Click here to switch to the map view.

The map label for this gene is tkt [H]

Identifier: 225853181

GI number: 225853181

Start: 1684447

End: 1686438

Strand: Direct

Name: tkt [H]

Synonym: BMEA_A1780

Alternate gene names: 225853181

Gene position: 1684447-1686438 (Clockwise)

Preceding gene: 225853175

Following gene: 225853182

Centisome position: 79.24

GC content: 60.04

Gene sequence:

>1992_bases
ATGACCAATACCGACAAACAAAACCAGATGGCTAATGCAATCCGCTTCCTCTCCATGGATGCGGTGGAGAAGGCCAATTC
GGGCCACCCCGGCCTGCCGATGGGCGCAGCCGATATAGCGACGACGCTTTATACCCGTTTCCTCTCGCACGACCCGAAAA
ACCCGCACTGGCCGGACCGCGACCGTTTCGTGCTTTCCGCCGGCCACGGCTCGATGCTGCTCTATTCGCTGCTCTATCTT
TCGGGCTACGAAGACATCACCATCGATGAAATCAAGAAATTCCGCCAGCTTGGCAGCCGCACCGCGGGCCACCCTGAATA
TGGCCATGCCGCTGGCATCGAAACGACGACCGGCCCGCTCGGACAGGGTATTGCCAATGCCGTCGGCATGGCGATTTCCG
AACGCATCCTGAATGCCCAGTTCGGTGACAGCCTCGTCAATCATTATACCTATGCGCTCGTCGGCGACGGCTGCCTCATG
GAAGGCATCAGCCAGGAAGCCATCGCGCTTGCGGGACACCTGAAGCTCAACAAGCTGATCGTGCTCTGGGATGACAACAA
CATCTCGATCGACGGCCCGATCACGCTTTCCGACAATACCGATCAGCCAGCCCGTTTCGCCGCTTCCGGCTGGAACACCA
TGGCTGTCGACGGTCACGACCAGGATGCGATTGCCAAGGCCATCGAACTGGCCCGGGTCTCCGACCGCCCGACGCTGATC
GCCTGCAAGACGACCATCGGTTTCGGTGCTCCGAACAAGGCTGGCACCAACAAGGTGCACGGCTCACCGCTTGGCGCGGA
AGAAATCGCCGCCACGCGCAAGGCGCTGGGCTGGTCTTCCGAACCTTTCGTCGTTCCGGCTGAAGTTCTGGACGCCTGGC
GCGTCGCGGGCCTCAACGCCGCCAAGAAGCGCCTGGAATGGGAAAAGCGCCTTTCTGCCGTAGAAGCGGAAACCCGCGCC
GAATTCGAGCGCCGCATGCGTGGCGAGCTGCCTTCCGGTTTCGATGCTGCAATCGTCGAATACAAGAAGAAGCTTTCCGC
CGACAAGCCGAAGGTTGCCACCCGCAAGTCGTCCGAAATGGCGCTGGAAGTCATCAACGGTGTCGTGCCGGAAACCGTAG
GCGGCTCTGCCGACCTTACCGGCTCCAACAACACCAAGACCAGCCAGACCAAGGCTGTCACGCCGGAAAACTATGATGGC
CGTTATATCCATTACGGCATCCGCGAGCTTGGCATGGCTGCAGCGATGAACGGCATCACGCTGCATGGCGGCCTGATCCC
CTATTCCGGCACCTTCCTGTGCTTCTCCGATTATGCGCGTCCGGCCATGCGTCTTTCCTCGCTGATGGGCATTCGCGTCG
TCTATGTGATGACGCATGATTCCATCGGTCTTGGCGAAGACGGCCCGACCCATCAGCCGGTCGAACATCTCGCCGCACTG
CGCGCCATTCCGAACCACAATGTCTTCCGTCCGGCAGACGCTGTGGAAACGGCGGAATGCTGGCAGCTTGCGCTGCATTC
AAGGAAGACGCCATCCACGCTGGCTTTGACCCGCCAGAACCTGCCGACGGTCCGCACCGAGCATCGCGAAGAAAACCTTT
GCGCTTTCGGCGCCTACGAACTTGCCGCCGCCAGCAGCGACGCCAAGGTGACGATCTTCGCAACGGGCTCGGAAGTGGAA
ATTGCGCTGAAGGCCCGCGATCTTCTGGAAGGCAAGGGCATTGCCACCCGCGTCGTTTCGGTGCCGTGCTTTGAGCTTTT
CGAGCAGCAGAGCGACACCTACAAGGAAGCGACCATTGGCGATGCGCCAGTCAAGCTTGCCATTGAAGCGGCCATCTCGC
TCGGCTGGGAACGCTTCATCGGCGAAAACGGCATCTTCATCGGCATGAAGGGCTTCGGCGCTTCGGGTGAGATCAATGAT
CTCTACAAGCATTTCGGCATTACGGCGGAACATGCCGTCGAAGCTGCGGAAAAGAAGCTCAACGCTGCATGA

Upstream 100 bases:

>100_bases
ATCCCGAAAAGCGGCTGACGGTTTTCGCTGGAGATTGTGTTCAGGTAAAAGGCATCGCCGCAACCCCGTTAAACCCTCCC
AAGGAAAGACGGCTGAGACC

Downstream 100 bases:

>100_bases
TTTTGAAACGCCGGTGCGACAAAGCGCCAGCGTTTAAGTTTCCATTCCAGTTCGGTCGAGCGAATCCTGTTCGACTTGTC
CGTTCCAATGGAGTTTTGAA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 663; Mature: 662

Protein sequence:

>663_residues
MTNTDKQNQMANAIRFLSMDAVEKANSGHPGLPMGAADIATTLYTRFLSHDPKNPHWPDRDRFVLSAGHGSMLLYSLLYL
SGYEDITIDEIKKFRQLGSRTAGHPEYGHAAGIETTTGPLGQGIANAVGMAISERILNAQFGDSLVNHYTYALVGDGCLM
EGISQEAIALAGHLKLNKLIVLWDDNNISIDGPITLSDNTDQPARFAASGWNTMAVDGHDQDAIAKAIELARVSDRPTLI
ACKTTIGFGAPNKAGTNKVHGSPLGAEEIAATRKALGWSSEPFVVPAEVLDAWRVAGLNAAKKRLEWEKRLSAVEAETRA
EFERRMRGELPSGFDAAIVEYKKKLSADKPKVATRKSSEMALEVINGVVPETVGGSADLTGSNNTKTSQTKAVTPENYDG
RYIHYGIRELGMAAAMNGITLHGGLIPYSGTFLCFSDYARPAMRLSSLMGIRVVYVMTHDSIGLGEDGPTHQPVEHLAAL
RAIPNHNVFRPADAVETAECWQLALHSRKTPSTLALTRQNLPTVRTEHREENLCAFGAYELAAASSDAKVTIFATGSEVE
IALKARDLLEGKGIATRVVSVPCFELFEQQSDTYKEATIGDAPVKLAIEAAISLGWERFIGENGIFIGMKGFGASGEIND
LYKHFGITAEHAVEAAEKKLNAA

Sequences:

>Translated_663_residues
MTNTDKQNQMANAIRFLSMDAVEKANSGHPGLPMGAADIATTLYTRFLSHDPKNPHWPDRDRFVLSAGHGSMLLYSLLYL
SGYEDITIDEIKKFRQLGSRTAGHPEYGHAAGIETTTGPLGQGIANAVGMAISERILNAQFGDSLVNHYTYALVGDGCLM
EGISQEAIALAGHLKLNKLIVLWDDNNISIDGPITLSDNTDQPARFAASGWNTMAVDGHDQDAIAKAIELARVSDRPTLI
ACKTTIGFGAPNKAGTNKVHGSPLGAEEIAATRKALGWSSEPFVVPAEVLDAWRVAGLNAAKKRLEWEKRLSAVEAETRA
EFERRMRGELPSGFDAAIVEYKKKLSADKPKVATRKSSEMALEVINGVVPETVGGSADLTGSNNTKTSQTKAVTPENYDG
RYIHYGIRELGMAAAMNGITLHGGLIPYSGTFLCFSDYARPAMRLSSLMGIRVVYVMTHDSIGLGEDGPTHQPVEHLAAL
RAIPNHNVFRPADAVETAECWQLALHSRKTPSTLALTRQNLPTVRTEHREENLCAFGAYELAAASSDAKVTIFATGSEVE
IALKARDLLEGKGIATRVVSVPCFELFEQQSDTYKEATIGDAPVKLAIEAAISLGWERFIGENGIFIGMKGFGASGEIND
LYKHFGITAEHAVEAAEKKLNAA
>Mature_662_residues
TNTDKQNQMANAIRFLSMDAVEKANSGHPGLPMGAADIATTLYTRFLSHDPKNPHWPDRDRFVLSAGHGSMLLYSLLYLS
GYEDITIDEIKKFRQLGSRTAGHPEYGHAAGIETTTGPLGQGIANAVGMAISERILNAQFGDSLVNHYTYALVGDGCLME
GISQEAIALAGHLKLNKLIVLWDDNNISIDGPITLSDNTDQPARFAASGWNTMAVDGHDQDAIAKAIELARVSDRPTLIA
CKTTIGFGAPNKAGTNKVHGSPLGAEEIAATRKALGWSSEPFVVPAEVLDAWRVAGLNAAKKRLEWEKRLSAVEAETRAE
FERRMRGELPSGFDAAIVEYKKKLSADKPKVATRKSSEMALEVINGVVPETVGGSADLTGSNNTKTSQTKAVTPENYDGR
YIHYGIRELGMAAAMNGITLHGGLIPYSGTFLCFSDYARPAMRLSSLMGIRVVYVMTHDSIGLGEDGPTHQPVEHLAALR
AIPNHNVFRPADAVETAECWQLALHSRKTPSTLALTRQNLPTVRTEHREENLCAFGAYELAAASSDAKVTIFATGSEVEI
ALKARDLLEGKGIATRVVSVPCFELFEQQSDTYKEATIGDAPVKLAIEAAISLGWERFIGENGIFIGMKGFGASGEINDL
YKHFGITAEHAVEAAEKKLNAA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=671, Percent_Identity=26.5275707898659, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI4507521, Length=671, Percent_Identity=26.5275707898659, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI133778974, Length=668, Percent_Identity=26.0479041916168, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI225637459, Length=672, Percent_Identity=22.6190476190476, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI225637461, Length=645, Percent_Identity=21.8604651162791, Blast_Score=122, Evalue=2e-27,
Organism=Homo sapiens, GI225637463, Length=567, Percent_Identity=23.4567901234568, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI48994911, Length=665, Percent_Identity=51.2781954887218, Blast_Score=667, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=663, Percent_Identity=48.4162895927602, Blast_Score=621, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI17539652, Length=571, Percent_Identity=27.3204903677758, Blast_Score=179, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6325331, Length=674, Percent_Identity=44.5103857566766, Blast_Score=529, Evalue=1e-151,
Organism=Saccharomyces cerevisiae, GI6319593, Length=676, Percent_Identity=43.7869822485207, Blast_Score=520, Evalue=1e-148,
Organism=Drosophila melanogaster, GI45551847, Length=669, Percent_Identity=26.3079222720478, Blast_Score=180, Evalue=4e-45,
Organism=Drosophila melanogaster, GI45550715, Length=669, Percent_Identity=26.3079222720478, Blast_Score=180, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24666278, Length=571, Percent_Identity=26.0945709281961, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24645119, Length=638, Percent_Identity=26.0188087774295, Blast_Score=162, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71519; Mature: 71388

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTDKQNQMANAIRFLSMDAVEKANSGHPGLPMGAADIATTLYTRFLSHDPKNPHWPDR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
DRFVLSAGHGSMLLYSLLYLSGYEDITIDEIKKFRQLGSRTAGHPEYGHAAGIETTTGPL
CCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
GQGIANAVGMAISERILNAQFGDSLVNHYTYALVGDGCLMEGISQEAIALAGHLKLNKLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHCCCHHHHHHHCCEEEEEEE
VLWDDNNISIDGPITLSDNTDQPARFAASGWNTMAVDGHDQDAIAKAIELARVSDRPTLI
EEECCCCEEECCCEEECCCCCCCCHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEE
ACKTTIGFGAPNKAGTNKVHGSPLGAEEIAATRKALGWSSEPFVVPAEVLDAWRVAGLNA
EEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECHHHHHHHHHCCCHH
AKKRLEWEKRLSAVEAETRAEFERRMRGELPSGFDAAIVEYKKKLSADKPKVATRKSSEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
ALEVINGVVPETVGGSADLTGSNNTKTSQTKAVTPENYDGRYIHYGIRELGMAAAMNGIT
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCEE
LHGGLIPYSGTFLCFSDYARPAMRLSSLMGIRVVYVMTHDSIGLGEDGPTHQPVEHLAAL
EECCCCCCCCEEEEEHHHCHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
RAIPNHNVFRPADAVETAECWQLALHSRKTPSTLALTRQNLPTVRTEHREENLCAFGAYE
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCEEEECCHH
LAAASSDAKVTIFATGSEVEIALKARDLLEGKGIATRVVSVPCFELFEQQSDTYKEATIG
HHCCCCCCEEEEEEECCCEEEEEEHHHHHCCCCCEEHEEHHHHHHHHHHCCCHHHHHCCC
DAPVKLAIEAAISLGWERFIGENGIFIGMKGFGASGEINDLYKHFGITAEHAVEAAEKKL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
NAA
CCC
>Mature Secondary Structure 
TNTDKQNQMANAIRFLSMDAVEKANSGHPGLPMGAADIATTLYTRFLSHDPKNPHWPDR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
DRFVLSAGHGSMLLYSLLYLSGYEDITIDEIKKFRQLGSRTAGHPEYGHAAGIETTTGPL
CCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCH
GQGIANAVGMAISERILNAQFGDSLVNHYTYALVGDGCLMEGISQEAIALAGHLKLNKLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHCCCHHHHHHHCCEEEEEEE
VLWDDNNISIDGPITLSDNTDQPARFAASGWNTMAVDGHDQDAIAKAIELARVSDRPTLI
EEECCCCEEECCCEEECCCCCCCCHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEE
ACKTTIGFGAPNKAGTNKVHGSPLGAEEIAATRKALGWSSEPFVVPAEVLDAWRVAGLNA
EEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECHHHHHHHHHCCCHH
AKKRLEWEKRLSAVEAETRAEFERRMRGELPSGFDAAIVEYKKKLSADKPKVATRKSSEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
ALEVINGVVPETVGGSADLTGSNNTKTSQTKAVTPENYDGRYIHYGIRELGMAAAMNGIT
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCEE
LHGGLIPYSGTFLCFSDYARPAMRLSSLMGIRVVYVMTHDSIGLGEDGPTHQPVEHLAAL
EECCCCCCCCEEEEEHHHCHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
RAIPNHNVFRPADAVETAECWQLALHSRKTPSTLALTRQNLPTVRTEHREENLCAFGAYE
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCCCCEEEECCHH
LAAASSDAKVTIFATGSEVEIALKARDLLEGKGIATRVVSVPCFELFEQQSDTYKEATIG
HHCCCCCCEEEEEEECCCEEEEEEHHHHHCCCCCEEHEEHHHHHHHHHHCCCHHHHHCCC
DAPVKLAIEAAISLGWERFIGENGIFIGMKGFGASGEINDLYKHFGITAEHAVEAAEKKL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
NAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]