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The map label for this gene is opuCD

Identifier: 226224026

GI number: 226224026

Start: 1440467

End: 1441138

Strand: Reverse

Name: opuCD

Synonym: Lm4b_01434

Alternate gene names: 226224026

Gene position: 1441138-1440467 (Counterclockwise)

Preceding gene: 226224027

Following gene: 226224025

Centisome position: 49.48

GC content: 40.77

Gene sequence:

>672_bases
ATGGACACATTAAAACAATTAATTGATTATTACCAAACAAATGGAAGTTATGTCATGGAAGAGTTCTGGCGGCATTTCTT
GATGAGTGCTTACGGAGTTATCTTCGCAGCAATCATCGCAATACCGCTCGGAGTATATATTGCAAGAAAAAAACGCTTAG
CTGGCTGGGTTATCCAAATCGCTAATATCATCCAAACAATTCCGGCACTAGCAATGTTAGCCGTACTTATGCTTATAATG
GGCTTAGGGACGAATACAGTCGTCTTATCCTTATTCCTATATTCTTTACTACCAATTCTAAAAAACACCTATACGGGCAT
TAGAAACGTTGATGGCGCACTTTTAGAATCTGGTAAAGCGATGGGGATGACAAAATGGCAAGTACTACGCCTCATAGAAA
TGCCACTCGCATTATCTGTTATTATGGCAGGTATTCGAAATGCACTTGTTATTGCTATTGGTGTAGCGGCAATTGGGACA
TTCGTTGGAGCGGGAGGTCTCGGTGATATTATTGTACGCGGAACAAATGCAACAAATGGTACTGCTATCATTTTAGCTGG
TGCTATCCCAACCGCAGTTATGGCCATATTAGCCGATGTACTTCTCGGTTGGGTCGAACGCACACTAAACCCAGTTAAAA
ACAAAAGAAAATCACTAACTGAAGCCTTATAA

Upstream 100 bases:

>100_bases
ATGAAGCGGATGGCAAATTGAAAGAACCGTCCATCGTAGCGCAAGAATTCTTGCAAAAAAATAATTACTTTGAAGGTAAA
AACTAAGGAGGTGCCAAAAG

Downstream 100 bases:

>100_bases
AAATATACGAAAACACAACCTATCATTTCTATAAAACGGTTGTGTTTTTCGTTTGACAAAGAATGTTTCCCGTAGTAAAC
TTTTTATCATAAACGAAAGA

Product: betaine/carnitine/choline ABC transporter (membrane protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MDTLKQLIDYYQTNGSYVMEEFWRHFLMSAYGVIFAAIIAIPLGVYIARKKRLAGWVIQIANIIQTIPALAMLAVLMLIM
GLGTNTVVLSLFLYSLLPILKNTYTGIRNVDGALLESGKAMGMTKWQVLRLIEMPLALSVIMAGIRNALVIAIGVAAIGT
FVGAGGLGDIIVRGTNATNGTAIILAGAIPTAVMAILADVLLGWVERTLNPVKNKRKSLTEAL

Sequences:

>Translated_223_residues
MDTLKQLIDYYQTNGSYVMEEFWRHFLMSAYGVIFAAIIAIPLGVYIARKKRLAGWVIQIANIIQTIPALAMLAVLMLIM
GLGTNTVVLSLFLYSLLPILKNTYTGIRNVDGALLESGKAMGMTKWQVLRLIEMPLALSVIMAGIRNALVIAIGVAAIGT
FVGAGGLGDIIVRGTNATNGTAIILAGAIPTAVMAILADVLLGWVERTLNPVKNKRKSLTEAL
>Mature_223_residues
MDTLKQLIDYYQTNGSYVMEEFWRHFLMSAYGVIFAAIIAIPLGVYIARKKRLAGWVIQIANIIQTIPALAMLAVLMLIM
GLGTNTVVLSLFLYSLLPILKNTYTGIRNVDGALLESGKAMGMTKWQVLRLIEMPLALSVIMAGIRNALVIAIGVAAIGT
FVGAGGLGDIIVRGTNATNGTAIILAGAIPTAVMAILADVLLGWVERTLNPVKNKRKSLTEAL

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=207, Percent_Identity=35.2657004830918, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1788451, Length=213, Percent_Identity=28.169014084507, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789033, Length=183, Percent_Identity=30.6010928961749, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23973; Mature: 23973

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLKQLIDYYQTNGSYVMEEFWRHFLMSAYGVIFAAIIAIPLGVYIARKKRLAGWVIQI
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANIIQTIPALAMLAVLMLIMGLGTNTVVLSLFLYSLLPILKNTYTGIRNVDGALLESGKA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
MGMTKWQVLRLIEMPLALSVIMAGIRNALVIAIGVAAIGTFVGAGGLGDIIVRGTNATNG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCC
TAIILAGAIPTAVMAILADVLLGWVERTLNPVKNKRKSLTEAL
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTLKQLIDYYQTNGSYVMEEFWRHFLMSAYGVIFAAIIAIPLGVYIARKKRLAGWVIQI
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANIIQTIPALAMLAVLMLIMGLGTNTVVLSLFLYSLLPILKNTYTGIRNVDGALLESGKA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
MGMTKWQVLRLIEMPLALSVIMAGIRNALVIAIGVAAIGTFVGAGGLGDIIVRGTNATNG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCC
TAIILAGAIPTAVMAILADVLLGWVERTLNPVKNKRKSLTEAL
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]