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The map label for this gene is argD [H]

Identifier: 222525349

GI number: 222525349

Start: 2663606

End: 2664808

Strand: Direct

Name: argD [H]

Synonym: Chy400_2094

Alternate gene names: 222525349

Gene position: 2663606-2664808 (Clockwise)

Preceding gene: 222525345

Following gene: 222525350

Centisome position: 50.55

GC content: 57.27

Gene sequence:

>1203_bases
ATGACCGGCGAACGCGCCGCAGAACTGATTCAAGCCGATCACCAATATCTGTTGCAGAGCTATGTACGCGCCGATTTCGT
CATTGAACGTGGCGAAGGGGTGTATCTTTACGATAGTGAAGGTCGGCGGTATCTCGATTTTGTCGCCGGCATTGCGGTGA
ATGCGCTTGGCTATGGTGATCGTGACGTTCTGAAAGCGATCAATGATCAGGCTGAACGCCTCATCCACGTTTCCAATCTC
TACCACACGCAACCGGCAATTGAACTGGCAAAGCTCCTGGTGCAGAGCAGCCCGGCGTTTGCCAAGGCGTTTTTCTGCAA
CAGTGGAGCTGAAGCGATTGAGGGGGCGATTAAGTTCTCACGTCGCTACGCTCGTGCCCATGTTGGCGAAGGCAAGACAA
CGATTGTTGCCTTCGACGGCAGTTTTCACGGGCGTACTATGGGAGCAGTTGCCATTACCGCCCGTGAAAAATACCGGGAG
CCGTTTATGCCGGTGATGCCCGGTGTGCGCTTTGCTCGCTACAACGACCTGGACTCACTGGCAGCCGTGATGGGCGATGA
TGTCTGTGCCGTGGTGGTTGAGCCGGTGCAGGGCGAGGGTGGCCTGCGTGCCGCTGAACCGGCCTTTATGCAGGGAGTGC
GCGAACTGTGCCAGCGCTATGGCGCATTGCTGGTCTTTGATGAAATTCAGTGCGGGGTTGGGCGTACCGGCACGCTCTGG
GCACACGAGCAGCTCGGTGTTCAGCCAGACATGATGACGGTAGCCAAACCGTTAGCCGGTGGGCTGCCGATTGGTGCGGT
GCTTATGGGCCAACACGTTGCCGATACCATTCATCCAGGCGACCATGGCACAACCTTTGGCGGTAATCCGCTGGCAACTG
CAGTTGGCACCGTCGTGTTCCGCAAAATTAGCGATCCGGCTTTCCTGGCCCATGTCCAGCAGGTAAGTAATTATCTCGAT
GAAGCGTTGCAGGATTTCGCTAATGAACACGCCGATCAGGTGATCGAATTGCGCGGACGTGGCCTGATGCGTGGTGTGCG
CATTGCCGGTTCTGCGAGTGCTGTACGTGAAGCGGCTCATCGCCATGGTCTGTTAGTCGCTACGGCTGGTGAAGATGTCA
TTCGCCTGCTCCCGCCCCTGATCATCGAGCCGCAGCACGTTGATGAGGCATTGTCTGGTCTGCGAGCGGCACTGCGCGCT
TGA

Upstream 100 bases:

>100_bases
CGAACGTTCAGCGACAACCGTCATTACCACAGCGACTCTGCTGCCGGTGGTATAATTGCGCCTGTGAACGTATCATCCAC
CGCGACGGAAAGGATATGCT

Downstream 100 bases:

>100_bases
TCAGAATGATCAGCGATCACGTTACCAGAGAATGTCGGGCGGAGTCGAAGAGGAAACGAGCCGGTGATCAGAATCTGACT
CGTAGCAGAATCAATCTTTC

Product: acetylornithine and succinylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTGERAAELIQADHQYLLQSYVRADFVIERGEGVYLYDSEGRRYLDFVAGIAVNALGYGDRDVLKAINDQAERLIHVSNL
YHTQPAIELAKLLVQSSPAFAKAFFCNSGAEAIEGAIKFSRRYARAHVGEGKTTIVAFDGSFHGRTMGAVAITAREKYRE
PFMPVMPGVRFARYNDLDSLAAVMGDDVCAVVVEPVQGEGGLRAAEPAFMQGVRELCQRYGALLVFDEIQCGVGRTGTLW
AHEQLGVQPDMMTVAKPLAGGLPIGAVLMGQHVADTIHPGDHGTTFGGNPLATAVGTVVFRKISDPAFLAHVQQVSNYLD
EALQDFANEHADQVIELRGRGLMRGVRIAGSASAVREAAHRHGLLVATAGEDVIRLLPPLIIEPQHVDEALSGLRAALRA

Sequences:

>Translated_400_residues
MTGERAAELIQADHQYLLQSYVRADFVIERGEGVYLYDSEGRRYLDFVAGIAVNALGYGDRDVLKAINDQAERLIHVSNL
YHTQPAIELAKLLVQSSPAFAKAFFCNSGAEAIEGAIKFSRRYARAHVGEGKTTIVAFDGSFHGRTMGAVAITAREKYRE
PFMPVMPGVRFARYNDLDSLAAVMGDDVCAVVVEPVQGEGGLRAAEPAFMQGVRELCQRYGALLVFDEIQCGVGRTGTLW
AHEQLGVQPDMMTVAKPLAGGLPIGAVLMGQHVADTIHPGDHGTTFGGNPLATAVGTVVFRKISDPAFLAHVQQVSNYLD
EALQDFANEHADQVIELRGRGLMRGVRIAGSASAVREAAHRHGLLVATAGEDVIRLLPPLIIEPQHVDEALSGLRAALRA
>Mature_399_residues
TGERAAELIQADHQYLLQSYVRADFVIERGEGVYLYDSEGRRYLDFVAGIAVNALGYGDRDVLKAINDQAERLIHVSNLY
HTQPAIELAKLLVQSSPAFAKAFFCNSGAEAIEGAIKFSRRYARAHVGEGKTTIVAFDGSFHGRTMGAVAITAREKYREP
FMPVMPGVRFARYNDLDSLAAVMGDDVCAVVVEPVQGEGGLRAAEPAFMQGVRELCQRYGALLVFDEIQCGVGRTGTLWA
HEQLGVQPDMMTVAKPLAGGLPIGAVLMGQHVADTIHPGDHGTTFGGNPLATAVGTVVFRKISDPAFLAHVQQVSNYLDE
ALQDFANEHADQVIELRGRGLMRGVRIAGSASAVREAAHRHGLLVATAGEDVIRLLPPLIIEPQHVDEALSGLRAALRA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=31.8877551020408, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI284507298, Length=293, Percent_Identity=35.1535836177474, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI13994255, Length=449, Percent_Identity=26.7260579064588, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=395, Percent_Identity=25.8227848101266, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI226442705, Length=395, Percent_Identity=25.8227848101266, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=25.7009345794392, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI226442709, Length=365, Percent_Identity=25.4794520547945, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI188536080, Length=450, Percent_Identity=23.3333333333333, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI38679950, Length=450, Percent_Identity=23.3333333333333, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI38679946, Length=450, Percent_Identity=23.3333333333333, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI1788044, Length=387, Percent_Identity=42.8940568475452, Blast_Score=320, Evalue=7e-89,
Organism=Escherichia coli, GI1789759, Length=381, Percent_Identity=41.4698162729659, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI145693181, Length=380, Percent_Identity=34.7368421052632, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789016, Length=394, Percent_Identity=33.756345177665, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1787560, Length=407, Percent_Identity=33.4152334152334, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786991, Length=413, Percent_Identity=29.0556900726392, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786349, Length=316, Percent_Identity=29.746835443038, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=29.923273657289, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=27.1689497716895, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=265, Percent_Identity=32.4528301886792, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=25.9953161592506, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=464, Percent_Identity=23.9224137931034, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71981843, Length=176, Percent_Identity=24.4318181818182, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=405, Percent_Identity=38.7654320987654, Blast_Score=309, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=30.5970149253731, Blast_Score=206, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6321456, Length=441, Percent_Identity=25.8503401360544, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324386, Length=351, Percent_Identity=25.3561253561254, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21357415, Length=402, Percent_Identity=30.0995024875622, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI161085790, Length=436, Percent_Identity=27.5229357798165, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28574759, Length=419, Percent_Identity=27.6849642004773, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21356575, Length=442, Percent_Identity=27.6018099547511, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281366494, Length=439, Percent_Identity=26.1958997722096, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24667139, Length=439, Percent_Identity=26.1958997722096, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24667143, Length=439, Percent_Identity=26.1958997722096, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43168; Mature: 43037

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGERAAELIQADHQYLLQSYVRADFVIERGEGVYLYDSEGRRYLDFVAGIAVNALGYGD
CCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
RDVLKAINDQAERLIHVSNLYHTQPAIELAKLLVQSSPAFAKAFFCNSGAEAIEGAIKFS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHH
RRYARAHVGEGKTTIVAFDGSFHGRTMGAVAITAREKYREPFMPVMPGVRFARYNDLDSL
HHHHHHHCCCCCEEEEEECCCCCCCEECCEEEEEHHHHCCCCCCCCCCCHHHHCCCHHHH
AAVMGDDVCAVVVEPVQGEGGLRAAEPAFMQGVRELCQRYGALLVFDEIQCGVGRTGTLW
HHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHCCCCCCCCEE
AHEQLGVQPDMMTVAKPLAGGLPIGAVLMGQHVADTIHPGDHGTTFGGNPLATAVGTVVF
EHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
RKISDPAFLAHVQQVSNYLDEALQDFANEHADQVIELRGRGLMRGVRIAGSASAVREAAH
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCHHHHHHHHH
RHGLLVATAGEDVIRLLPPLIIEPQHVDEALSGLRAALRA
HCCEEEEECCCHHHHHCCCHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGERAAELIQADHQYLLQSYVRADFVIERGEGVYLYDSEGRRYLDFVAGIAVNALGYGD
CHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
RDVLKAINDQAERLIHVSNLYHTQPAIELAKLLVQSSPAFAKAFFCNSGAEAIEGAIKFS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHH
RRYARAHVGEGKTTIVAFDGSFHGRTMGAVAITAREKYREPFMPVMPGVRFARYNDLDSL
HHHHHHHCCCCCEEEEEECCCCCCCEECCEEEEEHHHHCCCCCCCCCCCHHHHCCCHHHH
AAVMGDDVCAVVVEPVQGEGGLRAAEPAFMQGVRELCQRYGALLVFDEIQCGVGRTGTLW
HHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHCCCCCCCCEE
AHEQLGVQPDMMTVAKPLAGGLPIGAVLMGQHVADTIHPGDHGTTFGGNPLATAVGTVVF
EHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
RKISDPAFLAHVQQVSNYLDEALQDFANEHADQVIELRGRGLMRGVRIAGSASAVREAAH
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCHHHHHHHHH
RHGLLVATAGEDVIRLLPPLIIEPQHVDEALSGLRAALRA
HCCEEEEECCCHHHHHCCCHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]