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The map label for this gene is dtd [H]

Identifier: 226224123

GI number: 226224123

Start: 1539378

End: 1539830

Strand: Reverse

Name: dtd [H]

Synonym: Lm4b_01532

Alternate gene names: 226224123

Gene position: 1539830-1539378 (Counterclockwise)

Preceding gene: 226224124

Following gene: 226224121

Centisome position: 52.87

GC content: 39.96

Gene sequence:

>453_bases
ATGCGTGTACTACTGCAACGGTGTTATGAAGCTTCCGTGAGTGTGGAGGAGGAAGTCATTAGCGAAATAGCTGGAGGTCT
TTGTTTATTAGTTGGATTCACCCATAAAGATACCCCAGAAACCGTGGACTATATGGCAAAAAAAATCGTTGGATTACGAA
TTTTTGAAGATGAATCCGAGAAGATGAATATTTCTTTAGCAGAACGAGGCGGCGCGATTCTTAGCGTTTCCCAGTTCACT
TTATACGCTGATGTAAGTAGAGGAAAACGTCCAAGCTTTACAAAATCCGCCCCAGCAGAAAAAGCAGAAACACTGTATGA
CTTATTTAATCAAAAACTTACAGAAGCGGGTTTTATTGTTGAAACTGGAGTATTTGGCGCAATGATGGATGTGAAAATTG
TCAATCACGGTCCAGTAACAATAATGCTCGATTCAGATGAAATGCGTAAATAA

Upstream 100 bases:

>100_bases
TCATAATATTAATCATTTACAACGTGTAGTGGATAAAATAAAACAAATTCCAGATGTTTATACAGTGAGAAGATTAATGA
ACTAAAGGAGTGGAGAAGCG

Downstream 100 bases:

>100_bases
AAAAACAATCATTCAGTCTCCTGAATGATTGTTTTTTTAATTAGAGAAGTAATTAGATAGGCCATCTGTTACTGATTCAG
CGATTTGGCTTCTGTATGAT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRVLLQRCYEASVSVEEEVISEIAGGLCLLVGFTHKDTPETVDYMAKKIVGLRIFEDESEKMNISLAERGGAILSVSQFT
LYADVSRGKRPSFTKSAPAEKAETLYDLFNQKLTEAGFIVETGVFGAMMDVKIVNHGPVTIMLDSDEMRK

Sequences:

>Translated_150_residues
MRVLLQRCYEASVSVEEEVISEIAGGLCLLVGFTHKDTPETVDYMAKKIVGLRIFEDESEKMNISLAERGGAILSVSQFT
LYADVSRGKRPSFTKSAPAEKAETLYDLFNQKLTEAGFIVETGVFGAMMDVKIVNHGPVTIMLDSDEMRK
>Mature_150_residues
MRVLLQRCYEASVSVEEEVISEIAGGLCLLVGFTHKDTPETVDYMAKKIVGLRIFEDESEKMNISLAERGGAILSVSQFT
LYADVSRGKRPSFTKSAPAEKAETLYDLFNQKLTEAGFIVETGVFGAMMDVKIVNHGPVTIMLDSDEMRK

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=43.2432432432432, Blast_Score=109, Evalue=8e-25,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=44.7552447552448, Blast_Score=129, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=41.3333333333333, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6319982, Length=151, Percent_Identity=43.7086092715232, Blast_Score=115, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281361569, Length=151, Percent_Identity=40.3973509933775, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16602; Mature: 16602

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLQRCYEASVSVEEEVISEIAGGLCLLVGFTHKDTPETVDYMAKKIVGLRIFEDESE
CHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCEEEEECCCC
KMNISLAERGGAILSVSQFTLYADVSRGKRPSFTKSAPAEKAETLYDLFNQKLTEAGFIV
EEEEEEECCCCEEEEEEHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
ETGVFGAMMDVKIVNHGPVTIMLDSDEMRK
ECCCCHHEEEEEEECCCCEEEEECCHHHCC
>Mature Secondary Structure
MRVLLQRCYEASVSVEEEVISEIAGGLCLLVGFTHKDTPETVDYMAKKIVGLRIFEDESE
CHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCEEEEECCCC
KMNISLAERGGAILSVSQFTLYADVSRGKRPSFTKSAPAEKAETLYDLFNQKLTEAGFIV
EEEEEEECCCCEEEEEEHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
ETGVFGAMMDVKIVNHGPVTIMLDSDEMRK
ECCCCHHEEEEEEECCCCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA