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The map label for this gene is resD [H]

Identifier: 222525870

GI number: 222525870

Start: 3260006

End: 3260701

Strand: Reverse

Name: resD [H]

Synonym: Chy400_2623

Alternate gene names: 222525870

Gene position: 3260701-3260006 (Counterclockwise)

Preceding gene: 222525871

Following gene: 222525869

Centisome position: 61.89

GC content: 52.73

Gene sequence:

>696_bases
ATGCACACACCCCTGATCCTCATTGTTGATGACGAGAATCGGTTGCGCGAACTCATTCAGCGCTACCTTATTCAGGCTGG
GTTTCGCGTCGCCCATGCCGGCGATGGTTTGAGTGCCCTTGCCCAGGCCAGGACACTCCGCCCCGATCTGATCATCCTCG
ATCTGATGTTGCCGGCACTCGACGGTTTTGAGGTCTGTCGCCAGTTACGAACATTTTCTGATGCATACATCTTAATGCTG
ACCGCAAAAGTAGAGGAACCTGATCGCGTCAAAGGGTTGGAGGTTGGGGCTGATGATTATCTGGTGAAACCCTTTTCACC
ACGTGAATTAGTGGCCCGCGTGCGCGCCATGTTTCGGCGTCCCCGCCAATCGGGGTATATCGATGAACCCTCGACAATGA
CGGTTGGGCCACTCACTATCGATAGTGAATCGCATACTGTGCGGTTAGATGGAGTACCCATCAATCTGACCCCGTTAGAA
TATCGGCTGTTAACCATACTGGCTGCCGCTCCCGGACGAGTCTTCTCACGCGCCCAATTGCTTGATCAAGTTTGGGGAAA
CAATTACTTCGGCGATGAACACGTTCTGGAAGTACATATTGCGAATTTACGCAAAAAATTGGGCGATGACCCGGCGCGCC
CCCGCTTTATCTTTACCGTCCGGAGTGTTGGTTATCGATTCGGAGAACGAACGTGA

Upstream 100 bases:

>100_bases
CACACAGCGCAACAATTTGTTATGATGCTGGTAAGCCAATCTCTCTGCGCAAAGCGAGAGAACGTAACGTTGGGTCATTG
CATCATATCGCGGATTGACC

Downstream 100 bases:

>100_bases
ACGGTTGGCTGAAGCGTGGTGGATTACGCTACCGTCTGTTATTGTCCCATCTGCTGACCATTGCTGCCGGTGCGCTAACT
CTCTTGACGATCACAATCAT

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MHTPLILIVDDENRLRELIQRYLIQAGFRVAHAGDGLSALAQARTLRPDLIILDLMLPALDGFEVCRQLRTFSDAYILML
TAKVEEPDRVKGLEVGADDYLVKPFSPRELVARVRAMFRRPRQSGYIDEPSTMTVGPLTIDSESHTVRLDGVPINLTPLE
YRLLTILAAAPGRVFSRAQLLDQVWGNNYFGDEHVLEVHIANLRKKLGDDPARPRFIFTVRSVGYRFGERT

Sequences:

>Translated_231_residues
MHTPLILIVDDENRLRELIQRYLIQAGFRVAHAGDGLSALAQARTLRPDLIILDLMLPALDGFEVCRQLRTFSDAYILML
TAKVEEPDRVKGLEVGADDYLVKPFSPRELVARVRAMFRRPRQSGYIDEPSTMTVGPLTIDSESHTVRLDGVPINLTPLE
YRLLTILAAAPGRVFSRAQLLDQVWGNNYFGDEHVLEVHIANLRKKLGDDPARPRFIFTVRSVGYRFGERT
>Mature_231_residues
MHTPLILIVDDENRLRELIQRYLIQAGFRVAHAGDGLSALAQARTLRPDLIILDLMLPALDGFEVCRQLRTFSDAYILML
TAKVEEPDRVKGLEVGADDYLVKPFSPRELVARVRAMFRRPRQSGYIDEPSTMTVGPLTIDSESHTVRLDGVPINLTPLE
YRLLTILAAAPGRVFSRAQLLDQVWGNNYFGDEHVLEVHIANLRKKLGDDPARPRFIFTVRSVGYRFGERT

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=44.2477876106195, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=42.9824561403509, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=40.990990990991, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=39.6396396396396, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=39.5652173913043, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=39.647577092511, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=42.5339366515837, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=37.5, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=32.3275862068966, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.6283185840708, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787229, Length=211, Percent_Identity=35.0710900473934, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=37.7777777777778, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=32.4675324675325, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=32.2869955156951, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.0188679245283, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788222, Length=120, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=29.6610169491525, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=102, Percent_Identity=39.2156862745098, Blast_Score=60, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322000, Length=167, Percent_Identity=28.1437125748503, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26167; Mature: 26167

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTPLILIVDDENRLRELIQRYLIQAGFRVAHAGDGLSALAQARTLRPDLIILDLMLPAL
CCCCEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHCC
DGFEVCRQLRTFSDAYILMLTAKVEEPDRVKGLEVGADDYLVKPFSPRELVARVRAMFRR
CHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHC
PRQSGYIDEPSTMTVGPLTIDSESHTVRLDGVPINLTPLEYRLLTILAAAPGRVFSRAQL
CCCCCCCCCCCCEEECCEEECCCCCEEEECCEEEECCHHHHHHHHHHHCCCCHHHHHHHH
LDQVWGNNYFGDEHVLEVHIANLRKKLGDDPARPRFIFTVRSVGYRFGERT
HHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCCC
>Mature Secondary Structure
MHTPLILIVDDENRLRELIQRYLIQAGFRVAHAGDGLSALAQARTLRPDLIILDLMLPAL
CCCCEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHCC
DGFEVCRQLRTFSDAYILMLTAKVEEPDRVKGLEVGADDYLVKPFSPRELVARVRAMFRR
CHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHHC
PRQSGYIDEPSTMTVGPLTIDSESHTVRLDGVPINLTPLEYRLLTILAAAPGRVFSRAQL
CCCCCCCCCCCCEEECCEEECCCCCEEEECCEEEECCHHHHHHHHHHHCCCCHHHHHHHH
LDQVWGNNYFGDEHVLEVHIANLRKKLGDDPARPRFIFTVRSVGYRFGERT
HHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]