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The map label for this gene is potC [H]

Identifier: 222525087

GI number: 222525087

Start: 2306972

End: 2307838

Strand: Direct

Name: potC [H]

Synonym: Chy400_1824

Alternate gene names: 222525087

Gene position: 2306972-2307838 (Clockwise)

Preceding gene: 222525086

Following gene: 222525088

Centisome position: 43.78

GC content: 55.13

Gene sequence:

>867_bases
ATGATCAAGACAGCACCCGCTTCAACCACGCTGACCCGCGCCCGTGGTGCGTTTGCTGAGGGGCGCCTGACGTGGAGCGG
TGTGGGATTGACGATCTTCTCAATCCTGGTCTATCTGTTCCTGTATGCGCCGATTGTCATTCTGGTCATCTTTTCCTTTA
CCCGCGATGAGTTTGGTGTGCGTTGGACAGGCTTTACACTTGACTGGTATATCCGCCTGTTCAACAATCCACGTATGATG
GGGGCCGCCTGGAATACGTTAGTCGTGGCCAGTGTGTCAACGGTTGTGTCAACGATCATCGGTACCTTGCTGGCGATGGC
GATGGAGCGCTATCGGTTTCAGGGGCGGGGAGCGATGGAAGGGTTGATTTATCTCCCGATTGTGGTGCCCGAAATCGTGA
TGGCGGTCGCTCTGCTGGCGTTCTCGGCAATTGCCTTTGACCTGATCAAAATGGTGACCGGTGAGACGCTGCGGCGTAAT
CTCACCACGGTGACGATTGGCCACATCGCCTTCAGCATCTCGTTTGTCGTGGTTGTTGTGCGTACCAGCCTCAAAAATTT
CGACCGTCGGCTCGAAGAAGCAGCAGCCGATTTAGGGGCCGACAACTGGAACATTTTCTGGCGCATTACCTTTCCGCTGA
TCTTGCCCGGTATCGTGGGTGGTGCTTTGCTGGCCTTTACCCTCTCGCTCGACGACTTCATCATTTCGCTGTTCCTCTCC
GGGCCGGGAACTTCCCTCCTACCGGTGGAAGTGTATAACCGTGTGCGACGAGCAGTGACGCCAGAAATTAACGCTATTTC
TACCCTGATGCTGCTGTTGTCGATGGTGCTGGTCGCACTGTCGCAACTTTTGCAGCGACGACGATAG

Upstream 100 bases:

>100_bases
CGATTAACTGGCCACTCGGCTCAGCAATGGCTGTGCTGATGATGATCGTGCTGCTGGTGCTGATTATGATGTACTTCCGC
GCAACAACGGAGGAAGAGCG

Downstream 100 bases:

>100_bases
GTCTGGATACACAGTAGTGAGGGAGGTTGAGAATGCAGATGCTTCGATTGCTGGTGCTGGTGCTGCTTCTGATACTAACG
GCGTGTGGTGGCGGTGGTGC

Product: Ornithine carbamoyltransferase

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MIKTAPASTTLTRARGAFAEGRLTWSGVGLTIFSILVYLFLYAPIVILVIFSFTRDEFGVRWTGFTLDWYIRLFNNPRMM
GAAWNTLVVASVSTVVSTIIGTLLAMAMERYRFQGRGAMEGLIYLPIVVPEIVMAVALLAFSAIAFDLIKMVTGETLRRN
LTTVTIGHIAFSISFVVVVVRTSLKNFDRRLEEAAADLGADNWNIFWRITFPLILPGIVGGALLAFTLSLDDFIISLFLS
GPGTSLLPVEVYNRVRRAVTPEINAISTLMLLLSMVLVALSQLLQRRR

Sequences:

>Translated_288_residues
MIKTAPASTTLTRARGAFAEGRLTWSGVGLTIFSILVYLFLYAPIVILVIFSFTRDEFGVRWTGFTLDWYIRLFNNPRMM
GAAWNTLVVASVSTVVSTIIGTLLAMAMERYRFQGRGAMEGLIYLPIVVPEIVMAVALLAFSAIAFDLIKMVTGETLRRN
LTTVTIGHIAFSISFVVVVVRTSLKNFDRRLEEAAADLGADNWNIFWRITFPLILPGIVGGALLAFTLSLDDFIISLFLS
GPGTSLLPVEVYNRVRRAVTPEINAISTLMLLLSMVLVALSQLLQRRR
>Mature_288_residues
MIKTAPASTTLTRARGAFAEGRLTWSGVGLTIFSILVYLFLYAPIVILVIFSFTRDEFGVRWTGFTLDWYIRLFNNPRMM
GAAWNTLVVASVSTVVSTIIGTLLAMAMERYRFQGRGAMEGLIYLPIVVPEIVMAVALLAFSAIAFDLIKMVTGETLRRN
LTTVTIGHIAFSISFVVVVVRTSLKNFDRRLEEAAADLGADNWNIFWRITFPLILPGIVGGALLAFTLSLDDFIISLFLS
GPGTSLLPVEVYNRVRRAVTPEINAISTLMLLLSMVLVALSQLLQRRR

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=237, Percent_Identity=40.5063291139241, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1787081, Length=238, Percent_Identity=39.0756302521008, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1788764, Length=229, Percent_Identity=31.4410480349345, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787714, Length=239, Percent_Identity=30.5439330543933, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787369, Length=211, Percent_Identity=28.436018957346, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787713, Length=195, Percent_Identity=29.7435897435897, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786980, Length=118, Percent_Identity=35.5932203389831, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31903; Mature: 31903

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTAPASTTLTRARGAFAEGRLTWSGVGLTIFSILVYLFLYAPIVILVIFSFTRDEFGV
CCCCCCCCHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RWTGFTLDWYIRLFNNPRMMGAAWNTLVVASVSTVVSTIIGTLLAMAMERYRFQGRGAME
EEECCHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLIYLPIVVPEIVMAVALLAFSAIAFDLIKMVTGETLRRNLTTVTIGHIAFSISFVVVVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHH
RTSLKNFDRRLEEAAADLGADNWNIFWRITFPLILPGIVGGALLAFTLSLDDFIISLFLS
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPGTSLLPVEVYNRVRRAVTPEINAISTLMLLLSMVLVALSQLLQRRR
CCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKTAPASTTLTRARGAFAEGRLTWSGVGLTIFSILVYLFLYAPIVILVIFSFTRDEFGV
CCCCCCCCHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RWTGFTLDWYIRLFNNPRMMGAAWNTLVVASVSTVVSTIIGTLLAMAMERYRFQGRGAME
EEECCHHHHHHHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GLIYLPIVVPEIVMAVALLAFSAIAFDLIKMVTGETLRRNLTTVTIGHIAFSISFVVVVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHH
RTSLKNFDRRLEEAAADLGADNWNIFWRITFPLILPGIVGGALLAFTLSLDDFIISLFLS
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GPGTSLLPVEVYNRVRRAVTPEINAISTLMLLLSMVLVALSQLLQRRR
CCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]