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The map label for this gene is thrB [H]

Identifier: 225852012

GI number: 225852012

Start: 494467

End: 495447

Strand: Direct

Name: thrB [H]

Synonym: BMEA_A0512

Alternate gene names: 225852012

Gene position: 494467-495447 (Clockwise)

Preceding gene: 225852011

Following gene: 225852013

Centisome position: 23.26

GC content: 58.61

Gene sequence:

>981_bases
ATGGCCGTCTATACGGATATTAACGAGATCGAGCTTGGCGCATTCCTGCGGCATTACGATATCGGCACGCTGACCTCCTA
TAAGGGGATCGCGGAAGGTGTGGAGAATTCCAACTATCTTCTGCATACGAGCTCCGGCTCCTTCATTCTGACGCTTTATG
AAAAGCGCACCAATCGTGAAGATCTGCCGTTTTTCCTCGGCCTTATGCAGCATCTGGCCAAGCGGGGGCTGGAATGCCCG
CAGCCGGTGGTGCGCAATGATGGCGCAATGATCGGCCAATTGGCCGGCCGCCCGGCGGCTATCGTCACTTTTCTCGAAGG
CATGTGGATGCGCAGGCCAACCGTCGCCCATTGCGAGGCGGTGGGCGAGGGGCTGGCGCATATGCATCTGGCGGGTGCGG
ATTTCCCCATGCGCCGCCGCAACGGGCTGACGCTGCCCGATTGGCGCCCGCTGTGGAACCTCTCGCGTAAATGCGCCGAT
ACGGTCGAGCGGGGATTGGTCGCCGAAACCGAGGCTGATCTCGATTTTCTCGAAAAGAACTGGCCTGCCGATCTGCCGCA
AGGCGTGATCCATGCCGATCTTTTTCCGGATAATGCCTTTTTTCTGGGCGACAGGCTTTCCGGCTTCATCGACTTTTATT
TCGCCTGCACGGATATTCTGGCCTATGACGTCGCCGTCTGCCTGAATGCCTGGTGTTTTGAAAAGGATTTTTCCTATAAC
CGCACCAAGGGCGCAGCCCTTCTGCGTGGTTACACTTCCGTGCGCCCGCTCTCGGAGGCCGAAGCCAATGCCTTGCTGGT
TCTGGCGCGCGGGGCTGCGGTTCGCTTCATGCTGACGCGGCTTTACGACTGGCTCACCGTGCCAGCCGGAAGCTTCGTGG
TGAAGAAAGACCCGATGGAATATGTGCGCCGGATGCGCTTTCACCGCCAGATCGAATCCGCTGCCGAATATGGCCTTGAA
ATGCAGGGAGTTGCGGCGTGA

Upstream 100 bases:

>100_bases
AAATCCGCGATGTGGAATTGACGGTGAAGGATATGGCATTCGTCAATGGCGAGCACCGCGTGGTCGGCATTTCCAAACTT
ATGCAGGGGAAGTAAGGGAC

Downstream 100 bases:

>100_bases
AGCGCATCGAGGCCTATACGGACGGGGCCTGTTCCGGCAATCCCGGTCCCGGCGGCTGGGGTGCATTGCTGCGGTGGAAC
GGCAATGAAAAGGAACTGAA

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNREDLPFFLGLMQHLAKRGLECP
QPVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEAVGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCAD
TVERGLVAETEADLDFLEKNWPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYN
RTKGAALLRGYTSVRPLSEAEANALLVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPMEYVRRMRFHRQIESAAEYGLE
MQGVAA

Sequences:

>Translated_326_residues
MAVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNREDLPFFLGLMQHLAKRGLECP
QPVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEAVGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCAD
TVERGLVAETEADLDFLEKNWPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYN
RTKGAALLRGYTSVRPLSEAEANALLVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPMEYVRRMRFHRQIESAAEYGLE
MQGVAA
>Mature_325_residues
AVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNREDLPFFLGLMQHLAKRGLECPQ
PVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEAVGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCADT
VERGLVAETEADLDFLEKNWPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYNR
TKGAALLRGYTSVRPLSEAEANALLVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPMEYVRRMRFHRQIESAAEYGLEM
QGVAA

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 36644; Mature: 36513

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNRE
CCEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCC
DLPFFLGLMQHLAKRGLECPQPVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEA
CCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHH
VGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCADTVERGLVAETEADLDFLEKN
HHCCHHHEEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
WPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYN
CCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RTKGAALLRGYTSVRPLSEAEANALLVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPME
CCCHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEECCHHH
YVRRMRFHRQIESAAEYGLEMQGVAA
HHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AVYTDINEIELGAFLRHYDIGTLTSYKGIAEGVENSNYLLHTSSGSFILTLYEKRTNRE
CEECCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCC
DLPFFLGLMQHLAKRGLECPQPVVRNDGAMIGQLAGRPAAIVTFLEGMWMRRPTVAHCEA
CCHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHH
VGEGLAHMHLAGADFPMRRRNGLTLPDWRPLWNLSRKCADTVERGLVAETEADLDFLEKN
HHCCHHHEEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
WPADLPQGVIHADLFPDNAFFLGDRLSGFIDFYFACTDILAYDVAVCLNAWCFEKDFSYN
CCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RTKGAALLRGYTSVRPLSEAEANALLVLARGAAVRFMLTRLYDWLTVPAGSFVVKKDPME
CCCHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEECCHHH
YVRRMRFHRQIESAAEYGLEMQGVAA
HHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA