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The map label for this gene is moaC [H]

Identifier: 225852641

GI number: 225852641

Start: 1139427

End: 1139924

Strand: Direct

Name: moaC [H]

Synonym: BMEA_A1186

Alternate gene names: 225852641

Gene position: 1139427-1139924 (Clockwise)

Preceding gene: 225852640

Following gene: 225852642

Centisome position: 53.6

GC content: 60.64

Gene sequence:

>498_bases
ATGAGCGGCAAACTCACCCATATCGACCAGACCGGCGCGGCAAACATGGTGGATGTCGGCAGCAAGGACGAAACCGAGCG
GCAGGCGGTCGCCGAAGGTGCGGTCAGGATGAAACCCGAAACGCTGGCCCTCATTCTCGAAGGCAATGCGGCCAAGGGCG
ATGTCATCGGCACGGCGAGGCTTGCGGGCATCATGGCAGCCAAGAGGACTTCCGATCTGATTCCGCTGTGCCATCCATTG
ATGTTGACAAAGGTGGCCGTGGAGATCGAGCCGGACGAGAACCTGCCCGGCCTGCGCGTGCGCGCACTAGCCCGATTGAA
AGGCCGGACAGGCGTGGAGATGGAGGCGCTGACTGCCGCATCCGTTACCTGCCTTACCATATACGACATGGCCAAGGCTG
TGGATCGCCACATGGAAATCGGCAGCATCCGCGTGATCGAAAAAAGCGGCGGGAAATCAGGCGACTGGGCTGTTTCTGAC
CCCGCTTCGATGCGTTAA

Upstream 100 bases:

>100_bases
AAAAGTCCGGCATCGGCACTTTTCTGATAGGCGAAAGCCTTATGCGACAACATGACGTTGCGGCAGCCACCCGCGCGCTT
TTGACGGGTGCGGAAAAGCT

Downstream 100 bases:

>100_bases
AAATACGATAAAACAAATGGTTAGAGTGGATCCGGCAATTCTGCTAAAACAGGAACCGCTCTAACGGGTCAAACAATTCA
GTTCGAGAGGAAACCATGCC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSGKLTHIDQTGAANMVDVGSKDETERQAVAEGAVRMKPETLALILEGNAAKGDVIGTARLAGIMAAKRTSDLIPLCHPL
MLTKVAVEIEPDENLPGLRVRALARLKGRTGVEMEALTAASVTCLTIYDMAKAVDRHMEIGSIRVIEKSGGKSGDWAVSD
PASMR

Sequences:

>Translated_165_residues
MSGKLTHIDQTGAANMVDVGSKDETERQAVAEGAVRMKPETLALILEGNAAKGDVIGTARLAGIMAAKRTSDLIPLCHPL
MLTKVAVEIEPDENLPGLRVRALARLKGRTGVEMEALTAASVTCLTIYDMAKAVDRHMEIGSIRVIEKSGGKSGDWAVSD
PASMR
>Mature_164_residues
SGKLTHIDQTGAANMVDVGSKDETERQAVAEGAVRMKPETLALILEGNAAKGDVIGTARLAGIMAAKRTSDLIPLCHPLM
LTKVAVEIEPDENLPGLRVRALARLKGRTGVEMEALTAASVTCLTIYDMAKAVDRHMEIGSIRVIEKSGGKSGDWAVSDP
ASMR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=60.6451612903226, Blast_Score=185, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.2953020134228, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28574490, Length=160, Percent_Identity=47.5, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI28574492, Length=146, Percent_Identity=47.945205479452, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17481; Mature: 17349

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKLTHIDQTGAANMVDVGSKDETERQAVAEGAVRMKPETLALILEGNAAKGDVIGTAR
CCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCCEEECCCEEEEEEECCCCCCCEEHHHH
LAGIMAAKRTSDLIPLCHPLMLTKVAVEIEPDENLPGLRVRALARLKGRTGVEMEALTAA
HHHHHHHHCCCCCCHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
SVTCLTIYDMAKAVDRHMEIGSIRVIEKSGGKSGDWAVSDPASMR
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
SGKLTHIDQTGAANMVDVGSKDETERQAVAEGAVRMKPETLALILEGNAAKGDVIGTAR
CCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCCEEECCCEEEEEEECCCCCCCEEHHHH
LAGIMAAKRTSDLIPLCHPLMLTKVAVEIEPDENLPGLRVRALARLKGRTGVEMEALTAA
HHHHHHHHCCCCCCHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
SVTCLTIYDMAKAVDRHMEIGSIRVIEKSGGKSGDWAVSDPASMR
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA