Click here to switch to the map view.

The map label for this gene is coaX [H]

Identifier: 226222850

GI number: 226222850

Start: 225646

End: 226425

Strand: Direct

Name: coaX [H]

Synonym: Lm4b_00219

Alternate gene names: 226222850

Gene position: 225646-226425 (Clockwise)

Preceding gene: 226222849

Following gene: 226222851

Centisome position: 7.75

GC content: 41.92

Gene sequence:

>780_bases
ATGATACTTGTAATAGACGTTGGAAATACTAACTGTACTGTCGGAGTTTATGAAAAACAAAAACTTCTGAAACATTGGCG
CATGACAACAGATCGTCACCGCACATCCGATGAATTAGGAATGACAGTCTTGAACTTTTTTTCTTATGCGAATTTAACTC
CTTCTGATATTCAAGGAATTATTATTTCGTCCGTCGTTCCACCGATTATGCACGCAATGGAAACAATGTGCGTACGCTAT
TTTAATATCCGACCATTAATCGTTGGTCCAGGAATAAAAACCGGCTTAAACCTCAAAGTCGATAATCCTCGCGAAATCGG
ATCTGACCGAATCGTAAACGCCGTAGCAGCATCAGAAGAATACGGGACACCGGTTATCGTAGTCGATTTTGGCACTGCGA
CCACATTTTGCTATATCGATGAATCAGGCGTATACCAAGGTGGCGCCATCGCTCCAGGGATTATGATTTCGACCGAAGCT
CTATACAACCGCGCTGCTAAACTACCACGCGTAGATATTGCTGAATCAAACCAAATCATCGGCAAATCCACCGTGGCATC
CATGCAAGCGGGCATCTTTTATGGTTTCGTCGGCCAATGCGAAGGGATTATCGCAGAAATCAAAAAACAATCCAACGCAA
GCCCAGTAGTAGTTGCAACAGGCGGGCTCGCTCGGATGATAACAGAAAAATCTTCTGCAGTAGATATTTTAGATCCATTT
TTAACATTAAAAGGTCTAGAACTTCTATATAGAAGAAACAAACCAACTACAGAAAAATAA

Upstream 100 bases:

>100_bases
GCTTTCCCAGTCTCTTTTTTGAAGCTATATTATTCGGATTTTCCTATAAAACATGTTATGATACGTTAGAAAAATCTTCT
AAAGGACGGTATTTAAACTT

Downstream 100 bases:

>100_bases
AAGGAGTTTTATATAATGAGTGATTATTTAGTTAAAGCGTTAGCCTACGATGGCATGGCGCGTGTATATGCAGCAGTAAC
AACCGAAACAATCAAAGAAG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGIIISSVVPPIMHAMETMCVRY
FNIRPLIVGPGIKTGLNLKVDNPREIGSDRIVNAVAASEEYGTPVIVVDFGTATTFCYIDESGVYQGGAIAPGIMISTEA
LYNRAAKLPRVDIAESNQIIGKSTVASMQAGIFYGFVGQCEGIIAEIKKQSNASPVVVATGGLARMITEKSSAVDILDPF
LTLKGLELLYRRNKPTTEK

Sequences:

>Translated_259_residues
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGIIISSVVPPIMHAMETMCVRY
FNIRPLIVGPGIKTGLNLKVDNPREIGSDRIVNAVAASEEYGTPVIVVDFGTATTFCYIDESGVYQGGAIAPGIMISTEA
LYNRAAKLPRVDIAESNQIIGKSTVASMQAGIFYGFVGQCEGIIAEIKKQSNASPVVVATGGLARMITEKSSAVDILDPF
LTLKGLELLYRRNKPTTEK
>Mature_259_residues
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGIIISSVVPPIMHAMETMCVRY
FNIRPLIVGPGIKTGLNLKVDNPREIGSDRIVNAVAASEEYGTPVIVVDFGTATTFCYIDESGVYQGGAIAPGIMISTEA
LYNRAAKLPRVDIAESNQIIGKSTVASMQAGIFYGFVGQCEGIIAEIKKQSNASPVVVATGGLARMITEKSSAVDILDPF
LTLKGLELLYRRNKPTTEK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28181; Mature: 28181

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGI
CEEEEEECCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IISSVVPPIMHAMETMCVRYFNIRPLIVGPGIKTGLNLKVDNPREIGSDRIVNAVAASEE
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCHHHCCCHHHHHHHHCCCC
YGTPVIVVDFGTATTFCYIDESGVYQGGAIAPGIMISTEALYNRAAKLPRVDIAESNQII
CCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCC
GKSTVASMQAGIFYGFVGQCEGIIAEIKKQSNASPVVVATGGLARMITEKSSAVDILDPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCCCCHHHHHHH
LTLKGLELLYRRNKPTTEK
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGI
CEEEEEECCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IISSVVPPIMHAMETMCVRYFNIRPLIVGPGIKTGLNLKVDNPREIGSDRIVNAVAASEE
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCHHHCCCHHHHHHHHCCCC
YGTPVIVVDFGTATTFCYIDESGVYQGGAIAPGIMISTEALYNRAAKLPRVDIAESNQII
CCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCC
GKSTVASMQAGIFYGFVGQCEGIIAEIKKQSNASPVVVATGGLARMITEKSSAVDILDPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHCCCCCHHHHHHH
LTLKGLELLYRRNKPTTEK
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]