Click here to switch to the map view.

The map label for this gene is ctrA [H]

Identifier: 225630493

GI number: 225630493

Start: 807159

End: 807929

Strand: Reverse

Name: ctrA [H]

Synonym: WRi_007440

Alternate gene names: 225630493

Gene position: 807929-807159 (Counterclockwise)

Preceding gene: 225630498

Following gene: 225630491

Centisome position: 55.88

GC content: 35.15

Gene sequence:

>771_bases
ATGCGTATATTATTAATTGAAGATGATCAAGTAAGTGCAAAGACTGTGGTTAACGCCTTAACTTCTGATGGACATTTCTG
TGACGTTGTTACTTCTGCACAAGATTATAACAATAATATGGTTTCCTCAAACGGAGATTACTATGACCTAGTTATTTTAG
ATATACACTTGCCTGGTGATATTGACGGATATGATATATTGCTAAGACTAAGAAGTGCAAAAATCAAAGTTCCTGTCTTA
ATACTTTCATGTATATCCGCTGTCAATCACAAAGCTAAAGGACTCGGGTATGGTGCCGATGATTACTTAACCAAACCATT
TCATAAAAGTGAGTTATTAGCTCGAATTAAGGCCATAGTGCGTCGTACTAAAGGCCATCCTGAATCGGTGATAAAGATTG
GTAATATAAATATCAATTTTGATCACAGGATTGTTGAGGTGAAAGGTAAAACGGTTCACCTTACTAATAAAGAGTATTCT
ATGATAGAATTGCTAGCACTGCGTAAAGGAACAGTATTAACAAAAGAAATGTTCTTAAATCATCTTTACAATGGCTTAGA
TGAACCTTCAGATAACAAGATAGTTGATGTTTTTATGTGCAAATTACGTAAGAAACTTGAAAGTGCAAATGATGGAAAAA
GCCACATAGAAACCGTTTGGGGCAGAGGGTATGTTCTGAAAGAGTATATTGATGATGATGAATATTCTAATGTTAATGTA
GGCGAAAGTAGTGATGGCTATCAAGCAGAACAAGTGAAGGACAACGCATGA

Upstream 100 bases:

>100_bases
ATAAGTGTAATTTTGATCATTTGTTAATAAAAATTTGATTTATTACTTTCCTTAGTTATATATATTACTAAAATTATAAA
TTATTTATGGGGTGTAAAAT

Downstream 100 bases:

>100_bases
AATGCCTACACATTTAAATATAGCATGGCTTATATCGCACGTATCATGTGAACGCCTAGGTGAAATATAAGCCGAGTTCT
GTTTATGTAGCTATTTATCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRILLIEDDQVSAKTVVNALTSDGHFCDVVTSAQDYNNNMVSSNGDYYDLVILDIHLPGDIDGYDILLRLRSAKIKVPVL
ILSCISAVNHKAKGLGYGADDYLTKPFHKSELLARIKAIVRRTKGHPESVIKIGNININFDHRIVEVKGKTVHLTNKEYS
MIELLALRKGTVLTKEMFLNHLYNGLDEPSDNKIVDVFMCKLRKKLESANDGKSHIETVWGRGYVLKEYIDDDEYSNVNV
GESSDGYQAEQVKDNA

Sequences:

>Translated_256_residues
MRILLIEDDQVSAKTVVNALTSDGHFCDVVTSAQDYNNNMVSSNGDYYDLVILDIHLPGDIDGYDILLRLRSAKIKVPVL
ILSCISAVNHKAKGLGYGADDYLTKPFHKSELLARIKAIVRRTKGHPESVIKIGNININFDHRIVEVKGKTVHLTNKEYS
MIELLALRKGTVLTKEMFLNHLYNGLDEPSDNKIVDVFMCKLRKKLESANDGKSHIETVWGRGYVLKEYIDDDEYSNVNV
GESSDGYQAEQVKDNA
>Mature_256_residues
MRILLIEDDQVSAKTVVNALTSDGHFCDVVTSAQDYNNNMVSSNGDYYDLVILDIHLPGDIDGYDILLRLRSAKIKVPVL
ILSCISAVNHKAKGLGYGADDYLTKPFHKSELLARIKAIVRRTKGHPESVIKIGNININFDHRIVEVKGKTVHLTNKEYS
MIELLALRKGTVLTKEMFLNHLYNGLDEPSDNKIVDVFMCKLRKKLESANDGKSHIETVWGRGYVLKEYIDDDEYSNVNV
GESSDGYQAEQVKDNA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=39.3805309734513, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.6491228070175, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=38.1578947368421, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=36.1607142857143, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=32.1888412017167, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=30.6034482758621, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=32.1428571428571, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=31.4159292035398, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=29.9559471365639, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=29.7777777777778, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367329, Length=175, Percent_Identity=32, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=28.1385281385281, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=28.0172413793103, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI145693140, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28743; Mature: 28743

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDQVSAKTVVNALTSDGHFCDVVTSAQDYNNNMVSSNGDYYDLVILDIHLPGD
CEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCHHCCCCEECCCCCEEEEEEEEEECCCC
IDGYDILLRLRSAKIKVPVLILSCISAVNHKAKGLGYGADDYLTKPFHKSELLARIKAIV
CCHHHEEEEECCCCCCHHHHHHHHHHHHCHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHH
RRTKGHPESVIKIGNININFDHRIVEVKGKTVHLTNKEYSMIELLALRKGTVLTKEMFLN
HHCCCCCCCEEEEECEEEEECEEEEEEECCEEEEECCCHHHHHHHHHHCCCHHHHHHHHH
HLYNGLDEPSDNKIVDVFMCKLRKKLESANDGKSHIETVWGRGYVLKEYIDDDEYSNVNV
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCC
GESSDGYQAEQVKDNA
CCCCCCCCHHHCCCCC
>Mature Secondary Structure
MRILLIEDDQVSAKTVVNALTSDGHFCDVVTSAQDYNNNMVSSNGDYYDLVILDIHLPGD
CEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCHHCCCCEECCCCCEEEEEEEEEECCCC
IDGYDILLRLRSAKIKVPVLILSCISAVNHKAKGLGYGADDYLTKPFHKSELLARIKAIV
CCHHHEEEEECCCCCCHHHHHHHHHHHHCHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHH
RRTKGHPESVIKIGNININFDHRIVEVKGKTVHLTNKEYSMIELLALRKGTVLTKEMFLN
HHCCCCCCCEEEEECEEEEECEEEEEEECCEEEEECCCHHHHHHHHHHCCCHHHHHHHHH
HLYNGLDEPSDNKIVDVFMCKLRKKLESANDGKSHIETVWGRGYVLKEYIDDDEYSNVNV
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCC
GESSDGYQAEQVKDNA
CCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA