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The map label for this gene is nreC [H]

Identifier: 222525337

GI number: 222525337

Start: 2647635

End: 2648708

Strand: Direct

Name: nreC [H]

Synonym: Chy400_2081

Alternate gene names: 222525337

Gene position: 2647635-2648708 (Clockwise)

Preceding gene: 222525336

Following gene: 222525341

Centisome position: 50.25

GC content: 57.08

Gene sequence:

>1074_bases
ATGGGAACAACGCGCGTTGTAGTGGCCGATGATCACGCGGTGGTGCGCGCCGGATTGCGGAGCGCGCTGGCCAGTCTACC
GGAGTTTGAGGTGGTTGGCGAGGCGGCTGATGGGCCGCAATTACTGGCCGTGCTGGCGCAACACCAGCCCGATCTGCTGG
TCGTTGATGTCGCTATGCCTGATTTTGAGCCAATTGCCACGATTCGCCAGATTCACGCTACCTATCCGGCAATGAAGATT
CTGGTTGTCAGTGCCTATGACGATCAGTCCTATGTGGTCGGTCTGCTGGCGGCTGGTGTGAATGGCTATCACCTCAAGGA
TCAGCCCCTCAGCGATCTGCAACTGGCGGTGCAACGCATTATGGCCGGCGGGAACTGGATTTCCAGCCCTCTCCTGAGCC
GGATTATTCAGGCAGCACCTCAGATCACCCGCTCACCGCATATCACGCTGACCCGGCGCCAACGCGAACTCTTGCGCCTG
ATTGCCCAGGGTTACGACAACCGGCGGATGGCGCAAGAAATGGATCTGAGTGTCAAGACCATCGAGAACCATCTGACAGC
ACTCTACCGTGCTATTCACGTGAGTAGCCGGCTTGAGGCGTATCAATTCGCTATTCATCACCCTGAACTACTGGCTGAAA
CCGGTTACGAAGCGGCCCAGAACCGTGAGGCCGCAGGTAGCGGTGCCGCACCGTTGACCGTGCTGGTCGTTGACGATAAC
GAACGGTATCGTGCGCAATTGAAGCGGATGATCGGCAAAGCCTGTGGCGAAGCGCAGCTTTATGAGGCTGAAGATTGTCA
TCAGGCAGTGCGATTGCTTCAGCAGATCACGCCCGATCTGGTGTTTGTTGATGTTATTTTGAATGACGGTGACGGGATTC
AATGTCTGCGCCGCATCAAAACGACTCAGGCCGATGTGCGCGTGATCTTGATCAGTGCCTACCCTGATCGCGAGTTTCGC
CGTCTGGGTCTAGAGGCAGGCGCTCTGGCGTTTCTCGACAAAAAAGACCTCGACGCCGCTACGGTGCGCCAGGTAGTTGA
GGATGCGCTGCGCCGTAAGCGGAAAGTTCTCTAA

Upstream 100 bases:

>100_bases
ACAATCCTTTTTCGGGGATAATATCCTTTATCTCAATGAACAACTACTGGCAATGAAGCGGAGATAATTCCTGGGTTGGG
ATTGTAGTGAGGCATTGGCA

Downstream 100 bases:

>100_bases
ACCACCCCAATCCCTTCGGTTGTCGGGAAGGGTGCTGGATTGGGGATTTCAACCTGTAACTCTAATCCTCCCCATGCCGA
GGGGCCGATCCGCAGGGTGC

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MGTTRVVVADDHAVVRAGLRSALASLPEFEVVGEAADGPQLLAVLAQHQPDLLVVDVAMPDFEPIATIRQIHATYPAMKI
LVVSAYDDQSYVVGLLAAGVNGYHLKDQPLSDLQLAVQRIMAGGNWISSPLLSRIIQAAPQITRSPHITLTRRQRELLRL
IAQGYDNRRMAQEMDLSVKTIENHLTALYRAIHVSSRLEAYQFAIHHPELLAETGYEAAQNREAAGSGAAPLTVLVVDDN
ERYRAQLKRMIGKACGEAQLYEAEDCHQAVRLLQQITPDLVFVDVILNDGDGIQCLRRIKTTQADVRVILISAYPDREFR
RLGLEAGALAFLDKKDLDAATVRQVVEDALRRKRKVL

Sequences:

>Translated_357_residues
MGTTRVVVADDHAVVRAGLRSALASLPEFEVVGEAADGPQLLAVLAQHQPDLLVVDVAMPDFEPIATIRQIHATYPAMKI
LVVSAYDDQSYVVGLLAAGVNGYHLKDQPLSDLQLAVQRIMAGGNWISSPLLSRIIQAAPQITRSPHITLTRRQRELLRL
IAQGYDNRRMAQEMDLSVKTIENHLTALYRAIHVSSRLEAYQFAIHHPELLAETGYEAAQNREAAGSGAAPLTVLVVDDN
ERYRAQLKRMIGKACGEAQLYEAEDCHQAVRLLQQITPDLVFVDVILNDGDGIQCLRRIKTTQADVRVILISAYPDREFR
RLGLEAGALAFLDKKDLDAATVRQVVEDALRRKRKVL
>Mature_356_residues
GTTRVVVADDHAVVRAGLRSALASLPEFEVVGEAADGPQLLAVLAQHQPDLLVVDVAMPDFEPIATIRQIHATYPAMKIL
VVSAYDDQSYVVGLLAAGVNGYHLKDQPLSDLQLAVQRIMAGGNWISSPLLSRIIQAAPQITRSPHITLTRRQRELLRLI
AQGYDNRRMAQEMDLSVKTIENHLTALYRAIHVSSRLEAYQFAIHHPELLAETGYEAAQNREAAGSGAAPLTVLVVDDNE
RYRAQLKRMIGKACGEAQLYEAEDCHQAVRLLQQITPDLVFVDVILNDGDGIQCLRRIKTTQADVRVILISAYPDREFRR
LGLEAGALAFLDKKDLDAATVRQVVEDALRRKRKVL

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=212, Percent_Identity=25, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787473, Length=198, Percent_Identity=30.8080808080808, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=29, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786747, Length=204, Percent_Identity=25, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790102, Length=194, Percent_Identity=27.8350515463918, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788546, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788712, Length=199, Percent_Identity=23.6180904522613, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 39502; Mature: 39371

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTRVVVADDHAVVRAGLRSALASLPEFEVVGEAADGPQLLAVLAQHQPDLLVVDVAMP
CCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCC
DFEPIATIRQIHATYPAMKILVVSAYDDQSYVVGLLAAGVNGYHLKDQPLSDLQLAVQRI
CCHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
MAGGNWISSPLLSRIIQAAPQITRSPHITLTRRQRELLRLIAQGYDNRRMAQEMDLSVKT
HCCCCHHHHHHHHHHHHHCHHHCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHCCHHHH
IENHLTALYRAIHVSSRLEAYQFAIHHPELLAETGYEAAQNREAAGSGAAPLTVLVVDDN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHCCCCCCCCCCCEEEEEECCC
ERYRAQLKRMIGKACGEAQLYEAEDCHQAVRLLQQITPDLVFVDVILNDGDGIQCLRRIK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHH
TTQADVRVILISAYPDREFRRLGLEAGALAFLDKKDLDAATVRQVVEDALRRKRKVL
CCCCCEEEEEEECCCCHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GTTRVVVADDHAVVRAGLRSALASLPEFEVVGEAADGPQLLAVLAQHQPDLLVVDVAMP
CCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCC
DFEPIATIRQIHATYPAMKILVVSAYDDQSYVVGLLAAGVNGYHLKDQPLSDLQLAVQRI
CCHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
MAGGNWISSPLLSRIIQAAPQITRSPHITLTRRQRELLRLIAQGYDNRRMAQEMDLSVKT
HCCCCHHHHHHHHHHHHHCHHHCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHCCHHHH
IENHLTALYRAIHVSSRLEAYQFAIHHPELLAETGYEAAQNREAAGSGAAPLTVLVVDDN
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHCCCCCCCCCCCEEEEEECCC
ERYRAQLKRMIGKACGEAQLYEAEDCHQAVRLLQQITPDLVFVDVILNDGDGIQCLRRIK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHH
TTQADVRVILISAYPDREFRRLGLEAGALAFLDKKDLDAATVRQVVEDALRRKRKVL
CCCCCEEEEEEECCCCHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]