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The map label for this gene is rodA [H]

Identifier: 225630961

GI number: 225630961

Start: 1370822

End: 1371925

Strand: Direct

Name: rodA [H]

Synonym: WRi_012830

Alternate gene names: 225630961

Gene position: 1370822-1371925 (Clockwise)

Preceding gene: 225630960

Following gene: 225630962

Centisome position: 94.81

GC content: 36.23

Gene sequence:

>1104_bases
GTGGATAGGCTGAAGAAGATTCATTGGTTATTAGTCATTAACGTGATAGCGCTGTTTTGCGTTGGCATTGTTGTTCAATA
CTCTTCTGCTGGAGGAAAGTGGGTGCCATTTGCGATTCACCAACTGATCATATTCTCCTTCTTTTTCCTACTCGCTATAG
CTATGTCATTCATAGAGCTAGATTTTTATTTGAAGTACGCCTACTTTTTTTATATAGCAGCAGCGATTTCACTATTAGCA
GTAAATTTTTTTGGCTCACACATAATGGGTGCAACAAGGTGGATAAGAATTGGATCAATTAGTTTGCAACCATCAGAATT
TGCAAAAGTAGGCTTAATACTTGCGCTTGCTCGCTATTTTGATAAGCAGAGTGTGTATAAAATGATGGAATTTAAAAGAT
TGCTTAAGGCACTTATAATTATTTTCTTACCCGTGTTCTTGGTGTTAAAGCAACCTAATTTAGGCACAGCTATGATAATG
TTATTTATAGGGATATCAATTATATTCACAACAATAATAAAAAGATCTCATTCAGTAATATGTGGAACTCTTGGCATTTT
TGCAGTACCGGCTATTTGGCCTTTTTTACGTCCTTATCACAAGCAAAGGATATTGTCATTTTTGGATTCATCAGTGGATC
CACTTGGAATAGGTTATAATGCGCAGCAATCTCAAATAGCTATTGGTTCAGGAGGTTTGTTTGGTAAGGGCTTTGTTAAC
GGAAGTCAAACTCAACTTGGATTTTTGCCGGAGAAACGTACAGATTTTGCTTTTGCAGTGCTGAGTGAGGAATGGGGATT
TTTAGGTAGCATGACTTTAATTTTACTCTATACTACATTGCTTGCTATAATGCTCTCTATTGCTTATAGGTCAAAAAATT
ATTTTTCTAAGTCGGTATCTATCGGCATTTTTGCCTTTTTTAGTGCTCATTTCTTTATAAACATCGGAATGACAATGGGC
CTCTTACCTGTAATAGGCGACCCATTGCCATTTCTGTCCTATGGAGGAAGTACAACTGCTGCAAGCTTAATATGTATAGG
GCTATTGCTAGCAATAAAAGCAGATGAACAACAAAATACTTGTATTTTACCTATGCTAAAGTAA

Upstream 100 bases:

>100_bases
TATATAGCACTCCAATTCGGTTAGTAGTTGAGAAGTTGGTTTTTTGATTTTTATCTTTGTTTCATATTTTACTATACTTT
AAGGTTATAAGGTCTTTATT

Downstream 100 bases:

>100_bases
AATTTAACTTTACTTAATAGTTTTTATGCTAGATGAAATGCGTGAGGAGTGTGGGGTATTTGGCATAAGTTGCAACCAAA
GTGCTGCTTTTAACTCTATA

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MDRLKKIHWLLVINVIALFCVGIVVQYSSAGGKWVPFAIHQLIIFSFFFLLAIAMSFIELDFYLKYAYFFYIAAAISLLA
VNFFGSHIMGATRWIRIGSISLQPSEFAKVGLILALARYFDKQSVYKMMEFKRLLKALIIIFLPVFLVLKQPNLGTAMIM
LFIGISIIFTTIIKRSHSVICGTLGIFAVPAIWPFLRPYHKQRILSFLDSSVDPLGIGYNAQQSQIAIGSGGLFGKGFVN
GSQTQLGFLPEKRTDFAFAVLSEEWGFLGSMTLILLYTTLLAIMLSIAYRSKNYFSKSVSIGIFAFFSAHFFINIGMTMG
LLPVIGDPLPFLSYGGSTTAASLICIGLLLAIKADEQQNTCILPMLK

Sequences:

>Translated_367_residues
MDRLKKIHWLLVINVIALFCVGIVVQYSSAGGKWVPFAIHQLIIFSFFFLLAIAMSFIELDFYLKYAYFFYIAAAISLLA
VNFFGSHIMGATRWIRIGSISLQPSEFAKVGLILALARYFDKQSVYKMMEFKRLLKALIIIFLPVFLVLKQPNLGTAMIM
LFIGISIIFTTIIKRSHSVICGTLGIFAVPAIWPFLRPYHKQRILSFLDSSVDPLGIGYNAQQSQIAIGSGGLFGKGFVN
GSQTQLGFLPEKRTDFAFAVLSEEWGFLGSMTLILLYTTLLAIMLSIAYRSKNYFSKSVSIGIFAFFSAHFFINIGMTMG
LLPVIGDPLPFLSYGGSTTAASLICIGLLLAIKADEQQNTCILPMLK
>Mature_367_residues
MDRLKKIHWLLVINVIALFCVGIVVQYSSAGGKWVPFAIHQLIIFSFFFLLAIAMSFIELDFYLKYAYFFYIAAAISLLA
VNFFGSHIMGATRWIRIGSISLQPSEFAKVGLILALARYFDKQSVYKMMEFKRLLKALIIIFLPVFLVLKQPNLGTAMIM
LFIGISIIFTTIIKRSHSVICGTLGIFAVPAIWPFLRPYHKQRILSFLDSSVDPLGIGYNAQQSQIAIGSGGLFGKGFVN
GSQTQLGFLPEKRTDFAFAVLSEEWGFLGSMTLILLYTTLLAIMLSIAYRSKNYFSKSVSIGIFAFFSAHFFINIGMTMG
LLPVIGDPLPFLSYGGSTTAASLICIGLLLAIKADEQQNTCILPMLK

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=310, Percent_Identity=38.3870967741935, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1786277, Length=324, Percent_Identity=30.5555555555556, Blast_Score=145, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40802; Mature: 40802

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLKKIHWLLVINVIALFCVGIVVQYSSAGGKWVPFAIHQLIIFSFFFLLAIAMSFIEL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DFYLKYAYFFYIAAAISLLAVNFFGSHIMGATRWIRIGSISLQPSEFAKVGLILALARYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECEECCHHHHHHHHHHHHHHHHH
DKQSVYKMMEFKRLLKALIIIFLPVFLVLKQPNLGTAMIMLFIGISIIFTTIIKRSHSVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
CGTLGIFAVPAIWPFLRPYHKQRILSFLDSSVDPLGIGYNAQQSQIAIGSGGLFGKGFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
GSQTQLGFLPEKRTDFAFAVLSEEWGFLGSMTLILLYTTLLAIMLSIAYRSKNYFSKSVS
CCCCEECCCCCCCCCHHHEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIFAFFSAHFFINIGMTMGLLPVIGDPLPFLSYGGSTTAASLICIGLLLAIKADEQQNT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
CILPMLK
EECCCCC
>Mature Secondary Structure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EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]