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The map label for this gene is yycG [H]

Identifier: 222526335

GI number: 222526335

Start: 3825709

End: 3826986

Strand: Direct

Name: yycG [H]

Synonym: Chy400_3101

Alternate gene names: 222526335

Gene position: 3825709-3826986 (Clockwise)

Preceding gene: 222526334

Following gene: 222526343

Centisome position: 72.61

GC content: 56.34

Gene sequence:

>1278_bases
ATGATGCTGCTCGAATGGATGCTGATGGTAGCGACGATTGCACTGGCGGTTGGGTTTATCGTCAGTATGTATCGCCGACA
TCAGAAGAGCCATTCATCATTGGTTGACCATCCCTCTCCGCCCGGTACTCAGGAACACTCCATGATCTCATCTGCCAGAT
CAGAAACGATAACGTCCGATTCGCATCTTGCGTTGTTAGCCATTCATCGTCAGCCGCTCTTTCTGGCGCTGGCAGCAGCG
ATTGATACCGGTGTGATTGTGATCAATACCGAACGTCGTATTGTCTTTCACAACGACACCGCGCTGCATCTCCTGGCTAC
TCAATCGCCGATGCAAGACAGCGGCCTGATTACACTGCTCCGCGATCATCAAGCCGATCAGTTAGCCTCTGATGTGCTTA
GCGATGGAGAACATCGTGAATTGACGATCCGTCCAATCGCAACCGGGCGGACATTACATTTGCACTACGTGCCATTGCGG
GAAGGGGGCGGAAAACCGGTTGGCGCTCTGATCACGATTCGCGACCTGACGCAAATCAGTATGCTTGAACGTGCGCGGCG
TGATCTGGTGGCGAATGTATCGCACGAGTTGCGCACGCCACTGGCTTCGCTTAAGTTGCTGGTGGAGACCGTACAATCAG
CACCACCCCCCGATATTGCCAGCCGTATGCTGGAGCAGATGGCGCAAGAGATTGATGCCGTCACGCAACTGGTTGACGAA
TTGCACGAGCTTTCCCGCCTTGAGTCGGGGCGGGTCTCGCTCAAGCTGGAACCGTTACCGGTCTGGCCGGTGATCGAACG
TGCCGTTGAGCGCATTCGACCCCAGGCTGATCGTAAACAACAAGTGATCTGCGTCGAGCCGGCGGCTGATTTGCCACTGG
CATTGATGGACGGTGATCGAATTGGTCAGGTATTGTTGAATCTGCTCCACAATGCGGTGAAGTTTACACCTGAAGGTGGA
ACCATCACGGTAGCGGCTGAGGTGCTGACCCTGCGTGATGATGAACAACCGTCACGGCCTGATCGTCCTCCGCATCCGGC
GGGGACGTGGTTACTGATCAGGGTCAGCGACACCGGCATCGGAATTCCCAATCGCGATATTCAACGCATCTTCGAGCGCT
TCTACAAAGTTGACCGGGCGCGCACCCGCCACGCTGGAGGTACCGGGTTGGGTCTGGCAATTGCCAAGCACCTGGTCGAG
GGCCACGGTGGCCGCATCTGGGCGAGCAGTCAGGAAGGACACGGCTCGACCTTCTGGTTTACGCTACCGGCAGCGTAG

Upstream 100 bases:

>100_bases
GAAGATAGAGCCAGACCCTGGCAAACCGGTTTATATCCAGACGGTGCGAGGGGTTGGGTATCGGTTTGAACCGCCATCTG
ATGATGCGTAAATTGCACCA

Downstream 100 bases:

>100_bases
AGTGGGTGCTATTGGGAGGGCAACGTCAGGGTTGTTCTGCATGGTATCTGCCGTGATCCTTACGCCGTACCCTTCAGCGC
TCTACTGTGGTGCACAAACA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MMLLEWMLMVATIALAVGFIVSMYRRHQKSHSSLVDHPSPPGTQEHSMISSARSETITSDSHLALLAIHRQPLFLALAAA
IDTGVIVINTERRIVFHNDTALHLLATQSPMQDSGLITLLRDHQADQLASDVLSDGEHRELTIRPIATGRTLHLHYVPLR
EGGGKPVGALITIRDLTQISMLERARRDLVANVSHELRTPLASLKLLVETVQSAPPPDIASRMLEQMAQEIDAVTQLVDE
LHELSRLESGRVSLKLEPLPVWPVIERAVERIRPQADRKQQVICVEPAADLPLALMDGDRIGQVLLNLLHNAVKFTPEGG
TITVAAEVLTLRDDEQPSRPDRPPHPAGTWLLIRVSDTGIGIPNRDIQRIFERFYKVDRARTRHAGGTGLGLAIAKHLVE
GHGGRIWASSQEGHGSTFWFTLPAA

Sequences:

>Translated_425_residues
MMLLEWMLMVATIALAVGFIVSMYRRHQKSHSSLVDHPSPPGTQEHSMISSARSETITSDSHLALLAIHRQPLFLALAAA
IDTGVIVINTERRIVFHNDTALHLLATQSPMQDSGLITLLRDHQADQLASDVLSDGEHRELTIRPIATGRTLHLHYVPLR
EGGGKPVGALITIRDLTQISMLERARRDLVANVSHELRTPLASLKLLVETVQSAPPPDIASRMLEQMAQEIDAVTQLVDE
LHELSRLESGRVSLKLEPLPVWPVIERAVERIRPQADRKQQVICVEPAADLPLALMDGDRIGQVLLNLLHNAVKFTPEGG
TITVAAEVLTLRDDEQPSRPDRPPHPAGTWLLIRVSDTGIGIPNRDIQRIFERFYKVDRARTRHAGGTGLGLAIAKHLVE
GHGGRIWASSQEGHGSTFWFTLPAA
>Mature_425_residues
MMLLEWMLMVATIALAVGFIVSMYRRHQKSHSSLVDHPSPPGTQEHSMISSARSETITSDSHLALLAIHRQPLFLALAAA
IDTGVIVINTERRIVFHNDTALHLLATQSPMQDSGLITLLRDHQADQLASDVLSDGEHRELTIRPIATGRTLHLHYVPLR
EGGGKPVGALITIRDLTQISMLERARRDLVANVSHELRTPLASLKLLVETVQSAPPPDIASRMLEQMAQEIDAVTQLVDE
LHELSRLESGRVSLKLEPLPVWPVIERAVERIRPQADRKQQVICVEPAADLPLALMDGDRIGQVLLNLLHNAVKFTPEGG
TITVAAEVLTLRDDEQPSRPDRPPHPAGTWLLIRVSDTGIGIPNRDIQRIFERFYKVDRARTRHAGGTGLGLAIAKHLVE
GHGGRIWASSQEGHGSTFWFTLPAA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=362, Percent_Identity=33.1491712707182, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=32.8185328185328, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=32.5102880658436, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=35.2697095435685, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI48994928, Length=295, Percent_Identity=30.5084745762712, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=33.0508474576271, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87081816, Length=243, Percent_Identity=31.2757201646091, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=32.7510917030568, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=32.0987654320988, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=307, Percent_Identity=28.0130293159609, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787894, Length=249, Percent_Identity=27.710843373494, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788713, Length=247, Percent_Identity=24.6963562753036, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786783, Length=254, Percent_Identity=27.9527559055118, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=246, Percent_Identity=32.1138211382114, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=243, Percent_Identity=31.2757201646091, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=234, Percent_Identity=25.2136752136752, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=240, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=256, Percent_Identity=25.390625, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=25.4166666666667, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46893; Mature: 46893

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLLEWMLMVATIALAVGFIVSMYRRHQKSHSSLVDHPSPPGTQEHSMISSARSETITSD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCC
SHLALLAIHRQPLFLALAAAIDTGVIVINTERRIVFHNDTALHLLATQSPMQDSGLITLL
CCEEEEEEECCCHHHHHHHHHCCCEEEEECCEEEEEECCCEEEEEEECCCCCCCCCEEEE
RDHQADQLASDVLSDGEHRELTIRPIATGRTLHLHYVPLREGGGKPVGALITIRDLTQIS
ECCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEECCCCCCEEEEEEEHHHHHHH
MLERARRDLVANVSHELRTPLASLKLLVETVQSAPPPDIASRMLEQMAQEIDAVTQLVDE
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LHELSRLESGRVSLKLEPLPVWPVIERAVERIRPQADRKQQVICVEPAADLPLALMDGDR
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEECCHH
IGQVLLNLLHNAVKFTPEGGTITVAAEVLTLRDDEQPSRPDRPPHPAGTWLLIRVSDTGI
HHHHHHHHHHHHHEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCC
GIPNRDIQRIFERFYKVDRARTRHAGGTGLGLAIAKHLVEGHGGRIWASSQEGHGSTFWF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEE
TLPAA
ECCCC
>Mature Secondary Structure
MMLLEWMLMVATIALAVGFIVSMYRRHQKSHSSLVDHPSPPGTQEHSMISSARSETITSD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCC
SHLALLAIHRQPLFLALAAAIDTGVIVINTERRIVFHNDTALHLLATQSPMQDSGLITLL
CCEEEEEEECCCHHHHHHHHHCCCEEEEECCEEEEEECCCEEEEEEECCCCCCCCCEEEE
RDHQADQLASDVLSDGEHRELTIRPIATGRTLHLHYVPLREGGGKPVGALITIRDLTQIS
ECCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEEECCCCCCEEEEEEEHHHHHHH
MLERARRDLVANVSHELRTPLASLKLLVETVQSAPPPDIASRMLEQMAQEIDAVTQLVDE
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LHELSRLESGRVSLKLEPLPVWPVIERAVERIRPQADRKQQVICVEPAADLPLALMDGDR
HHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEECCHH
IGQVLLNLLHNAVKFTPEGGTITVAAEVLTLRDDEQPSRPDRPPHPAGTWLLIRVSDTGI
HHHHHHHHHHHHHEECCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCC
GIPNRDIQRIFERFYKVDRARTRHAGGTGLGLAIAKHLVEGHGGRIWASSQEGHGSTFWF
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEE
TLPAA
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]