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The map label for this gene is srlE [H]

Identifier: 222524725

GI number: 222524725

Start: 1838887

End: 1839420

Strand: Reverse

Name: srlE [H]

Synonym: Chy400_1452

Alternate gene names: 222524725

Gene position: 1839420-1838887 (Counterclockwise)

Preceding gene: 222524726

Following gene: 222524724

Centisome position: 34.91

GC content: 49.63

Gene sequence:

>534_bases
ATGGAGGGTATAACAAAGCTGTTAGAGCGCATCGGTCGCGGAGCGGGAAAAGTAGTCGGTGTGCTCTACCAATCAGGGCG
AGAAGCTATCGATCAGGTTGTGAAAAATATCCTGCCCTTCATGGCATTTATCTCTTTCATTATCGGTGTTATTCTCGCCA
CCGGCATTGGCGATATTTTGGCGCGAGCCTTGCAACCACTGGCTACAAATCCTGTAGGCCTGGTTATTATGTCACTTATA
ATCGGTTTGCCGGTACTATCGCCACTTCTCGGTCCAGGTGCCGTGATTGCCCAGATTATAGGCACGTTATTAGGAACTCA
GTTTGCCAGCCAGGCACTCCCGGCATATGTTGCCTTGCCTGCTTTATTTGCTATCAACCCACAAGTAGGATGCGATTTTA
TCCCTGTTGGTCTGGCATTAGGTGAAGCTGAGCCTGAGACGGTCGAAGTTGGGGTGCCGGCAGTACTGTTCTCTCGACTT
ATTACCGGTCCTATTGCTGTCATCATCGCTTGGATCTTCAGCGTTGGTCTTTGA

Upstream 100 bases:

>100_bases
TTGGCTTAATTGTCATCTTCATTCGTGGTCTTGTTACTGAGCGAATAACTGCATTCCTGTTGGCACGACGTGTAGCCTAT
GCGGCTTAGGAGGTAAGGCG

Downstream 100 bases:

>100_bases
TCTTTGAAGGGTATGAAGCAACTTTGTCTCAAGCTTCATACCCGAATCAAATCAAGAAAGGAGGATATGTCTATGACTGA
GGTGAAAAAGTACCGCAAGG

Product: Protein-N(pi)-phosphohistidine--sugar phosphotransferase

Products: NA

Alternate protein names: EII-Gut; PTS system glucitol/sorbitol-specific EIIB component [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MEGITKLLERIGRGAGKVVGVLYQSGREAIDQVVKNILPFMAFISFIIGVILATGIGDILARALQPLATNPVGLVIMSLI
IGLPVLSPLLGPGAVIAQIIGTLLGTQFASQALPAYVALPALFAINPQVGCDFIPVGLALGEAEPETVEVGVPAVLFSRL
ITGPIAVIIAWIFSVGL

Sequences:

>Translated_177_residues
MEGITKLLERIGRGAGKVVGVLYQSGREAIDQVVKNILPFMAFISFIIGVILATGIGDILARALQPLATNPVGLVIMSLI
IGLPVLSPLLGPGAVIAQIIGTLLGTQFASQALPAYVALPALFAINPQVGCDFIPVGLALGEAEPETVEVGVPAVLFSRL
ITGPIAVIIAWIFSVGL
>Mature_177_residues
MEGITKLLERIGRGAGKVVGVLYQSGREAIDQVVKNILPFMAFISFIIGVILATGIGDILARALQPLATNPVGLVIMSLI
IGLPVLSPLLGPGAVIAQIIGTLLGTQFASQALPAYVALPALFAINPQVGCDFIPVGLALGEAEPETVEVGVPAVLFSRL
ITGPIAVIIAWIFSVGL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3732

COG function: function code G; Phosphotransferase system sorbitol-specific component IIBC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994905, Length=168, Percent_Identity=58.9285714285714, Blast_Score=198, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011638
- InterPro:   IPR011618
- InterPro:   IPR004702 [H]

Pfam domain/function: PF07663 EIIBC-GUT_C; PF03612 EIIBC-GUT_N [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 18260; Mature: 18260

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS51102 PTS_EIIB_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGITKLLERIGRGAGKVVGVLYQSGREAIDQVVKNILPFMAFISFIIGVILATGIGDIL
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARALQPLATNPVGLVIMSLIIGLPVLSPLLGPGAVIAQIIGTLLGTQFASQALPAYVALP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFAINPQVGCDFIPVGLALGEAEPETVEVGVPAVLFSRLITGPIAVIIAWIFSVGL
HHHHCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEGITKLLERIGRGAGKVVGVLYQSGREAIDQVVKNILPFMAFISFIIGVILATGIGDIL
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARALQPLATNPVGLVIMSLIIGLPVLSPLLGPGAVIAQIIGTLLGTQFASQALPAYVALP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFAINPQVGCDFIPVGLALGEAEPETVEVGVPAVLFSRLITGPIAVIIAWIFSVGL
HHHHCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]