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The map label for this gene is malE [C]

Identifier: 226224333

GI number: 226224333

Start: 1782110

End: 1783354

Strand: Direct

Name: malE [C]

Synonym: Lm4b_01744

Alternate gene names: 226224333

Gene position: 1782110-1783354 (Clockwise)

Preceding gene: 226224319

Following gene: 226224334

Centisome position: 61.18

GC content: 38.8

Gene sequence:

>1245_bases
ATGAAGAAAAAGATGTTTGTCGTTTTAGCTTTAGTGTTGTCGCTTAGTTTAGTGTTAATGGCGTGTGGTGGGTCAAAGGA
TGATGCAAATTCCGGCGATTCTAAAGTATTAAATGTTTGGGCAATGGGTGATGAAGCCAAGTCACTAAAAGAACTCGCAC
AAAAATTCACGAAAGATACTGGCATTGAAGTTAAAGTTCAAGTTATTCCTTGGGCAAATGCACATGATAAATTACTTACA
GCCGTTGCTTCTAAATCTGGCCCCGATGTAGTCCAAATGGGAACTACTTGGATGCCTGAATTTGTCGAAGCTGGCGCACT
ACTTGATATTACAAAAGATGTCGAAAAAAGTAAAAATATGAATTCTGATCTATTTTTCCCAGGTTCAGTAAAAACTACTC
AATTTGACGGGAAAACTTACGGTGTTCCGTGGTATGCAGAAACTCGCGTATTATTCTACCGTACCGATTTACTGAAAAAA
GTTGGTTATAATGAAGCTCCAAAAACATGGGATGAACTATCCGACGCTGCACTTAAACTTTCTAAACGTGGCAAAGATAT
GTACGGCTTTGCCATTGATCCAAACGAACAAACGACTGGTTTCATTTTCGGACGTCAAAACGGCTCCCCTCTTTTCGATA
AAGATGGTCAACCAGTATTCAATAAAAAACCTTTCGTAGACACTGTTAGTTATTTAGATAGTTTCATTAAAAATGGTTCC
GCTCCAGATACTGATCTTGGTTTAGATGCTTCTCAAAGCTTCGGCGGCGACGGTATTGTGCCAATGTTCATGAGTGGTCC
TTGGATGGTTAATACACTGAAAGACACTGCCCCTGACATTGACGGAAAATGGGCTACTGCAGTATTACCTAAAAAAGAAA
ATAACGAATCAAGCCTTGGTGGCGCTAACCTTTCCATTTTCAAATATAGTGATAAGAAAGATGATGCTCTAAAATTCATG
GACTACATGAGTCAACCTGATGTGCAATTATCTTGGTTAAAAGATACAAACTCCATGCCAGCTCGTATGGATGCTTGGGA
AGATGATATGCTGAAAAATGACCCTTACTACAAAGTATTCGGCGAACAAATGAAAACAGCTGAACCAATGCCACTTATCC
CACAATTTGAGGAAATCGCTCAATTATATGGAAAATCTTGGGAACAAATTTATCGTGGTGGTGCAGATGTACAAACACAA
ATGGATACTTTCAACGATCAAGTAGAAGCACTTCTTAAAAAATAA

Upstream 100 bases:

>100_bases
ATCCCGTACGGCGCACTAGTTCCGTGCAACAGTTTTTATTCTTTAACAGCTTTTAGTTAATCAAGTTGCTTTGAAAAAAA
CAAAAAATGGAGGAAAAATC

Downstream 100 bases:

>100_bases
CGAATAAAAAGGGCAAATGATTTATTCTGCCATTTGCCCTTTTAGAATGGACTGGATGTTATGAAACAATTTTTAAATAA
AAATACACCCTATTTGTTTA

Product: sugar ABC transporter binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKKKMFVVLALVLSLSLVLMACGGSKDDANSGDSKVLNVWAMGDEAKSLKELAQKFTKDTGIEVKVQVIPWANAHDKLLT
AVASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNMNSDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKK
VGYNEAPKTWDELSDAALKLSKRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGQPVFNKKPFVDTVSYLDSFIKNGS
APDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLGGANLSIFKYSDKKDDALKFM
DYMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVFGEQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGADVQTQ
MDTFNDQVEALLKK

Sequences:

>Translated_414_residues
MKKKMFVVLALVLSLSLVLMACGGSKDDANSGDSKVLNVWAMGDEAKSLKELAQKFTKDTGIEVKVQVIPWANAHDKLLT
AVASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNMNSDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKK
VGYNEAPKTWDELSDAALKLSKRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGQPVFNKKPFVDTVSYLDSFIKNGS
APDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLGGANLSIFKYSDKKDDALKFM
DYMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVFGEQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGADVQTQ
MDTFNDQVEALLKK
>Mature_414_residues
MKKKMFVVLALVLSLSLVLMACGGSKDDANSGDSKVLNVWAMGDEAKSLKELAQKFTKDTGIEVKVQVIPWANAHDKLLT
AVASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNMNSDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKK
VGYNEAPKTWDELSDAALKLSKRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGQPVFNKKPFVDTVSYLDSFIKNGS
APDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLGGANLSIFKYSDKKDDALKFM
DYMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVFGEQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGADVQTQ
MDTFNDQVEALLKK

Specific function: Probably part of an ABC transporter complex [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790466, Length=379, Percent_Identity=25.5936675461741, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787569, Length=409, Percent_Identity=22.2493887530562, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059
- InterPro:   IPR006061 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 46069; Mature: 46069

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKMFVVLALVLSLSLVLMACGGSKDDANSGDSKVLNVWAMGDEAKSLKELAQKFTKDT
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCC
GIEVKVQVIPWANAHDKLLTAVASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNM
CCEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHCCCEEEHHHHHHHHCCC
NSDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKKVGYNEAPKTWDELSDAALKL
CCCEEECCCCEEEEECCEEECCCCEECCEEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHH
SKRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGQPVFNKKPFVDTVSYLDSFIKNGS
HHCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
APDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLG
CCCCCCCCCCCCCCCCCCCEEHEECCCEEEEEHHHCCCCCCCCEEEEECCCCCCCCCCCC
GANLSIFKYSDKKDDALKFMDYMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVF
CCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCHHHHH
GEQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGADVQTQMDTFNDQVEALLKK
HHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKKMFVVLALVLSLSLVLMACGGSKDDANSGDSKVLNVWAMGDEAKSLKELAQKFTKDT
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCC
GIEVKVQVIPWANAHDKLLTAVASKSGPDVVQMGTTWMPEFVEAGALLDITKDVEKSKNM
CCEEEEEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHCCCEEEHHHHHHHHCCC
NSDLFFPGSVKTTQFDGKTYGVPWYAETRVLFYRTDLLKKVGYNEAPKTWDELSDAALKL
CCCEEECCCCEEEEECCEEECCCCEECCEEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHH
SKRGKDMYGFAIDPNEQTTGFIFGRQNGSPLFDKDGQPVFNKKPFVDTVSYLDSFIKNGS
HHCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
APDTDLGLDASQSFGGDGIVPMFMSGPWMVNTLKDTAPDIDGKWATAVLPKKENNESSLG
CCCCCCCCCCCCCCCCCCCEEHEECCCEEEEEHHHCCCCCCCCEEEEECCCCCCCCCCCC
GANLSIFKYSDKKDDALKFMDYMSQPDVQLSWLKDTNSMPARMDAWEDDMLKNDPYYKVF
CCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHCCCCHHHHH
GEQMKTAEPMPLIPQFEEIAQLYGKSWEQIYRGGADVQTQMDTFNDQVEALLKK
HHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA