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The map label for this gene is ribH

Identifier: 222525622

GI number: 222525622

Start: 2996027

End: 2996494

Strand: Direct

Name: ribH

Synonym: Chy400_2373

Alternate gene names: 222525622

Gene position: 2996027-2996494 (Clockwise)

Preceding gene: 222525621

Following gene: 222525623

Centisome position: 56.86

GC content: 59.62

Gene sequence:

>468_bases
ATGACCATCTATGAAGGCACGTATATCGGCAGTGGCTTACGGATAGCGATTGTCGTCAGCCGCTGGAACGACCTGATTAC
CAACCGTCTGCTCGAAGGTGCGCGAGATGGACTGCTGCGGCATGGCGTAGCTGCGGATCATATCGACATTGCCTGGGTAC
CAGGCTCATTCGAGTTGCCGCTGGTATGCCATCGCCTGGCCGAGAGCAGTCGCTACGATGCAATCATTGCCCTCGGTGCC
GTGATTCGCGGTGCCACCACGCATCACGAGCACGTCGCTGCCGCTGCCAGCAGCGGGATTGCCCAGGTCAGCCTGCAAAC
CGGCGTCCCGTGTATCTTCGGCGTCATCACCACCGACAACATCGAGCAGGCTATCGAGCGCGCCGGTACCAAAGCCGGCA
ACAAAGGCTTTGAAGCGGCCACCGCCGCGATTGAGATGGCTACGCTGTTGCAGAGGCTAAATGGTTGA

Upstream 100 bases:

>100_bases
GCCGTGACGCAGGTTCCCATCTGTGGTACACCAAATCCGCACAACATTGCCTATCTGCTCACCAAACGGAATCGTCTAGG
ACATCAACTGGAGTGCATCT

Downstream 100 bases:

>100_bases
TGGTATCGAGTCCGGTTTAATATGAGTCATGGCAAGCCACCTGCCATCACCCTCACGCGGTGCCTTTAAGTGCTCCATCG
TGGCACGCAAGCGTCGGTAT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTIYEGTYIGSGLRIAIVVSRWNDLITNRLLEGARDGLLRHGVAADHIDIAWVPGSFELPLVCHRLAESSRYDAIIALGA
VIRGATTHHEHVAAAASSGIAQVSLQTGVPCIFGVITTDNIEQAIERAGTKAGNKGFEAATAAIEMATLLQRLNG

Sequences:

>Translated_155_residues
MTIYEGTYIGSGLRIAIVVSRWNDLITNRLLEGARDGLLRHGVAADHIDIAWVPGSFELPLVCHRLAESSRYDAIIALGA
VIRGATTHHEHVAAAASSGIAQVSLQTGVPCIFGVITTDNIEQAIERAGTKAGNKGFEAATAAIEMATLLQRLNG
>Mature_154_residues
TIYEGTYIGSGLRIAIVVSRWNDLITNRLLEGARDGLLRHGVAADHIDIAWVPGSFELPLVCHRLAESSRYDAIIALGAV
IRGATTHHEHVAAAASSGIAQVSLQTGVPCIFGVITTDNIEQAIERAGTKAGNKGFEAATAAIEMATLLQRLNG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=154, Percent_Identity=51.9480519480519, Blast_Score=159, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6324429, Length=149, Percent_Identity=33.5570469798658, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_CHLAA (A9WFR1)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001635800.1
- ProteinModelPortal:   A9WFR1
- SMR:   A9WFR1
- GeneID:   5826662
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_2202
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16401; Mature: 16270

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYEGTYIGSGLRIAIVVSRWNDLITNRLLEGARDGLLRHGVAADHIDIAWVPGSFELP
CEEECCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHH
LVCHRLAESSRYDAIIALGAVIRGATTHHEHVAAAASSGIAQVSLQTGVPCIFGVITTDN
HHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEECCCCCCEEEEEEECCC
IEQAIERAGTKAGNKGFEAATAAIEMATLLQRLNG
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIYEGTYIGSGLRIAIVVSRWNDLITNRLLEGARDGLLRHGVAADHIDIAWVPGSFELP
EEECCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHH
LVCHRLAESSRYDAIIALGAVIRGATTHHEHVAAAASSGIAQVSLQTGVPCIFGVITTDN
HHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEECCCCCCEEEEEEECCC
IEQAIERAGTKAGNKGFEAATAAIEMATLLQRLNG
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA