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The map label for this gene is xylH [H]

Identifier: 222525336

GI number: 222525336

Start: 2646040

End: 2647254

Strand: Direct

Name: xylH [H]

Synonym: Chy400_2080

Alternate gene names: 222525336

Gene position: 2646040-2647254 (Clockwise)

Preceding gene: 222525335

Following gene: 222525337

Centisome position: 50.22

GC content: 53.0

Gene sequence:

>1215_bases
ATGGCTACCAGAACCCAAGTGAAACAGGCAACGTTTCTGGCTAATTTACAATACGTGCTGGGGCAGAATATCCGTCAATA
TGGTATGTTCATCGCCCTGTTCGTCATCATGATCATCTTTTCGATCACGACGAACGGTATCTTTATTTCGTCGCGTAATC
TGAGCAACCTGATCAACCAGACCGGTTATATTGCGGTGCTGGCGGTCGGGATGACGCTGGTGATCGTCATTCGCCATATC
GATCTGTCGGTCGGTTTTCTGGCCGGTTTTCTCGGTGCCGTCGCCGCAATTGCCCTGCGTTTTTGGGAATTACCCACCAT
CGTGGTCGTGCCCATGGTACTGGTGATGGGTGCTCTCGCCGGTTTGTTGACCGCTCTTCCGGTAGCTGAATTGAAGATTC
CGTCCTTCGTTGCTTCGCTGGCCGGCTGGCTGATCTACCGTGGCGCCTTGCAATTGGTGACTGCCGGTACCGGTACGATT
ATCATCGAAGACGAGACATTTAATGCGATTGGTAACGGTTTTATTCCTGATGTACCTTTCAGCCTGATACCCGGTTATCA
CACGCTGACCTTATTGCTGGGTGTAGTGGCAATTGTGGCTTACGTTTTGAGTGAGATCCGCACCCGGAACAAAAAGCTGG
CGTATAACTTCGAGGTGTTGCCCCTCGATATGTTTGTGCTCAAGCTGGTCTTCATCTCGACGCTGATCGGCTTACTGGCC
TGGATCATGGCCGGCTACAATGGCCTGTCGTGGACGATGGTCATTGTGCTGCTGGTGGTAGCAATTTATCACTTTGTGAC
GACGCAGACGGTGCTGGGACGGCATATCTATGCGGTTGGTGGTAACCCTGAAGCAGCTGAGTTGAGCGGGATCAGTGTCA
AGCGCATTACCTATATTGTGTTTGCTTCAATGGGTATGCTCGCAGCCCTATCGGGGGTGCTGTTTGCCTCGCGATTGCGC
TCGGCGACCACAACTGCCGGTACGCTCTTTGAGCTGGATGCGATTGCAGCCGCATATATCGGTGGTGTCTCGGCTGCCGG
TGGGGTTGGGAATGTGATTGGCTCGATCATCGGTGCTCTAGTGTACGTCTCGTTGACCAGCGGTATGAACCTGATGGGTA
TTGATATTGCGTATCAATACATCGTGCGTGGTCTGGTACTGGTGGCAGCGGTGATCTTCGACGTTACCACACGCCGGCGC
GGTCGTTCAGCGTGA

Upstream 100 bases:

>100_bases
TGGCAACCCAGGAAAAGATTATGGCCCTGGCAGTCGATTATTAACGGTATATCCTCAACGAGGAGTGATGATAGGTGTTA
CATCGAGGTAAGGAGTTGGC

Downstream 100 bases:

>100_bases
CGGTTGGCGATTGTTTCATCACTGGATGATGGTTCGGCGGTGCCGGACCTTGTGGTGCGCCAGCGAGGATGGGGCGGGTT
CACAACCCGCCCCATCCTTT

Product: inner-membrane translocator

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MATRTQVKQATFLANLQYVLGQNIRQYGMFIALFVIMIIFSITTNGIFISSRNLSNLINQTGYIAVLAVGMTLVIVIRHI
DLSVGFLAGFLGAVAAIALRFWELPTIVVVPMVLVMGALAGLLTALPVAELKIPSFVASLAGWLIYRGALQLVTAGTGTI
IIEDETFNAIGNGFIPDVPFSLIPGYHTLTLLLGVVAIVAYVLSEIRTRNKKLAYNFEVLPLDMFVLKLVFISTLIGLLA
WIMAGYNGLSWTMVIVLLVVAIYHFVTTQTVLGRHIYAVGGNPEAAELSGISVKRITYIVFASMGMLAALSGVLFASRLR
SATTTAGTLFELDAIAAAYIGGVSAAGGVGNVIGSIIGALVYVSLTSGMNLMGIDIAYQYIVRGLVLVAAVIFDVTTRRR
GRSA

Sequences:

>Translated_404_residues
MATRTQVKQATFLANLQYVLGQNIRQYGMFIALFVIMIIFSITTNGIFISSRNLSNLINQTGYIAVLAVGMTLVIVIRHI
DLSVGFLAGFLGAVAAIALRFWELPTIVVVPMVLVMGALAGLLTALPVAELKIPSFVASLAGWLIYRGALQLVTAGTGTI
IIEDETFNAIGNGFIPDVPFSLIPGYHTLTLLLGVVAIVAYVLSEIRTRNKKLAYNFEVLPLDMFVLKLVFISTLIGLLA
WIMAGYNGLSWTMVIVLLVVAIYHFVTTQTVLGRHIYAVGGNPEAAELSGISVKRITYIVFASMGMLAALSGVLFASRLR
SATTTAGTLFELDAIAAAYIGGVSAAGGVGNVIGSIIGALVYVSLTSGMNLMGIDIAYQYIVRGLVLVAAVIFDVTTRRR
GRSA
>Mature_403_residues
ATRTQVKQATFLANLQYVLGQNIRQYGMFIALFVIMIIFSITTNGIFISSRNLSNLINQTGYIAVLAVGMTLVIVIRHID
LSVGFLAGFLGAVAAIALRFWELPTIVVVPMVLVMGALAGLLTALPVAELKIPSFVASLAGWLIYRGALQLVTAGTGTII
IEDETFNAIGNGFIPDVPFSLIPGYHTLTLLLGVVAIVAYVLSEIRTRNKKLAYNFEVLPLDMFVLKLVFISTLIGLLAW
IMAGYNGLSWTMVIVLLVVAIYHFVTTQTVLGRHIYAVGGNPEAAELSGISVKRITYIVFASMGMLAALSGVLFASRLRS
ATTTAGTLFELDAIAAAYIGGVSAAGGVGNVIGSIIGALVYVSLTSGMNLMGIDIAYQYIVRGLVLVAAVIFDVTTRRRG
RSA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=381, Percent_Identity=38.5826771653543, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1790191, Length=371, Percent_Identity=34.2318059299191, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1788896, Length=166, Percent_Identity=36.144578313253, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI145693152, Length=153, Percent_Identity=37.9084967320261, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790524, Length=147, Percent_Identity=40.8163265306122, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787793, Length=352, Percent_Identity=28.125, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788471, Length=154, Percent_Identity=38.3116883116883, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082395, Length=120, Percent_Identity=39.1666666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787794, Length=153, Percent_Identity=28.1045751633987, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 43092; Mature: 42961

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRTQVKQATFLANLQYVLGQNIRQYGMFIALFVIMIIFSITTNGIFISSRNLSNLINQ
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHC
TGYIAVLAVGMTLVIVIRHIDLSVGFLAGFLGAVAAIALRFWELPTIVVVPMVLVMGALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GLLTALPVAELKIPSFVASLAGWLIYRGALQLVTAGTGTIIIEDETFNAIGNGFIPDVPF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHCCCCCCCCCH
SLIPGYHTLTLLLGVVAIVAYVLSEIRTRNKKLAYNFEVLPLDMFVLKLVFISTLIGLLA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
WIMAGYNGLSWTMVIVLLVVAIYHFVTTQTVLGRHIYAVGGNPEAAELSGISVKRITYIV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHCCCCHHHHHHHHH
FASMGMLAALSGVLFASRLRSATTTAGTLFELDAIAAAYIGGVSAAGGVGNVIGSIIGAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VYVSLTSGMNLMGIDIAYQYIVRGLVLVAAVIFDVTTRRRGRSA
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ATRTQVKQATFLANLQYVLGQNIRQYGMFIALFVIMIIFSITTNGIFISSRNLSNLINQ
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHC
TGYIAVLAVGMTLVIVIRHIDLSVGFLAGFLGAVAAIALRFWELPTIVVVPMVLVMGALA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GLLTALPVAELKIPSFVASLAGWLIYRGALQLVTAGTGTIIIEDETFNAIGNGFIPDVPF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHCCCCCCCCCH
SLIPGYHTLTLLLGVVAIVAYVLSEIRTRNKKLAYNFEVLPLDMFVLKLVFISTLIGLLA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
WIMAGYNGLSWTMVIVLLVVAIYHFVTTQTVLGRHIYAVGGNPEAAELSGISVKRITYIV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHCCCCHHHHHHHHH
FASMGMLAALSGVLFASRLRSATTTAGTLFELDAIAAAYIGGVSAAGGVGNVIGSIIGAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VYVSLTSGMNLMGIDIAYQYIVRGLVLVAAVIFDVTTRRRGRSA
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]