BacMap

Definition	Listeria monocytogenes Clip81459, complete genome.
Accession	NC_012488
Length	2,912,690

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The map label for this gene is ftsH

Identifier: 226222849

GI number: 226222849

Start: 223443

End: 225530

Strand: Direct

Name: ftsH

Synonym: Lm4b_00218

Alternate gene names: 226222849

Gene position: 223443-225530 (Clockwise)

Preceding gene: 226222848

Following gene: 226222850

Centisome position: 7.67

GC content: 41.95

Gene sequence:

>2088_bases
ATGAACAGGTTTTTTAGAAATGCGATATTTTATGTCATAATATTCCTTGTTATTATCGGGATTGTTGCTTCATTTAACTC
AAACAAAGAGGCAGCCAAAGATATTAGCTATTCAGAATTTGTGAGTAAGTTAGAAGATGGTAAAGTTAAATCCGTAGAAA
TACAGCCAGACCGTAGTGTTTATACAATCAATGGGGAATTTAAATCTAGCGATAAAAGTTCCGACGATAAAAAAACGGGT
CTTGGACAAAGCAAAACAAGCAGCACTGCTTTCACAACATACGCTTTAAACAGCGATACTTCACTAGGCGATTTGCAAAA
AACGCTTGATAAAGAAGACGTGAAAACAACAATAGTACCTGCCAAACAAAACAGCGGTTGGGTTACATTCCTAACTTCTA
TTGTACCTTTTGTAATTATCTTCATCCTCTTCTTCTTCCTAATGAGCCAGTCTCAAGGTGGCGGCGGTGGTAAAGTAATG
AGCTTTGGTAAAAGTAAAGCCAAACTTTACAACGACGACAAGAAGAAAGTTCGCTTCACAGATGTAGCTGGAGCAGACGA
GGAAAAACAAGAACTTGTTGAAGTAGTAGAATTCCTAAAAGATCCGCGTAAATTTGCGGACCTCGGCGCTCGTATTCCAA
AAGGTGTCCTTTTAGTAGGTCCTCCGGGTACTGGTAAAACCTTGCTAGCTCGTGCGGTTGCCGGTGAAGCAGGCGTGCCA
TTCTTCTCTATCTCAGGTTCAGACTTTGTAGAAATGTTTGTCGGTGTCGGTGCAAGCCGTGTCCGTGATTTATTCGAAAA
TGCGAAGAAAAATGCACCATGTATCATTTTCATTGATGAAATTGATGCAGTAGGTCGTCAACGTGGAGCAGGAATGGGCG
GCGGTCACGATGAACGTGAACAAACCCTAAACCAATTACTAGTTGAAATGGATGGTTTCGGTGGCAATGAAGGTATCATC
ATTATTGCAGCAACTAACCGTGCAGACGTACTTGACCCAGCACTTCTTCGTCCAGGCCGTTTTGACCGCCAAATCATGGT
TGATCGTCCAGACGTAAAAGGCCGTGAAGCAGTACTTCGCGTTCATGCTCGTAACAAACCACTTGCTAAAAGTGTTGATT
TAAAAGCAATCGCTCAACGTACACCGGGATTCTCTGGTGCCGATTTAGAAAACTTACTGAATGAAGCAGCACTCGTTGCC
GCACGTTCCGATAAGAAAGAAATAGATATGAGTGACCTCGATGAAGCTAGTGACCGCGTAATTGCCGGACCAGCTAAGAA
AAATCGAGTTATCTCTGAAAAAGAACGCCGCACAGTCGCATATCATGAAGGTGGTCACGTTATCGTCGGAATGGTACTTG
ATGAAGCGGAAGTTGTGCATAAAGTTACCATTGTTCCTCGTGGACAAGCTGGTGGTTATGCCGTAATGTTACCAAAAGAA
GATCGCTTCCTAATGACGAAAGCTGAGTTAATGGACCGTATCACTGGTTTACTCGGTGGACGCGTAGCCGAAGAAGTTAC
TTTTGGTGAAGTAACAACTGGTGCAAGTAATGACTTTGAACGTGCAACCGAACTTGCTCGCCGCATGGTAACTGAATGGG
GTATGAGTGACAAGATTGGACCACTTCAATTCACTTCTGGTAACGGTCAAGTATTTATGGGCCGCGATTTCGGTAGCGAC
AAAGGATATTCCGATAAAATCGCCTACGAAATTGATACAGAAGTTCAGAGCTTAATCCGCTACTGTTATGACCGCGCTAA
AACAATCATTACAGAACACCAAGAACAACACAAACTTATCGCGGAAACATTACTAAAAGTAGAAACTTTAGATGCTCGCC
AAATTCGTTCCCTATTTGATGACGGTGTAATGCCTCCAGATATCGATACGATTGACGTAGAAGCAGAATATCCTTCCGAA
AAAGACGAAGAAGTAGCAGGTAAATCTTTTGAAGAAGAAAAAGAAGAGTTAAAAGAAGAAGAAAAAATCGAAGAACCAAA
AGAAGAACCAAAAGAAGAACCAAAAGAAGTAACTTCGGAAGATGCTCCAAACATTGAGCAAACACCAAACGATAAAAAAG
ACGAATAA

Upstream 100 bases:

>100_bases
AAAATTGTTTCTAAATCTGCTATTAGCCAAAAACAACTTTTAAAGGGGTAAAGTCCAGAAAAAGTAAGAATCCAAGCTCT
TGCGTGGGAGGAGGTAAGGA

Downstream 100 bases:

>100_bases
AATCAAAGAGGCTGGGCTTTCCCAGTCTCTTTTTTGAAGCTATATTATTCGGATTTTCCTATAAAACATGTTATGATACG
TTAGAAAAATCTTCTAAAGG

Product: cell division protein ftsH

Products: NA

Alternate protein names: Cell division protease FtsH [H]

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MNRFFRNAIFYVIIFLVIIGIVASFNSNKEAAKDISYSEFVSKLEDGKVKSVEIQPDRSVYTINGEFKSSDKSSDDKKTG
LGQSKTSSTAFTTYALNSDTSLGDLQKTLDKEDVKTTIVPAKQNSGWVTFLTSIVPFVIIFILFFFLMSQSQGGGGGKVM
SFGKSKAKLYNDDKKKVRFTDVAGADEEKQELVEVVEFLKDPRKFADLGARIPKGVLLVGPPGTGKTLLARAVAGEAGVP
FFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFGGNEGII
IIAATNRADVLDPALLRPGRFDRQIMVDRPDVKGREAVLRVHARNKPLAKSVDLKAIAQRTPGFSGADLENLLNEAALVA
ARSDKKEIDMSDLDEASDRVIAGPAKKNRVISEKERRTVAYHEGGHVIVGMVLDEAEVVHKVTIVPRGQAGGYAVMLPKE
DRFLMTKAELMDRITGLLGGRVAEEVTFGEVTTGASNDFERATELARRMVTEWGMSDKIGPLQFTSGNGQVFMGRDFGSD
KGYSDKIAYEIDTEVQSLIRYCYDRAKTIITEHQEQHKLIAETLLKVETLDARQIRSLFDDGVMPPDIDTIDVEAEYPSE
KDEEVAGKSFEEEKEELKEEEKIEEPKEEPKEEPKEVTSEDAPNIEQTPNDKKDE

Sequences:

>Translated_695_residues
MNRFFRNAIFYVIIFLVIIGIVASFNSNKEAAKDISYSEFVSKLEDGKVKSVEIQPDRSVYTINGEFKSSDKSSDDKKTG
LGQSKTSSTAFTTYALNSDTSLGDLQKTLDKEDVKTTIVPAKQNSGWVTFLTSIVPFVIIFILFFFLMSQSQGGGGGKVM
SFGKSKAKLYNDDKKKVRFTDVAGADEEKQELVEVVEFLKDPRKFADLGARIPKGVLLVGPPGTGKTLLARAVAGEAGVP
FFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFGGNEGII
IIAATNRADVLDPALLRPGRFDRQIMVDRPDVKGREAVLRVHARNKPLAKSVDLKAIAQRTPGFSGADLENLLNEAALVA
ARSDKKEIDMSDLDEASDRVIAGPAKKNRVISEKERRTVAYHEGGHVIVGMVLDEAEVVHKVTIVPRGQAGGYAVMLPKE
DRFLMTKAELMDRITGLLGGRVAEEVTFGEVTTGASNDFERATELARRMVTEWGMSDKIGPLQFTSGNGQVFMGRDFGSD
KGYSDKIAYEIDTEVQSLIRYCYDRAKTIITEHQEQHKLIAETLLKVETLDARQIRSLFDDGVMPPDIDTIDVEAEYPSE
KDEEVAGKSFEEEKEELKEEEKIEEPKEEPKEEPKEVTSEDAPNIEQTPNDKKDE
>Mature_695_residues
MNRFFRNAIFYVIIFLVIIGIVASFNSNKEAAKDISYSEFVSKLEDGKVKSVEIQPDRSVYTINGEFKSSDKSSDDKKTG
LGQSKTSSTAFTTYALNSDTSLGDLQKTLDKEDVKTTIVPAKQNSGWVTFLTSIVPFVIIFILFFFLMSQSQGGGGGKVM
SFGKSKAKLYNDDKKKVRFTDVAGADEEKQELVEVVEFLKDPRKFADLGARIPKGVLLVGPPGTGKTLLARAVAGEAGVP
FFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFGGNEGII
IIAATNRADVLDPALLRPGRFDRQIMVDRPDVKGREAVLRVHARNKPLAKSVDLKAIAQRTPGFSGADLENLLNEAALVA
ARSDKKEIDMSDLDEASDRVIAGPAKKNRVISEKERRTVAYHEGGHVIVGMVLDEAEVVHKVTIVPRGQAGGYAVMLPKE
DRFLMTKAELMDRITGLLGGRVAEEVTFGEVTTGASNDFERATELARRMVTEWGMSDKIGPLQFTSGNGQVFMGRDFGSD
KGYSDKIAYEIDTEVQSLIRYCYDRAKTIITEHQEQHKLIAETLLKVETLDARQIRSLFDDGVMPPDIDTIDVEAEYPSE
KDEEVAGKSFEEEKEELKEEEKIEEPKEEPKEEPKEVTSEDAPNIEQTPNDKKDE

Specific function: In vitro partially degrades Spo0E, the phosphatase that acts on Spo0A-P. Recognition requires the last 14 residues of Spo0E [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side (Probable). Note=Accumulates in the midcell septum during vegetative cell division. At the onset of sporulation appears at positions near the cell poles that may coincide with future division si

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=631, Percent_Identity=42.3137876386688, Blast_Score=471, Evalue=1e-132,
Organism=Homo sapiens, GI21327685, Length=449, Percent_Identity=50.5567928730512, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI7657689, Length=449, Percent_Identity=50.5567928730512, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI4507173, Length=626, Percent_Identity=37.3801916932907, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI24497435, Length=254, Percent_Identity=43.3070866141732, Blast_Score=213, Evalue=6e-55,
Organism=Homo sapiens, GI4506209, Length=256, Percent_Identity=42.578125, Blast_Score=210, Evalue=4e-54,
Organism=Homo sapiens, GI21361144, Length=245, Percent_Identity=42.0408163265306, Blast_Score=203, Evalue=6e-52,
Organism=Homo sapiens, GI195539395, Length=255, Percent_Identity=41.9607843137255, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI6005942, Length=226, Percent_Identity=43.3628318584071, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI89064750, Length=254, Percent_Identity=41.3385826771654, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI5729991, Length=254, Percent_Identity=41.3385826771654, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI24430155, Length=254, Percent_Identity=41.3385826771654, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI24430151, Length=244, Percent_Identity=39.7540983606557, Blast_Score=193, Evalue=6e-49,
Organism=Homo sapiens, GI45643123, Length=281, Percent_Identity=37.7224199288256, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI45643125, Length=281, Percent_Identity=37.7224199288256, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI157671927, Length=233, Percent_Identity=40.7725321888412, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI4505725, Length=223, Percent_Identity=40.8071748878924, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI40806173, Length=308, Percent_Identity=37.6623376623377, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI229577436, Length=248, Percent_Identity=41.5322580645161, Blast_Score=173, Evalue=6e-43,
Organism=Homo sapiens, GI153792536, Length=255, Percent_Identity=38.4313725490196, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI24497618, Length=256, Percent_Identity=38.28125, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI5901990, Length=241, Percent_Identity=41.49377593361, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI226371754, Length=237, Percent_Identity=38.3966244725738, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI14149767, Length=236, Percent_Identity=38.9830508474576, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI62177112, Length=236, Percent_Identity=38.9830508474576, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI194018488, Length=262, Percent_Identity=38.5496183206107, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI17865802, Length=236, Percent_Identity=37.7118644067797, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI11875211, Length=266, Percent_Identity=36.4661654135338, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI40806170, Length=266, Percent_Identity=36.4661654135338, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI7019569, Length=262, Percent_Identity=33.969465648855, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI31377644, Length=243, Percent_Identity=36.2139917695473, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI31742536, Length=236, Percent_Identity=35.1694915254237, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI112789543, Length=236, Percent_Identity=35.1694915254237, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI156564401, Length=233, Percent_Identity=39.0557939914163, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310125282, Length=233, Percent_Identity=38.6266094420601, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI310125280, Length=233, Percent_Identity=38.6266094420601, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI64084766, Length=226, Percent_Identity=28.7610619469027, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI116292174, Length=255, Percent_Identity=30.1960784313725, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4757852, Length=158, Percent_Identity=30.379746835443, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI119964730, Length=158, Percent_Identity=30.379746835443, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1789568, Length=616, Percent_Identity=50.1623376623377, Blast_Score=616, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71994521, Length=617, Percent_Identity=44.2463533225284, Blast_Score=452, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17554264, Length=437, Percent_Identity=49.8855835240275, Blast_Score=423, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI115534323, Length=640, Percent_Identity=38.75, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17554786, Length=251, Percent_Identity=45.0199203187251, Blast_Score=221, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI25144281, Length=251, Percent_Identity=44.6215139442231, Blast_Score=215, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI25144278, Length=251, Percent_Identity=44.6215139442231, Blast_Score=214, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17508701, Length=246, Percent_Identity=43.0894308943089, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17563248, Length=256, Percent_Identity=41.796875, Blast_Score=205, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI17563250, Length=244, Percent_Identity=41.3934426229508, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71987364, Length=261, Percent_Identity=40.2298850574713, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71987372, Length=261, Percent_Identity=40.2298850574713, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17532375, Length=232, Percent_Identity=40.5172413793103, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17505546, Length=244, Percent_Identity=41.8032786885246, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17531535, Length=235, Percent_Identity=45.1063829787234, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17554784, Length=254, Percent_Identity=40.5511811023622, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17537217, Length=258, Percent_Identity=39.922480620155, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17508053, Length=300, Percent_Identity=35, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI193206114, Length=245, Percent_Identity=41.6326530612245, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI133931034, Length=245, Percent_Identity=41.6326530612245, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI193206116, Length=245, Percent_Identity=41.6326530612245, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI25153574, Length=231, Percent_Identity=39.8268398268398, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI193209502, Length=231, Percent_Identity=39.8268398268398, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=47.2727272727273, Blast_Score=149, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=47.2727272727273, Blast_Score=149, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI86561515, Length=236, Percent_Identity=37.7118644067797, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25146157, Length=249, Percent_Identity=40.9638554216867, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562804, Length=252, Percent_Identity=35.3174603174603, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI133901662, Length=212, Percent_Identity=41.0377358490566, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI133901658, Length=212, Percent_Identity=41.0377358490566, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17508421, Length=263, Percent_Identity=36.5019011406844, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI32563584, Length=242, Percent_Identity=37.1900826446281, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541226, Length=221, Percent_Identity=37.5565610859729, Blast_Score=122, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17541224, Length=221, Percent_Identity=37.5565610859729, Blast_Score=122, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17560432, Length=417, Percent_Identity=27.8177458033573, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71990340, Length=160, Percent_Identity=32.5, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71990335, Length=160, Percent_Identity=32.5, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323736, Length=566, Percent_Identity=45.9363957597173, Blast_Score=480, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6320854, Length=630, Percent_Identity=41.9047619047619, Blast_Score=459, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325281, Length=444, Percent_Identity=45.945945945946, Blast_Score=396, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321390, Length=241, Percent_Identity=44.3983402489627, Blast_Score=215, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6322704, Length=253, Percent_Identity=42.6877470355731, Blast_Score=210, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6324691, Length=256, Percent_Identity=41.015625, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320077, Length=245, Percent_Identity=44.4897959183673, Blast_Score=201, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6320197, Length=251, Percent_Identity=38.2470119521912, Blast_Score=197, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=42.2764227642276, Blast_Score=194, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6320602, Length=250, Percent_Identity=43.2, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322651, Length=257, Percent_Identity=37.3540856031128, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323429, Length=231, Percent_Identity=41.991341991342, Blast_Score=171, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6321709, Length=258, Percent_Identity=38.7596899224806, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6322994, Length=231, Percent_Identity=35.9307359307359, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324000, Length=230, Percent_Identity=39.1304347826087, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6325431, Length=274, Percent_Identity=35.4014598540146, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6321465, Length=233, Percent_Identity=37.7682403433476, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=36.5740740740741, Blast_Score=128, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6325183, Length=256, Percent_Identity=34.375, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320887, Length=255, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320583, Length=159, Percent_Identity=31.4465408805031, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574878, Length=619, Percent_Identity=43.4571890145396, Blast_Score=471, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24665814, Length=618, Percent_Identity=43.5275080906149, Blast_Score=471, Evalue=1e-133,
Organism=Drosophila melanogaster, GI24658770, Length=494, Percent_Identity=46.3562753036437, Blast_Score=439, Evalue=1e-123,
Organism=Drosophila melanogaster, GI24639391, Length=643, Percent_Identity=39.0357698289269, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI161076486, Length=225, Percent_Identity=44.8888888888889, Blast_Score=215, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17137560, Length=225, Percent_Identity=44.8888888888889, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI161076488, Length=225, Percent_Identity=44.8888888888889, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19920408, Length=254, Percent_Identity=43.3070866141732, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI45554047, Length=342, Percent_Identity=40.0584795321637, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24651451, Length=251, Percent_Identity=44.2231075697211, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI17137738, Length=256, Percent_Identity=42.96875, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI17738151, Length=246, Percent_Identity=41.4634146341463, Blast_Score=203, Evalue=4e-52,
Organism=Drosophila melanogaster, GI24649446, Length=244, Percent_Identity=40.1639344262295, Blast_Score=194, Evalue=3e-49,
Organism=Drosophila melanogaster, GI281361487, Length=248, Percent_Identity=41.5322580645161, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24652279, Length=189, Percent_Identity=47.0899470899471, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24640100, Length=253, Percent_Identity=40.3162055335968, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI18860063, Length=242, Percent_Identity=42.5619834710744, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24663015, Length=255, Percent_Identity=40, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24660075, Length=228, Percent_Identity=42.5438596491228, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI281365776, Length=228, Percent_Identity=42.5438596491228, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI45552965, Length=228, Percent_Identity=42.5438596491228, Blast_Score=186, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24656820, Length=244, Percent_Identity=43.0327868852459, Blast_Score=186, Evalue=7e-47,
Organism=Drosophila melanogaster, GI24656825, Length=244, Percent_Identity=43.0327868852459, Blast_Score=185, Evalue=8e-47,
Organism=Drosophila melanogaster, GI19921202, Length=245, Percent_Identity=37.9591836734694, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281363136, Length=235, Percent_Identity=40.8510638297872, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI78707192, Length=235, Percent_Identity=40.8510638297872, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24644145, Length=234, Percent_Identity=41.025641025641, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI18859657, Length=236, Percent_Identity=40.2542372881356, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21355121, Length=241, Percent_Identity=34.4398340248963, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281360136, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24644411, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360146, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360138, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360142, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21357333, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360144, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281360140, Length=238, Percent_Identity=37.8151260504202, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571849, Length=233, Percent_Identity=41.6309012875536, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28571847, Length=233, Percent_Identity=41.6309012875536, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI20129529, Length=235, Percent_Identity=36.5957446808511, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24581396, Length=243, Percent_Identity=37.037037037037, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI17864540, Length=212, Percent_Identity=41.0377358490566, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28573010, Length=216, Percent_Identity=39.8148148148148, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI20129423, Length=231, Percent_Identity=35.0649350649351, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24639486, Length=204, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI20129417, Length=154, Percent_Identity=33.1168831168831, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24583262, Length=154, Percent_Identity=33.1168831168831, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 76662; Mature: 76662

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFFRNAIFYVIIFLVIIGIVASFNSNKEAAKDISYSEFVSKLEDGKVKSVEIQPDRSV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHCCCCEEEEEECCCCEE
YTINGEFKSSDKSSDDKKTGLGQSKTSSTAFTTYALNSDTSLGDLQKTLDKEDVKTTIVP
EEECCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCHHCCEEEEEE
AKQNSGWVTFLTSIVPFVIIFILFFFLMSQSQGGGGGKVMSFGKSKAKLYNDDKKKVRFT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHCCCCCCEEEEE
DVAGADEEKQELVEVVEFLKDPRKFADLGARIPKGVLLVGPPGTGKTLLARAVAGEAGVP
ECCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCC
FFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAGMGGGHDERE
EEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHCCCCCCCCCHHHH
QTLNQLLVEMDGFGGNEGIIIIAATNRADVLDPALLRPGRFDRQIMVDRPDVKGREAVLR
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCCCCHHEEE
VHARNKPLAKSVDLKAIAQRTPGFSGADLENLLNEAALVAARSDKKEIDMSDLDEASDRV
EECCCCCCHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCE
IAGPAKKNRVISEKERRTVAYHEGGHVIVGMVLDEAEVVHKVTIVPRGQAGGYAVMLPKE
EECCCHHCCCCCHHHCCEEEEECCCCEEEEEEECCHHHHEEEEEEECCCCCCEEEEECCC
DRFLMTKAELMDRITGLLGGRVAEEVTFGEVTTGASNDFERATELARRMVTEWGMSDKIG
CCEEHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCC
PLQFTSGNGQVFMGRDFGSDKGYSDKIAYEIDTEVQSLIRYCYDRAKTIITEHQEQHKLI
CEEEECCCCEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AETLLKVETLDARQIRSLFDDGVMPPDIDTIDVEAEYPSEKDEEVAGKSFEEEKEELKEE
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHHH
EKIEEPKEEPKEEPKEVTSEDAPNIEQTPNDKKDE
HHHCCHHHCHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNRFFRNAIFYVIIFLVIIGIVASFNSNKEAAKDISYSEFVSKLEDGKVKSVEIQPDRSV
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHCCCCEEEEEECCCCEE
YTINGEFKSSDKSSDDKKTGLGQSKTSSTAFTTYALNSDTSLGDLQKTLDKEDVKTTIVP
EEECCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCHHCCEEEEEE
AKQNSGWVTFLTSIVPFVIIFILFFFLMSQSQGGGGGKVMSFGKSKAKLYNDDKKKVRFT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHCCCCCCEEEEE
DVAGADEEKQELVEVVEFLKDPRKFADLGARIPKGVLLVGPPGTGKTLLARAVAGEAGVP
ECCCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCC
FFSISGSDFVEMFVGVGASRVRDLFENAKKNAPCIIFIDEIDAVGRQRGAGMGGGHDERE
EEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHCCCCCCCCCHHHH
QTLNQLLVEMDGFGGNEGIIIIAATNRADVLDPALLRPGRFDRQIMVDRPDVKGREAVLR
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEECCCCCCCCHHEEE
VHARNKPLAKSVDLKAIAQRTPGFSGADLENLLNEAALVAARSDKKEIDMSDLDEASDRV
EECCCCCCHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCE
IAGPAKKNRVISEKERRTVAYHEGGHVIVGMVLDEAEVVHKVTIVPRGQAGGYAVMLPKE
EECCCHHCCCCCHHHCCEEEEECCCCEEEEEEECCHHHHEEEEEEECCCCCCEEEEECCC
DRFLMTKAELMDRITGLLGGRVAEEVTFGEVTTGASNDFERATELARRMVTEWGMSDKIG
CCEEHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCC
PLQFTSGNGQVFMGRDFGSDKGYSDKIAYEIDTEVQSLIRYCYDRAKTIITEHQEQHKLI
CEEEECCCCEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AETLLKVETLDARQIRSLFDDGVMPPDIDTIDVEAEYPSEKDEEVAGKSFEEEKEELKEE
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHCCCHHHHHHHHHHH
EKIEEPKEEPKEEPKEVTSEDAPNIEQTPNDKKDE
HHHCCHHHCHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]