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The map label for this gene is sdhB [H]

Identifier: 225630498

GI number: 225630498

Start: 811692

End: 812480

Strand: Reverse

Name: sdhB [H]

Synonym: WRi_007490

Alternate gene names: 225630498

Gene position: 812480-811692 (Counterclockwise)

Preceding gene: 225630499

Following gene: 225630493

Centisome position: 56.19

GC content: 35.61

Gene sequence:

>789_bases
ATGGTTCAGTTTTCTTTGCCAAAGAATTCTAAAATTAATCAAAAGGGCAAAATTTATCCTATTCCTGCTAGAGCAAAAAA
CATCAGAAGATTTCAAATTTACCGTTGGTCTGCTGATGACGAGAAAAACCCTAGAATAGACACATTTTTTATTGATATGG
ATAGTTGTGGCCCTATGGTACTTGATGCATTAATAAAAATAAAGGATGAAATAGATTCGACTTTAACTTTCAGACGTTCT
TGTAGAGAAGGCATATGTGGATCTTGTGCCATGAATATTGACGGAACCAATACTCTTGCATGTACTAGATCTATACATGA
TATAAAAGGTGACGTAAAAATATATCCATTACCTCACATGTATGTAATAAAGGACCTAGTCTCGGATTTGAGCCAATTTT
ATGAGCAATACAAATCAATTAAACCTTGGTTACAAGCAGATAAGCCTGCCCTACCAAATAAAGAATACTCTCAATCTTCT
GAAGATAGAAAAAAATTAGATGGCTTGTCCGACTGTATATTATGTGCTTGCTGTTCGACTGGTTGCCCAAGCTACTGGTG
GAATAGTGATAAATTTTTAGGACCAGCAATACTATTACAAGCTTACAGATGGATTGCTGACAGCCGTGATAATAAGACAG
GTGAAAGACTTGATGTTTTAAACGACCCATTCAAGTTGTATCGTTGTCATGCAATAATGAATTGCACAAAAACTTGTCCT
AAAGGACTTAATCCAGCAAGAGCAATAGCGAAAGTAAAACAGCTCATGGTAGAGAGAGAAGGAGTTTAA

Upstream 100 bases:

>100_bases
TGTGTGCGATTTAAAAGGAATTTAATAAAAATATAGTAGATGATAATAAAATATGTTATCTACAAAGGGTTTTAGCTATA
AACAATAAAAGGTAAGTGAT

Downstream 100 bases:

>100_bases
GTATTATCTTTTGCATTCTTCGTAAGAGAACAGCAAACCTTCCGAAGCGTAGGGTATTGTTAATACCCTGAACGCTTTTC
CGTTTGTGAAGTGCATCGTA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MVQFSLPKNSKINQKGKIYPIPARAKNIRRFQIYRWSADDEKNPRIDTFFIDMDSCGPMVLDALIKIKDEIDSTLTFRRS
CREGICGSCAMNIDGTNTLACTRSIHDIKGDVKIYPLPHMYVIKDLVSDLSQFYEQYKSIKPWLQADKPALPNKEYSQSS
EDRKKLDGLSDCILCACCSTGCPSYWWNSDKFLGPAILLQAYRWIADSRDNKTGERLDVLNDPFKLYRCHAIMNCTKTCP
KGLNPARAIAKVKQLMVEREGV

Sequences:

>Translated_262_residues
MVQFSLPKNSKINQKGKIYPIPARAKNIRRFQIYRWSADDEKNPRIDTFFIDMDSCGPMVLDALIKIKDEIDSTLTFRRS
CREGICGSCAMNIDGTNTLACTRSIHDIKGDVKIYPLPHMYVIKDLVSDLSQFYEQYKSIKPWLQADKPALPNKEYSQSS
EDRKKLDGLSDCILCACCSTGCPSYWWNSDKFLGPAILLQAYRWIADSRDNKTGERLDVLNDPFKLYRCHAIMNCTKTCP
KGLNPARAIAKVKQLMVEREGV
>Mature_262_residues
MVQFSLPKNSKINQKGKIYPIPARAKNIRRFQIYRWSADDEKNPRIDTFFIDMDSCGPMVLDALIKIKDEIDSTLTFRRS
CREGICGSCAMNIDGTNTLACTRSIHDIKGDVKIYPLPHMYVIKDLVSDLSQFYEQYKSIKPWLQADKPALPNKEYSQSS
EDRKKLDGLSDCILCACCSTGCPSYWWNSDKFLGPAILLQAYRWIADSRDNKTGERLDVLNDPFKLYRCHAIMNCTKTCP
KGLNPARAIAKVKQLMVEREGV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=238, Percent_Identity=66.3865546218487, Blast_Score=336, Evalue=2e-92,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=51.9148936170213, Blast_Score=252, Evalue=2e-68,
Organism=Escherichia coli, GI1790596, Length=231, Percent_Identity=31.6017316017316, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17533915, Length=233, Percent_Identity=60.0858369098712, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6322987, Length=229, Percent_Identity=62.0087336244542, Blast_Score=309, Evalue=3e-85,
Organism=Drosophila melanogaster, GI17137106, Length=259, Percent_Identity=59.8455598455598, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI24643156, Length=240, Percent_Identity=62.9166666666667, Blast_Score=326, Evalue=1e-89,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29923; Mature: 29923

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQFSLPKNSKINQKGKIYPIPARAKNIRRFQIYRWSADDEKNPRIDTFFIDMDSCGPMV
CEEECCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCHHH
LDALIKIKDEIDSTLTFRRSCREGICGSCAMNIDGTNTLACTRSIHDIKGDVKIYPLPHM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCHH
YVIKDLVSDLSQFYEQYKSIKPWLQADKPALPNKEYSQSSEDRKKLDGLSDCILCACCST
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHCCHHHHHHHCCHHHHHHHHHHCC
GCPSYWWNSDKFLGPAILLQAYRWIADSRDNKTGERLDVLNDPFKLYRCHAIMNCTKTCP
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCC
KGLNPARAIAKVKQLMVEREGV
CCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQFSLPKNSKINQKGKIYPIPARAKNIRRFQIYRWSADDEKNPRIDTFFIDMDSCGPMV
CEEECCCCCCCCCCCCCEEECCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCCCHHH
LDALIKIKDEIDSTLTFRRSCREGICGSCAMNIDGTNTLACTRSIHDIKGDVKIYPLPHM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCHH
YVIKDLVSDLSQFYEQYKSIKPWLQADKPALPNKEYSQSSEDRKKLDGLSDCILCACCST
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHCCHHHHHHHCCHHHHHHHHHHCC
GCPSYWWNSDKFLGPAILLQAYRWIADSRDNKTGERLDVLNDPFKLYRCHAIMNCTKTCP
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCC
KGLNPARAIAKVKQLMVEREGV
CCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA