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The map label for this gene is nuoN [H]

Identifier: 225630960

GI number: 225630960

Start: 1369302

End: 1370768

Strand: Direct

Name: nuoN [H]

Synonym: WRi_012820

Alternate gene names: 225630960

Gene position: 1369302-1370768 (Clockwise)

Preceding gene: 225630956

Following gene: 225630961

Centisome position: 94.7

GC content: 34.42

Gene sequence:

>1467_bases
ATGCAATTACCAATCTTACAAGTTATTATCCCAATAATTGCATCAATGTTTTGCTTTCTTGCCAAGAAACACAAGGTATC
TTGGTTTATTTCTTTTATTGCAACAACAATCACTCTTATCATTTCATCAATACTACTCATAAAAACATATAGAGGCGAGA
TTATAACTTATCACCTTGGAAATTGGGCTCCTCCGTATGGAATAGAGTTAAGAATCGACGTGTTAAATTCCTTAATTCTA
ACCCTAGTGAATTTTATAGCGCTGATTAGTGTGCTTTATAGCTTTTATATTAACGAAAAAGAGATTAGCAAAAACAAAAT
CACTGGTTTTTACTCTCTATTTCTACTGTGCTTAAGCGGACTGCTCGGGATTCTAGTAACAAACGACATATTTAACCTTT
ACGTTTTCTTGGAAATTTCATCTCTTTCTTCTTATGTATTAGTTTCAATGGGAAGGGATAAAAAAGCCTTAGTTGCAGCA
TTTGAATATCTAATTAGTGGAACAATAGGTGCAACATTTTATTTATTTGGCATCGGGCTCTTGTATTCAATGACTGGAAC
GCTCAATATGTCTGACATGGCTGAAAGAATAGTTCCATTATACGATAACAACATCATAAAACTTGGCACGTTGTTCATTT
TTGTTGGTCTCTCAATCAAAATGGCACTGTTTCCATTAAGCAGGTGGCTGGTTAATGCATATAGTGAGGCGCCAAGTTTC
ATTAGCATATTCTTTTCAGGCACAGTGACAAAAGTGATGATATATGTTTTCATCAGAATCTTTTATACTGTTTTTCATCA
AAATTTTTTCTTGTTTAAGCCGCTGTTGGACAATGTGATAATTATCCTCGCACTTTGCGCTATTGTATTTGGGTCGATAT
TTGCAATAACCGCAAAAGACATAAAAAGACTGCTTGCTCACTCTAGTATTAGCCAAATTGGTTATATAATTTTAGCACTG
AGTTTTAACTCAAAAACAGGTGTATTTGCAGCAATTCTTCACATAGTAAACCACAGCATAATAAAAACATCTTTATTCAT
GGCTGCAGGATGTATTTCTTACAAATTTGATACAACAAAAATAGAGAATTTATCGGGACTCAAGAAATCAATGCCTTATA
CAGCACTTGCGTTCACTCTACTCAGTTTAGCATTAATCGGTGTGCCTTTAACAAATGGCTTTGTAAGCAAGTGGTATATA
ATGAAAGCAATTATTGAATCTCATGCGTGGATTTCCCTTGTAACATTTGCTGCTGGCTCTTTCCTTGCATTGATATATAT
GTGGAAGATGGTAGAGAAAATGTATTTTGAAAATGATGCAACGTCACGCACTGGAATGACACTAGGCAAAATTAATGATG
TGCCATTTCCTATGCTTTTCTGTCTATTGTTTATGGCAGCTTTAACAGTAGTAACTGGAATATATAGCACTCCAATTCGG
TTAGTAGTTGAGAAGTTGGTTTTTTGA

Upstream 100 bases:

>100_bases
TAGGCGTTTTATTGCATTACAAATTTTAGATAACATAAGGGTATTAAAACAAAAAGTATTATATATACTAATACTTTAAC
GATATATTAACAACAATTTA

Downstream 100 bases:

>100_bases
TTTTTATCTTTGTTTCATATTTTACTATACTTTAAGGTTATAAGGTCTTTATTGTGGATAGGCTGAAGAAGATTCATTGG
TTATTAGTCATTAACGTGAT

Product: putative monovalent cation/H+ antiporter subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MQLPILQVIIPIIASMFCFLAKKHKVSWFISFIATTITLIISSILLIKTYRGEIITYHLGNWAPPYGIELRIDVLNSLIL
TLVNFIALISVLYSFYINEKEISKNKITGFYSLFLLCLSGLLGILVTNDIFNLYVFLEISSLSSYVLVSMGRDKKALVAA
FEYLISGTIGATFYLFGIGLLYSMTGTLNMSDMAERIVPLYDNNIIKLGTLFIFVGLSIKMALFPLSRWLVNAYSEAPSF
ISIFFSGTVTKVMIYVFIRIFYTVFHQNFFLFKPLLDNVIIILALCAIVFGSIFAITAKDIKRLLAHSSISQIGYIILAL
SFNSKTGVFAAILHIVNHSIIKTSLFMAAGCISYKFDTTKIENLSGLKKSMPYTALAFTLLSLALIGVPLTNGFVSKWYI
MKAIIESHAWISLVTFAAGSFLALIYMWKMVEKMYFENDATSRTGMTLGKINDVPFPMLFCLLFMAALTVVTGIYSTPIR
LVVEKLVF

Sequences:

>Translated_488_residues
MQLPILQVIIPIIASMFCFLAKKHKVSWFISFIATTITLIISSILLIKTYRGEIITYHLGNWAPPYGIELRIDVLNSLIL
TLVNFIALISVLYSFYINEKEISKNKITGFYSLFLLCLSGLLGILVTNDIFNLYVFLEISSLSSYVLVSMGRDKKALVAA
FEYLISGTIGATFYLFGIGLLYSMTGTLNMSDMAERIVPLYDNNIIKLGTLFIFVGLSIKMALFPLSRWLVNAYSEAPSF
ISIFFSGTVTKVMIYVFIRIFYTVFHQNFFLFKPLLDNVIIILALCAIVFGSIFAITAKDIKRLLAHSSISQIGYIILAL
SFNSKTGVFAAILHIVNHSIIKTSLFMAAGCISYKFDTTKIENLSGLKKSMPYTALAFTLLSLALIGVPLTNGFVSKWYI
MKAIIESHAWISLVTFAAGSFLALIYMWKMVEKMYFENDATSRTGMTLGKINDVPFPMLFCLLFMAALTVVTGIYSTPIR
LVVEKLVF
>Mature_488_residues
MQLPILQVIIPIIASMFCFLAKKHKVSWFISFIATTITLIISSILLIKTYRGEIITYHLGNWAPPYGIELRIDVLNSLIL
TLVNFIALISVLYSFYINEKEISKNKITGFYSLFLLCLSGLLGILVTNDIFNLYVFLEISSLSSYVLVSMGRDKKALVAA
FEYLISGTIGATFYLFGIGLLYSMTGTLNMSDMAERIVPLYDNNIIKLGTLFIFVGLSIKMALFPLSRWLVNAYSEAPSF
ISIFFSGTVTKVMIYVFIRIFYTVFHQNFFLFKPLLDNVIIILALCAIVFGSIFAITAKDIKRLLAHSSISQIGYIILAL
SFNSKTGVFAAILHIVNHSIIKTSLFMAAGCISYKFDTTKIENLSGLKKSMPYTALAFTLLSLALIGVPLTNGFVSKWYI
MKAIIESHAWISLVTFAAGSFLALIYMWKMVEKMYFENDATSRTGMTLGKINDVPFPMLFCLLFMAALTVVTGIYSTPIR
LVVEKLVF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=330, Percent_Identity=27.2727272727273, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1788831, Length=352, Percent_Identity=31.25, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1788827, Length=443, Percent_Identity=27.765237020316, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788829, Length=412, Percent_Identity=28.6407766990291, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1788613, Length=505, Percent_Identity=25.5445544554455, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693160, Length=438, Percent_Identity=26.7123287671233, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788614, Length=371, Percent_Identity=26.9541778975741, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI2367154, Length=349, Percent_Identity=23.7822349570201, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 54633; Mature: 54633

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPILQVIIPIIASMFCFLAKKHKVSWFISFIATTITLIISSILLIKTYRGEIITYHLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
NWAPPYGIELRIDVLNSLILTLVNFIALISVLYSFYINEKEISKNKITGFYSLFLLCLSG
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LLGILVTNDIFNLYVFLEISSLSSYVLVSMGRDKKALVAAFEYLISGTIGATFYLFGIGL
HHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYSMTGTLNMSDMAERIVPLYDNNIIKLGTLFIFVGLSIKMALFPLSRWLVNAYSEAPSF
HHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ISIFFSGTVTKVMIYVFIRIFYTVFHQNFFLFKPLLDNVIIILALCAIVFGSIFAITAKD
EEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKRLLAHSSISQIGYIILALSFNSKTGVFAAILHIVNHSIIKTSLFMAAGCISYKFDTTK
HHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCH
IENLSGLKKSMPYTALAFTLLSLALIGVPLTNGFVSKWYIMKAIIESHAWISLVTFAAGS
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FLALIYMWKMVEKMYFENDATSRTGMTLGKINDVPFPMLFCLLFMAALTVVTGIYSTPIR
HHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
LVVEKLVF
HHHHHHCC
>Mature Secondary Structure
MQLPILQVIIPIIASMFCFLAKKHKVSWFISFIATTITLIISSILLIKTYRGEIITYHLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
NWAPPYGIELRIDVLNSLILTLVNFIALISVLYSFYINEKEISKNKITGFYSLFLLCLSG
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LLGILVTNDIFNLYVFLEISSLSSYVLVSMGRDKKALVAAFEYLISGTIGATFYLFGIGL
HHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYSMTGTLNMSDMAERIVPLYDNNIIKLGTLFIFVGLSIKMALFPLSRWLVNAYSEAPSF
HHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ISIFFSGTVTKVMIYVFIRIFYTVFHQNFFLFKPLLDNVIIILALCAIVFGSIFAITAKD
EEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKRLLAHSSISQIGYIILALSFNSKTGVFAAILHIVNHSIIKTSLFMAAGCISYKFDTTK
HHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCH
IENLSGLKKSMPYTALAFTLLSLALIGVPLTNGFVSKWYIMKAIIESHAWISLVTFAAGS
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FLALIYMWKMVEKMYFENDATSRTGMTLGKINDVPFPMLFCLLFMAALTVVTGIYSTPIR
HHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
LVVEKLVF
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA