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The map label for this gene is baeS [H]

Identifier: 222525869

GI number: 222525869

Start: 3258870

End: 3260009

Strand: Reverse

Name: baeS [H]

Synonym: Chy400_2622

Alternate gene names: 222525869

Gene position: 3260009-3258870 (Counterclockwise)

Preceding gene: 222525870

Following gene: 222525858

Centisome position: 61.87

GC content: 56.75

Gene sequence:

>1140_bases
GTGAACGGTTGGCTGAAGCGTGGTGGATTACGCTACCGTCTGTTATTGTCCCATCTGCTGACCATTGCTGCCGGTGCGCT
AACTCTCTTGACGATCACAATCATCTTTGCCCCCGGCTTACACGATCAGTTGATGATCGCCTGGCTGGGGCCGCACTGGA
CTGAGACGGCTGACGCAAGTATGGTCGAGATGGAACGTGCAACCAATGCGATTTTTACGCTGGCTATGATACAGGCATTG
ACCATCAGCAGCGGCGCAGCCGTCACCGTCGCGATCATTGTGAGTCTGGTAGCTTCACGACAGATCGTACAGCCCATTGA
TCATCTGTTGCAGGTTACACGTCGCATAGCTGCCGGTCACTACGCTGAACGGGCACCGCTGATCGGAGATCGCGAACTGA
CACGCCTGGCTGCCCAGTTTAACATGATGGCTGAGGCCCTTGAACGTGCCGAACAGCGTCGTGTCGCCCTGATCGGTGAT
GTCGCGCACGAACTACGCACCCCTCTGGCGACCATTGCCGGCTATGTTGAGGGAATACTGGATGGCGTTGTTGAAACTGA
TGAGGCGACCTGGGCACTCGTTCTCGACGAAGTCAACCGTCTACGCCGATTAACCGATGATCTCCAGCAGCTATCGCGGG
TTGAGTCGCGCCAGATCACGCTCGCACCAACTCCGGTAGACCCGGCTCATCTCATTGAGGCTGCGGTAACGCGACTAACC
CCTCAGTTTACGGCCAAAAACATTGAGCTACACGTGAACATCGAGCAGCACCTGCCGCCGGTATGGGCAGATAGTGATCG
CATCCTGCAAGTTCTGATCAATCTCTTAGGCAATGCGTTGCAATACACACCGGGGGGCGGACGGGTTGTGATCGGGGCAG
AGCATGCAAGCGAGGCTATCCGCTTTTGGGTGCAGGACAGCGGAATTGGCATTGCCGCCGAACACCTGCCTCATCTGTTC
GAGCGCTTTTATCGGGTTGACAAGTCGCGTACTCGTGCGACCGGTGGCGCAGGCATTGGCCTCACCATTTGTAAGGGGTT
GGTTGAAATGCATGGTGGACAGATTTGGGCTACCAGTGCCGGGCCGGGGTGCGGTGCAACCTTTTACTTCACGCTCCCCC
TCTACGGACAACACGAGTAG

Upstream 100 bases:

>100_bases
TACATATTGCGAATTTACGCAAAAAATTGGGCGATGACCCGGCGCGCCCCCGCTTTATCTTTACCGTCCGGAGTGTTGGT
TATCGATTCGGAGAACGAAC

Downstream 100 bases:

>100_bases
AATCCAGATCGTTTCTTTTGAGCTATTTTGTTTGTGCCACAGGCAAGACAGCAGTAATAGGAAGACAATCTGATGAATCC
ACCCAGAGATACGCTGCCGG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNGWLKRGGLRYRLLLSHLLTIAAGALTLLTITIIFAPGLHDQLMIAWLGPHWTETADASMVEMERATNAIFTLAMIQAL
TISSGAAVTVAIIVSLVASRQIVQPIDHLLQVTRRIAAGHYAERAPLIGDRELTRLAAQFNMMAEALERAEQRRVALIGD
VAHELRTPLATIAGYVEGILDGVVETDEATWALVLDEVNRLRRLTDDLQQLSRVESRQITLAPTPVDPAHLIEAAVTRLT
PQFTAKNIELHVNIEQHLPPVWADSDRILQVLINLLGNALQYTPGGGRVVIGAEHASEAIRFWVQDSGIGIAAEHLPHLF
ERFYRVDKSRTRATGGAGIGLTICKGLVEMHGGQIWATSAGPGCGATFYFTLPLYGQHE

Sequences:

>Translated_379_residues
MNGWLKRGGLRYRLLLSHLLTIAAGALTLLTITIIFAPGLHDQLMIAWLGPHWTETADASMVEMERATNAIFTLAMIQAL
TISSGAAVTVAIIVSLVASRQIVQPIDHLLQVTRRIAAGHYAERAPLIGDRELTRLAAQFNMMAEALERAEQRRVALIGD
VAHELRTPLATIAGYVEGILDGVVETDEATWALVLDEVNRLRRLTDDLQQLSRVESRQITLAPTPVDPAHLIEAAVTRLT
PQFTAKNIELHVNIEQHLPPVWADSDRILQVLINLLGNALQYTPGGGRVVIGAEHASEAIRFWVQDSGIGIAAEHLPHLF
ERFYRVDKSRTRATGGAGIGLTICKGLVEMHGGQIWATSAGPGCGATFYFTLPLYGQHE
>Mature_379_residues
MNGWLKRGGLRYRLLLSHLLTIAAGALTLLTITIIFAPGLHDQLMIAWLGPHWTETADASMVEMERATNAIFTLAMIQAL
TISSGAAVTVAIIVSLVASRQIVQPIDHLLQVTRRIAAGHYAERAPLIGDRELTRLAAQFNMMAEALERAEQRRVALIGD
VAHELRTPLATIAGYVEGILDGVVETDEATWALVLDEVNRLRRLTDDLQQLSRVESRQITLAPTPVDPAHLIEAAVTRLT
PQFTAKNIELHVNIEQHLPPVWADSDRILQVLINLLGNALQYTPGGGRVVIGAEHASEAIRFWVQDSGIGIAAEHLPHLF
ERFYRVDKSRTRATGGAGIGLTICKGLVEMHGGQIWATSAGPGCGATFYFTLPLYGQHE

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=37.8181818181818, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1786783, Length=244, Percent_Identity=32.3770491803279, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=29.4820717131474, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786600, Length=287, Percent_Identity=29.616724738676, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=31.7596566523605, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081816, Length=235, Percent_Identity=31.063829787234, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789149, Length=333, Percent_Identity=26.7267267267267, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=31.8181818181818, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786912, Length=300, Percent_Identity=28, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787894, Length=270, Percent_Identity=30, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790346, Length=273, Percent_Identity=27.1062271062271, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=27.6595744680851, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=27.4261603375527, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790861, Length=234, Percent_Identity=32.0512820512821, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1788279, Length=307, Percent_Identity=27.3615635179153, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=295, Percent_Identity=23.728813559322, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790300, Length=270, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787374, Length=275, Percent_Identity=26.1818181818182, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41416; Mature: 41416

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGWLKRGGLRYRLLLSHLLTIAAGALTLLTITIIFAPGLHDQLMIAWLGPHWTETADAS
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHH
MVEMERATNAIFTLAMIQALTISSGAAVTVAIIVSLVASRQIVQPIDHLLQVTRRIAAGH
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YAERAPLIGDRELTRLAAQFNMMAEALERAEQRRVALIGDVAHELRTPLATIAGYVEGIL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGVVETDEATWALVLDEVNRLRRLTDDLQQLSRVESRQITLAPTPVDPAHLIEAAVTRLT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHCC
PQFTAKNIELHVNIEQHLPPVWADSDRILQVLINLLGNALQYTPGGGRVVIGAEHASEAI
CCCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEECHHHHHHH
RFWVQDSGIGIAAEHLPHLFERFYRVDKSRTRATGGAGIGLTICKGLVEMHGGQIWATSA
HHHEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECC
GPGCGATFYFTLPLYGQHE
CCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MNGWLKRGGLRYRLLLSHLLTIAAGALTLLTITIIFAPGLHDQLMIAWLGPHWTETADAS
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHH
MVEMERATNAIFTLAMIQALTISSGAAVTVAIIVSLVASRQIVQPIDHLLQVTRRIAAGH
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YAERAPLIGDRELTRLAAQFNMMAEALERAEQRRVALIGDVAHELRTPLATIAGYVEGIL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGVVETDEATWALVLDEVNRLRRLTDDLQQLSRVESRQITLAPTPVDPAHLIEAAVTRLT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHCC
PQFTAKNIELHVNIEQHLPPVWADSDRILQVLINLLGNALQYTPGGGRVVIGAEHASEAI
CCCCCCCEEEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEECHHHHHHH
RFWVQDSGIGIAAEHLPHLFERFYRVDKSRTRATGGAGIGLTICKGLVEMHGGQIWATSA
HHHEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEECC
GPGCGATFYFTLPLYGQHE
CCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]