA

Upstream 100 bases:

>100_bases
CAGTCTAATTGTATTATGACTATTCCATAAAAACAAATTGGTATTGTTCTATTAATTGATAGATAAATTGCATAGATAAC
TTTTTAGTTAGGAGAGAAGC

Downstream 100 bases:

>100_bases
AAAAAGTAGCTATCCTACGAGAGGGATAGCTACTTTTTGATTAGTCATTCGTTTTTTTGATGATTTCGATATATTCAATA
TGATGAGGTTCGCCTTGTTT

Product: transcriptional regulator (LysR family)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MNLHHLRYFVTLAHMEHYTKAAEKLLITQPSLSHAISSLEQELGIPLFEKEGRNIGLSKAGKVFLDYVEESLDMIDAGVA
TTKKAANGEGQIDLAFLQTLGTSLIPKLVQEFLQTEPEKQIDFIFHTGVSIDIIQGLKEKKFDIGICSKLENERNIHFTP
IAKQELVLIVPKSHPLAEKDWIDLIETVDYPHIAFSKKSGLRPIIDDLFRKIGADYQIAYEIEVDQVIAGMVAQNFGIAV
VPNMPILNYVDVKVLPIRSPNWERFFYLAVAKNQTLTPAAEKFKQFMLAHRI

Sequences:

>Translated_292_residues
MNLHHLRYFVTLAHMEHYTKAAEKLLITQPSLSHAISSLEQELGIPLFEKEGRNIGLSKAGKVFLDYVEESLDMIDAGVA
TTKKAANGEGQIDLAFLQTLGTSLIPKLVQEFLQTEPEKQIDFIFHTGVSIDIIQGLKEKKFDIGICSKLENERNIHFTP
IAKQELVLIVPKSHPLAEKDWIDLIETVDYPHIAFSKKSGLRPIIDDLFRKIGADYQIAYEIEVDQVIAGMVAQNFGIAV
VPNMPILNYVDVKVLPIRSPNWERFFYLAVAKNQTLTPAAEKFKQFMLAHRI
>Mature_292_residues
MNLHHLRYFVTLAHMEHYTKAAEKLLITQPSLSHAISSLEQELGIPLFEKEGRNIGLSKAGKVFLDYVEESLDMIDAGVA
TTKKAANGEGQIDLAFLQTLGTSLIPKLVQEFLQTEPEKQIDFIFHTGVSIDIIQGLKEKKFDIGICSKLENERNIHFTP
IAKQELVLIVPKSHPLAEKDWIDLIETVDYPHIAFSKKSGLRPIIDDLFRKIGADYQIAYEIEVDQVIAGMVAQNFGIAV
VPNMPILNYVDVKVLPIRSPNWERFFYLAVAKNQTLTPAAEKFKQFMLAHRI

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=28.169014084507, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=27.7027027027027, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=26.3157894736842, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788887, Length=289, Percent_Identity=26.643598615917, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788748, Length=285, Percent_Identity=25.2631578947368, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790399, Length=297, Percent_Identity=23.5690235690236, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787530, Length=255, Percent_Identity=25.0980392156863, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789204, Length=252, Percent_Identity=23.8095238095238, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787806, Length=293, Percent_Identity=25.2559726962457, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082132, Length=245, Percent_Identity=24.4897959183673, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788296, Length=249, Percent_Identity=27.3092369477912, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI2367136, Length=245, Percent_Identity=24.4897959183673, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87081904, Length=217, Percent_Identity=27.1889400921659, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=21.7993079584775, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=289, Percent_Identity=22.8373702422145, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790208, Length=303, Percent_Identity=23.4323432343234, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=214, Percent_Identity=23.3644859813084, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=299, Percent_Identity=23.0769230769231, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32996; Mature: 32996

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHHLRYFVTLAHMEHYTKAAEKLLITQPSLSHAISSLEQELGIPLFEKEGRNIGLSKA
CCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHH
GKVFLDYVEESLDMIDAGVATTKKAANGEGQIDLAFLQTLGTSLIPKLVQEFLQTEPEKQ
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IDFIFHTGVSIDIIQGLKEKKFDIGICSKLENERNIHFTPIAKQELVLIVPKSHPLAEKD
EEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCHHH
WIDLIETVDYPHIAFSKKSGLRPIIDDLFRKIGADYQIAYEIEVDQVIAGMVAQNFGIAV
HHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHCCCEEE
VPNMPILNYVDVKVLPIRSPNWERFFYLAVAKNQTLTPAAEKFKQFMLAHRI
ECCCCCEEEECEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLHHLRYFVTLAHMEHYTKAAEKLLITQPSLSHAISSLEQELGIPLFEKEGRNIGLSKA
CCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHH
GKVFLDYVEESLDMIDAGVATTKKAANGEGQIDLAFLQTLGTSLIPKLVQEFLQTEPEKQ
HHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IDFIFHTGVSIDIIQGLKEKKFDIGICSKLENERNIHFTPIAKQELVLIVPKSHPLAEKD
EEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCCEEEEEECCCCCCHHH
WIDLIETVDYPHIAFSKKSGLRPIIDDLFRKIGADYQIAYEIEVDQVIAGMVAQNFGIAV
HHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHCCCEEE
VPNMPILNYVDVKVLPIRSPNWERFFYLAVAKNQTLTPAAEKFKQFMLAHRI
ECCCCCEEEECEEEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]