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The map label for this gene is hslO

Identifier: 226222851

GI number: 226222851

Start: 226441

End: 227325

Strand: Direct

Name: hslO

Synonym: Lm4b_00220

Alternate gene names: 226222851

Gene position: 226441-227325 (Clockwise)

Preceding gene: 226222850

Following gene: 226222852

Centisome position: 7.77

GC content: 41.24

Gene sequence:

>885_bases
ATGAGTGATTATTTAGTTAAAGCGTTAGCCTACGATGGCATGGCGCGTGTATATGCAGCAGTAACAACCGAAACAATCAA
AGAAGCACAAAGAAGACATGATACATGGTCCGTCTCATCCGCCGCACTTGGTAGAACGATGACAGGAACACTTTTCCTTG
GAGCAATGCAAAAAGAAGACCAAAAAATAACTGTAAAAATCGAAGGCGACGGCCCAATCGGTCCAATCGTAGCTGATAGT
AACGCACAAGGTCAAATCAGAGGATACGTAACAAATCCACACGTTCACTTCAGCGAACTAAATGAAGCTGGAAAACTTGA
CGTCCGCCGCGGCGTTGGAACATCCGGAATGCTTTCAGTTGTAAAAGATTTAGGCTTTGGAGAAAATTTCACCGGACAAA
CGCCAATTATTTCAGGTGAAATTGGTGAAGATTTTACGTATTACCTAGCAACATCTGAACAAATCAATTCCTCCGTTGGT
GTAGGAGTACTTGTTAACCCAGATGATACAATCGAAGCAGCTGGCGGTTTCATGTTGCAATTACTCCCTGGTGCGACAGA
TGAAATCATTGATGAAATTGAAAAAAATCTGACGGCTCTACCAACAGTTTCTAGAATGATTGAAGCGGGCGAAACTCCTG
AATCGATTTTAGCTAAACTTGCAGGCGGCGAAGATAAACTACAAATCTTAGAAAAAATCCCCGTTTCCTTTGAATGTAAC
TGCTCCAAAGAACGCTTTGGCAGTGCAATAATTTCACTTGGAAAAGAAGAAATTCGTTCCATGATAGAAGAGGATCACGG
CGCAGAAGCAGAATGTCATTTTTGTCGTAACGCTTACGATTTTTCAGAAGAAGAATTAGAAAAACTATACGATGAAGCTA
AATAA

Upstream 100 bases:

>100_bases
TGCAGTAGATATTTTAGATCCATTTTTAACATTAAAAGGTCTAGAACTTCTATATAGAAGAAACAAACCAACTACAGAAA
AATAAAAGGAGTTTTATATA

Downstream 100 bases:

>100_bases
AGAAAAAGGAGCACCTAATTGGTTGCTCCTTTTTAAAAGAGGTTAAACTTGACAAAACAGGTCGGAATTAATTAAACTAG
ATGAAAGACCTAAAATAGAT

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33 [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSDYLVKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKEDQKITVKIEGDGPIGPIVADS
NAQGQIRGYVTNPHVHFSELNEAGKLDVRRGVGTSGMLSVVKDLGFGENFTGQTPIISGEIGEDFTYYLATSEQINSSVG
VGVLVNPDDTIEAAGGFMLQLLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECN
CSKERFGSAIISLGKEEIRSMIEEDHGAEAECHFCRNAYDFSEEELEKLYDEAK

Sequences:

>Translated_294_residues
MSDYLVKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKEDQKITVKIEGDGPIGPIVADS
NAQGQIRGYVTNPHVHFSELNEAGKLDVRRGVGTSGMLSVVKDLGFGENFTGQTPIISGEIGEDFTYYLATSEQINSSVG
VGVLVNPDDTIEAAGGFMLQLLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECN
CSKERFGSAIISLGKEEIRSMIEEDHGAEAECHFCRNAYDFSEEELEKLYDEAK
>Mature_293_residues
SDYLVKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKEDQKITVKIEGDGPIGPIVADSN
AQGQIRGYVTNPHVHFSELNEAGKLDVRRGVGTSGMLSVVKDLGFGENFTGQTPIISGEIGEDFTYYLATSEQINSSVGV
GVLVNPDDTIEAAGGFMLQLLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECNC
SKERFGSAIISLGKEEIRSMIEEDHGAEAECHFCRNAYDFSEEELEKLYDEAK

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress [H]

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family [H]

Homologues:

Organism=Escherichia coli, GI87082260, Length=295, Percent_Identity=25.0847457627119, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153 [H]

Pfam domain/function: PF01430 HSP33 [H]

EC number: NA

Molecular weight: Translated: 31883; Mature: 31752

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYLVKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKED
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHEEEECCCCC
QKITVKIEGDGPIGPIVADSNAQGQIRGYVTNPHVHFSELNEAGKLDVRRGVGTSGMLSV
CEEEEEEECCCCCCCEEECCCCCCEEEEEEECCEEEHHHHCCCCCEEHHCCCCCHHHHHH
VKDLGFGENFTGQTPIISGEIGEDFTYYLATSEQINSSVGVGVLVNPDDTIEAAGGFMLQ
HHHCCCCCCCCCCCCEEECCCCCCEEEEEEEHHHHCCCCCEEEEECCCCCHHHCCCEEEE
LLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCEECC
CSKERFGSAIISLGKEEIRSMIEEDHGAEAECHFCRNAYDFSEEELEKLYDEAK
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDYLVKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKED
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHEEEECCCCC
QKITVKIEGDGPIGPIVADSNAQGQIRGYVTNPHVHFSELNEAGKLDVRRGVGTSGMLSV
CEEEEEEECCCCCCCEEECCCCCCEEEEEEECCEEEHHHHCCCCCEEHHCCCCCHHHHHH
VKDLGFGENFTGQTPIISGEIGEDFTYYLATSEQINSSVGVGVLVNPDDTIEAAGGFMLQ
HHHCCCCCCCCCCCCEEECCCCCCEEEEEEEHHHHCCCCCEEEEECCCCCHHHCCCEEEE
LLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCEECC
CSKERFGSAIISLGKEEIRSMIEEDHGAEAECHFCRNAYDFSEEELEKLYDEAK
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]