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The map label for this gene is murQ

Identifier: 226224261

GI number: 226224261

Start: 1693272

End: 1694162

Strand: Reverse

Name: murQ

Synonym: Lm4b_01671

Alternate gene names: 226224261

Gene position: 1694162-1693272 (Counterclockwise)

Preceding gene: 226224262

Following gene: 226224260

Centisome position: 58.16

GC content: 37.04

Gene sequence:

>891_bases
ATGTTAGAGAATTTAGCAACAGAAGAACGAAATGAAAAAACGATTGACTTAGACACACTTTCTCCAAAAGAAATTTTAGC
AGTAATGAATGAAGAAGATTTAACAGTTCCAATAGCTATAAAAAAGGTCTTACCTCAAATCGAGTTAATTGTAAGCGGTG
TCATCTCGTGCTTTCAAAAAGGTGGCCGTTTGATTTATCTTGGTGCCGGAACAAGTGGAAGATTAGGAGTACTTGATGCA
GCTGAATGTGTTCCAACTTTCGGGGTCTCAAAGGAGCAGGTCATTGGCTTAATCGCAGGTGGTGAAAAAGCTTTTGTAGC
TGCAATAGAAGGTGCGGAAGATTCAAAAATACTTGGCGAAAACGACTTAAAGCAAATTAAGTTAACTGCAAACGATTTTG
TTATTGGTATTGCTGCAAGTGGTAGAACGCCTTATGTAATTGGCGCACTTGATTACGCCAAATCTGTCGGGGCTAAAACC
GGAGCAATTTCTTGTAATGCTAATGCAAAAATTTCAGCGCACGCCGATATAGCCGTAGAAGTTGTGACTGGAGCGGAAAT
TTTAACAGGTTCTACTAGGTTAAAAGCAGGAACAGCTCAGAAACTAGTATTAAATATGATTTCAACAGCTTCAATGGTTG
GAATTGGAAAAGTGTATAAAAATTTGATGGTGGACGTTTTACCAACAAATAAAAAATTAGAAGAGCGCTCTAAACGAATT
ATTATGGAAGCTACAGAGGCTGATTACGAAACAGCAAATAAATTTTATGAAGCAGCTGAAAAACATGTCAAAGTTGCCAT
TGTCATGATCTTAACCAATTCAACCAAAGAAATAGCGTTAGAAAAATTAAGTGAAGCAAAAGGGTTTGTTCGAAACACCA
TTCAAAAATAA

Upstream 100 bases:

>100_bases
ATTTTTTTACTAGCAATTATAAATAAAAATTTTAATATTAAAATTATATATTGAAATTTTATTTCATTTATATTATACTG
TGTTGGAAGGAGTGGTTAAA

Downstream 100 bases:

>100_bases
GGAGCTGGAATAATGACAAAAGAAGCAGAAATTGGAAAACAAATATTTATTCATGTCGGTGGAATGGAAAACGTTTCAAG
AATTGCACATTGTATGACAC

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MLENLATEERNEKTIDLDTLSPKEILAVMNEEDLTVPIAIKKVLPQIELIVSGVISCFQKGGRLIYLGAGTSGRLGVLDA
AECVPTFGVSKEQVIGLIAGGEKAFVAAIEGAEDSKILGENDLKQIKLTANDFVIGIAASGRTPYVIGALDYAKSVGAKT
GAISCNANAKISAHADIAVEVVTGAEILTGSTRLKAGTAQKLVLNMISTASMVGIGKVYKNLMVDVLPTNKKLEERSKRI
IMEATEADYETANKFYEAAEKHVKVAIVMILTNSTKEIALEKLSEAKGFVRNTIQK

Sequences:

>Translated_296_residues
MLENLATEERNEKTIDLDTLSPKEILAVMNEEDLTVPIAIKKVLPQIELIVSGVISCFQKGGRLIYLGAGTSGRLGVLDA
AECVPTFGVSKEQVIGLIAGGEKAFVAAIEGAEDSKILGENDLKQIKLTANDFVIGIAASGRTPYVIGALDYAKSVGAKT
GAISCNANAKISAHADIAVEVVTGAEILTGSTRLKAGTAQKLVLNMISTASMVGIGKVYKNLMVDVLPTNKKLEERSKRI
IMEATEADYETANKFYEAAEKHVKVAIVMILTNSTKEIALEKLSEAKGFVRNTIQK
>Mature_296_residues
MLENLATEERNEKTIDLDTLSPKEILAVMNEEDLTVPIAIKKVLPQIELIVSGVISCFQKGGRLIYLGAGTSGRLGVLDA
AECVPTFGVSKEQVIGLIAGGEKAFVAAIEGAEDSKILGENDLKQIKLTANDFVIGIAASGRTPYVIGALDYAKSVGAKT
GAISCNANAKISAHADIAVEVVTGAEILTGSTRLKAGTAQKLVLNMISTASMVGIGKVYKNLMVDVLPTNKKLEERSKRI
IMEATEADYETANKFYEAAEKHVKVAIVMILTNSTKEIALEKLSEAKGFVRNTIQK

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=295, Percent_Identity=50.8474576271186, Blast_Score=292, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_LISMC (C1KVV7)

Other databases:

- EMBL:   FM242711
- RefSeq:   YP_002758368.1
- ProteinModelPortal:   C1KVV7
- SMR:   C1KVV7
- GeneID:   7702697
- GenomeReviews:   FM242711_GR
- KEGG:   lmc:Lm4b_01671
- OMA:   SMIGVGK
- ProtClustDB:   PRK05441
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 31525; Mature: 31525

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 82-82 ACT_SITE 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENLATEERNEKTIDLDTLSPKEILAVMNEEDLTVPIAIKKVLPQIELIVSGVISCFQK
CCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHC
GGRLIYLGAGTSGRLGVLDAAECVPTFGVSKEQVIGLIAGGEKAFVAAIEGAEDSKILGE
CCEEEEEECCCCCCEECCCHHHHCCCCCCCHHHEEEEEECCCEEEEEEEECCCCCCCCCC
NDLKQIKLTANDFVIGIAASGRTPYVIGALDYAKSVGAKTGAISCNANAKISAHADIAVE
CCCEEEEEEECCEEEEEEECCCCCEEEEEHHHHHHCCCCCCEEEECCCCEEEECCCEEEE
VVTGAEILTGSTRLKAGTAQKLVLNMISTASMVGIGKVYKNLMVDVLPTNKKLEERSKRI
EEECCEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHEE
IMEATEADYETANKFYEAAEKHVKVAIVMILTNSTKEIALEKLSEAKGFVRNTIQK
EEEECCCCHHHHHHHHHHHHCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLENLATEERNEKTIDLDTLSPKEILAVMNEEDLTVPIAIKKVLPQIELIVSGVISCFQK
CCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHC
GGRLIYLGAGTSGRLGVLDAAECVPTFGVSKEQVIGLIAGGEKAFVAAIEGAEDSKILGE
CCEEEEEECCCCCCEECCCHHHHCCCCCCCHHHEEEEEECCCEEEEEEEECCCCCCCCCC
NDLKQIKLTANDFVIGIAASGRTPYVIGALDYAKSVGAKTGAISCNANAKISAHADIAVE
CCCEEEEEEECCEEEEEEECCCCCEEEEEHHHHHHCCCCCCEEEECCCCEEEECCCEEEE
VVTGAEILTGSTRLKAGTAQKLVLNMISTASMVGIGKVYKNLMVDVLPTNKKLEERSKRI
EEECCEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHEE
IMEATEADYETANKFYEAAEKHVKVAIVMILTNSTKEIALEKLSEAKGFVRNTIQK
EEEECCCCHHHHHHHHHHHHCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA