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The map label for this gene is gap [H]

Identifier: 225853182

GI number: 225853182

Start: 1686579

End: 1687586

Strand: Direct

Name: gap [H]

Synonym: BMEA_A1781

Alternate gene names: 225853182

Gene position: 1686579-1687586 (Clockwise)

Preceding gene: 225853181

Following gene: 225853183

Centisome position: 79.34

GC content: 58.33

Gene sequence:

>1008_bases
ATGGCAGTTCGCGTCGCAATCAACGGTTTTGGCCGCATTGGCCGTAACATCCTTCGCGCCATCGTGGAATCGGGGCGCAC
CGACATTCAGGTCGTCGCCATCAACGATCTCGGCCCGGTCGAAACCAACGCACATCTTCTGCGTTATGACAGCGTTCATG
GCCGTTTCCCCAAGGAAGTGGAGGTTGCAGGCGATACGATCGATGTTGGCTACGGCCCGATCAAGGTTCATGCCGTCCGC
AACCCGGCCGAACTGCCGTGGAAGGAAGAAAACGTCGATATCGCCCTTGAATGCACCGGCATTTTCACCTCGCGCGACAA
GGCAGCACTTCATCTTGAAGCTGGCGCCAAGCGCGTCATCGTCTCCGCTCCCGCAGACGGTGCCGATCTCACCGTCGTCT
ATGGTGTCAACAACGACAAGCTGACGAAGGACCATCTGGTCATCTCCAACGCTTCGTGTACCACCAACTGCCTTGCGCCG
GTGGCTCAGGTTCTCAACGATACTATCGGTATCGAAAAGGGCTTTATGACCACGATCCACTCCTATACGGGCGACCAGCC
GACGCTGGACACCATGCACAAGGATCTCTACCGCGCCCGCGCCGCTGCCCTTTCCATGATCCCGACCTCGACGGGTGCGG
CCAAGGCCGTCGGTCTCGTTCTGCCGGAACTGAAAGGCAAGCTCTACGGCGTTGCCATTCGCGTCCCGACCCCAAATGTC
TCGGTCGTTGATCTCACCTTCATCGCCAAGCGTGAAACCACCGTTGAAGAAGTCAACAATGCGATCCGCGAAGCCGCCAA
TGGCCGCCTCAAGGGCATTCTCGGCTATACCGATGAGAAGCTCGTCTCGCACGACTTCAACCACGATTCCCATTCCTCGG
TCTTCCACACCGACCAGACCAAGGTTATGGACGGCACCATGGTGCGTATCCTGTCGTGGTACGACAATGAATGGGGCTTC
TCCAGCCGCATGAGCGACACCGCCGTCGCTTTGGGCAAGCTGATCTGA

Upstream 100 bases:

>100_bases
TCCATTCCAGTTCGGTCGAGCGAATCCTGTTCGACTTGTCCGTTCCAATGGAGTTTTGAAGCACTGCGTGTGCAATACCC
TATCGGGAGATTAGAAGAAA

Downstream 100 bases:

>100_bases
TAACGGCAACGCCTCTCCTTCACTGGCGAGGCGTTTTCATTTCTTGATAAGGACCGAGAGAAGAAACATGATGTTCCGCA
CCCTTGACGATGCCAATGTC

Product: glyceraldehyde-3-phosphate dehydrogenase type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MAVRVAINGFGRIGRNILRAIVESGRTDIQVVAINDLGPVETNAHLLRYDSVHGRFPKEVEVAGDTIDVGYGPIKVHAVR
NPAELPWKEENVDIALECTGIFTSRDKAALHLEAGAKRVIVSAPADGADLTVVYGVNNDKLTKDHLVISNASCTTNCLAP
VAQVLNDTIGIEKGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLYGVAIRVPTPNV
SVVDLTFIAKRETTVEEVNNAIREAANGRLKGILGYTDEKLVSHDFNHDSHSSVFHTDQTKVMDGTMVRILSWYDNEWGF
SSRMSDTAVALGKLI

Sequences:

>Translated_335_residues
MAVRVAINGFGRIGRNILRAIVESGRTDIQVVAINDLGPVETNAHLLRYDSVHGRFPKEVEVAGDTIDVGYGPIKVHAVR
NPAELPWKEENVDIALECTGIFTSRDKAALHLEAGAKRVIVSAPADGADLTVVYGVNNDKLTKDHLVISNASCTTNCLAP
VAQVLNDTIGIEKGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLYGVAIRVPTPNV
SVVDLTFIAKRETTVEEVNNAIREAANGRLKGILGYTDEKLVSHDFNHDSHSSVFHTDQTKVMDGTMVRILSWYDNEWGF
SSRMSDTAVALGKLI
>Mature_334_residues
AVRVAINGFGRIGRNILRAIVESGRTDIQVVAINDLGPVETNAHLLRYDSVHGRFPKEVEVAGDTIDVGYGPIKVHAVRN
PAELPWKEENVDIALECTGIFTSRDKAALHLEAGAKRVIVSAPADGADLTVVYGVNNDKLTKDHLVISNASCTTNCLAPV
AQVLNDTIGIEKGFMTTIHSYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLYGVAIRVPTPNVS
VVDLTFIAKRETTVEEVNNAIREAANGRLKGILGYTDEKLVSHDFNHDSHSSVFHTDQTKVMDGTMVRILSWYDNEWGFS
SRMSDTAVALGKLI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=326, Percent_Identity=46.319018404908, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI7657116, Length=326, Percent_Identity=45.398773006135, Blast_Score=279, Evalue=3e-75,
Organism=Escherichia coli, GI1789295, Length=336, Percent_Identity=47.9166666666667, Blast_Score=324, Evalue=5e-90,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=48.9296636085627, Blast_Score=308, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=48.3383685800604, Blast_Score=301, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=47.7341389728097, Blast_Score=298, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI32566163, Length=331, Percent_Identity=48.3383685800604, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=331, Percent_Identity=48.3383685800604, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6321631, Length=328, Percent_Identity=51.219512195122, Blast_Score=326, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=50.3048780487805, Blast_Score=320, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=48.780487804878, Blast_Score=315, Evalue=4e-87,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=49.5384615384615, Blast_Score=303, Evalue=8e-83,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=49.5384615384615, Blast_Score=303, Evalue=8e-83,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=48.9230769230769, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=48.9230769230769, Blast_Score=302, Evalue=3e-82,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=43.558282208589, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36286; Mature: 36155

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRVAINGFGRIGRNILRAIVESGRTDIQVVAINDLGPVETNAHLLRYDSVHGRFPKEV
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCEE
EVAGDTIDVGYGPIKVHAVRNPAELPWKEENVDIALECTGIFTSRDKAALHLEAGAKRVI
EECCCEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEEECCCCEEE
VSAPADGADLTVVYGVNNDKLTKDHLVISNASCTTNCLAPVAQVLNDTIGIEKGFMTTIH
EECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
SYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLYGVAIRVPTPNV
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCC
SVVDLTFIAKRETTVEEVNNAIREAANGRLKGILGYTDEKLVSHDFNHDSHSSVFHTDQT
EEEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCCEEECCCC
KVMDGTMVRILSWYDNEWGFSSRMSDTAVALGKLI
EECCCCEEEEEEHHCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
AVRVAINGFGRIGRNILRAIVESGRTDIQVVAINDLGPVETNAHLLRYDSVHGRFPKEV
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCEE
EVAGDTIDVGYGPIKVHAVRNPAELPWKEENVDIALECTGIFTSRDKAALHLEAGAKRVI
EECCCEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEEECCCCEEE
VSAPADGADLTVVYGVNNDKLTKDHLVISNASCTTNCLAPVAQVLNDTIGIEKGFMTTIH
EECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
SYTGDQPTLDTMHKDLYRARAAALSMIPTSTGAAKAVGLVLPELKGKLYGVAIRVPTPNV
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCC
SVVDLTFIAKRETTVEEVNNAIREAANGRLKGILGYTDEKLVSHDFNHDSHSSVFHTDQT
EEEEEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCCCCEEECCCC
KVMDGTMVRILSWYDNEWGFSSRMSDTAVALGKLI
EECCCCEEEEEEHHCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]