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The map label for this gene is frr

Identifier: 226223915

GI number: 226223915

Start: 1323999

End: 1324556

Strand: Direct

Name: frr

Synonym: Lm4b_01322

Alternate gene names: 226223915

Gene position: 1323999-1324556 (Clockwise)

Preceding gene: 226223914

Following gene: 226223916

Centisome position: 45.46

GC content: 35.84

Gene sequence:

>558_bases
ATGAGTAAAGAAGTATTATCGAAATCCAAAGAAAAAATGGAAAAAGCAGAACAAGCATTAACAAGACAATTAGGTACAAT
CCGCGCTGGTCGTGCGAATGCATCATTACTTGACCGTTTATCTGTAGATTATTACGGAGCAGCTACTCCAGTGAACCAAA
TGGCTTCTATCAGCGTTCCTGAAGCTAGAATGTTACTAATTACACCTTACGATAAAACTATTTTAGGTGAAATTGAAAAA
GCAATTTTGAAATCAGATTTAGGTTTGACTCCAAATAATGATGGTTCTGTGCTACGTTTATCTATTCCACAATTAACGGA
AGAACGTCGTAAAGAGTTGGTTAAAGAAGTGAAAAAAGAAGCTGAAGAAGCGAAAGTTGCTGTCCGTAACATTCGTCGTG
AAGCTAATGAAGAATTGAAAAAACTAGAAAAAAATGGCGACATCACAGAAGATGATTTGCGTTCTTATGGTGAAGACGTT
CAAAAATTAACAGATGAAAGCATCAAGAACATCGATAGCATCACGAAAGACAAAGAAGCGGAAATCTTAGAAGTTTAA

Upstream 100 bases:

>100_bases
ATATTCCATTAATCGTCTTCTCGTTTACAGAACAAGGCAATAATATTAAACGTGTTATTTTAGGTGAAAAAATCGGGACT
ACTGTTAGGGGGAAAAAATA

Downstream 100 bases:

>100_bases
TTGATACTTTTACAAATAGTAACAAATAGGGTTAAACACCTTTTAAGTTGAAGCGACATTCCTAATTCTTTCCATATGTG
TTGGGTTAGGAATGTTTTTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSKEVLSKSKEKMEKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAATPVNQMASISVPEARMLLITPYDKTILGEIEK
AILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKEAEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDV
QKLTDESIKNIDSITKDKEAEILEV

Sequences:

>Translated_185_residues
MSKEVLSKSKEKMEKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAATPVNQMASISVPEARMLLITPYDKTILGEIEK
AILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKEAEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDV
QKLTDESIKNIDSITKDKEAEILEV
>Mature_184_residues
SKEVLSKSKEKMEKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAATPVNQMASISVPEARMLLITPYDKTILGEIEKA
ILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKEAEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDVQ
KLTDESIKNIDSITKDKEAEILEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=181, Percent_Identity=27.0718232044199, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=28.6666666666667, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1786368, Length=174, Percent_Identity=50.5747126436782, Blast_Score=178, Evalue=2e-46,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20756; Mature: 20625

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEVLSKSKEKMEKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAATPVNQMASISVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCC
EARMLLITPYDKTILGEIEKAILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKE
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
AEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDVQKLTDESIKNIDSITKDKEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EILEV
HHHCC
>Mature Secondary Structure 
SKEVLSKSKEKMEKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAATPVNQMASISVP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCC
EARMLLITPYDKTILGEIEKAILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKE
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
AEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDVQKLTDESIKNIDSITKDKEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EILEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]