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The map label for this gene is srlA [H]

Identifier: 222524726

GI number: 222524726

Start: 1839432

End: 1839980

Strand: Reverse

Name: srlA [H]

Synonym: Chy400_1453

Alternate gene names: 222524726

Gene position: 1839980-1839432 (Counterclockwise)

Preceding gene: 222524727

Following gene: 222524725

Centisome position: 34.92

GC content: 49.18

Gene sequence:

>549_bases
ATGGAATTTTTAGTTGATGCCGCTGTATGGTTCATCGGCTTATTCCAGAAGGGCGCTGAGACGTTCGTCGGACTGGTAAC
CGGTATTGTTCCACTTGTCATTGTACTACTGACAGCCTTCAATGCTCTGGTTGCACTTATCGGCCAGGAGCGGATCGATA
AGATTGGAGAGGCAGCCGGCAAAGAGGGTTTTCTGTACACCCCATTACGTTATTTGGTCTTACCGGTTGTATCCGTCTTC
GTTCTCACCAATCCGATGGCATACACAATGGGACGCTTCCTGCCCGAGCGCTACAAACCAGCGTTCTACGATGCAGCAGT
ATCTTTCGTTCATCCCCCACTTGGTATTTTTCCTCACGTGAATCCAGGCGAGTTATTTGTGTGGGCAGGTATTGCCCAAG
GTATAACTGCTGGCTACGGCAGTGAAGAAACAGCGGCACTGGCAGTACGTTATCTGATAGTTGGCTTAATTGTCATCTTC
ATTCGTGGTCTTGTTACTGAGCGAATAACTGCATTCCTGTTGGCACGACGTGTAGCCTATGCGGCTTAG

Upstream 100 bases:

>100_bases
TCTTTGCGGAATTGAGCTGAAAGGAGGTCATACAAGTCGAAAGTGTGCGCAGGGTCTGGGAGTGGTCTAATCGTAGCTTA
GTTATTCAGGGAGGTAGGCA

Downstream 100 bases:

>100_bases
GAGGTAAGGCGATGGAGGGTATAACAAAGCTGTTAGAGCGCATCGGTCGCGGAGCGGGAAAAGTAGTCGGTGTGCTCTAC
CAATCAGGGCGAGAAGCTAT

Product: PTS system, glucitol/sorbitol-specific, IIC subunit

Products: D-sorbitol 6-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gut; PTS system glucitol/sorbitol-specific EIIC component [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MEFLVDAAVWFIGLFQKGAETFVGLVTGIVPLVIVLLTAFNALVALIGQERIDKIGEAAGKEGFLYTPLRYLVLPVVSVF
VLTNPMAYTMGRFLPERYKPAFYDAAVSFVHPPLGIFPHVNPGELFVWAGIAQGITAGYGSEETAALAVRYLIVGLIVIF
IRGLVTERITAFLLARRVAYAA

Sequences:

>Translated_182_residues
MEFLVDAAVWFIGLFQKGAETFVGLVTGIVPLVIVLLTAFNALVALIGQERIDKIGEAAGKEGFLYTPLRYLVLPVVSVF
VLTNPMAYTMGRFLPERYKPAFYDAAVSFVHPPLGIFPHVNPGELFVWAGIAQGITAGYGSEETAALAVRYLIVGLIVIF
IRGLVTERITAFLLARRVAYAA
>Mature_182_residues
MEFLVDAAVWFIGLFQKGAETFVGLVTGIVPLVIVLLTAFNALVALIGQERIDKIGEAAGKEGFLYTPLRYLVLPVVSVF
VLTNPMAYTMGRFLPERYKPAFYDAAVSFVHPPLGIFPHVNPGELFVWAGIAQGITAGYGSEETAALAVRYLIVGLIVIF
IRGLVTERITAFLLARRVAYAA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3730

COG function: function code G; Phosphotransferase system sorbitol-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994904, Length=172, Percent_Identity=49.4186046511628, Blast_Score=166, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004699 [H]

Pfam domain/function: PF03608 EII-GUT [H]

EC number: NA

Molecular weight: Translated: 19809; Mature: 19809

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS51107 PTS_EIIC_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLVDAAVWFIGLFQKGAETFVGLVTGIVPLVIVLLTAFNALVALIGQERIDKIGEAAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KEGFLYTPLRYLVLPVVSVFVLTNPMAYTMGRFLPERYKPAFYDAAVSFVHPPLGIFPHV
CCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
NPGELFVWAGIAQGITAGYGSEETAALAVRYLIVGLIVIFIRGLVTERITAFLLARRVAY
CCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AA
CC
>Mature Secondary Structure
MEFLVDAAVWFIGLFQKGAETFVGLVTGIVPLVIVLLTAFNALVALIGQERIDKIGEAAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KEGFLYTPLRYLVLPVVSVFVLTNPMAYTMGRFLPERYKPAFYDAAVSFVHPPLGIFPHV
CCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
NPGELFVWAGIAQGITAGYGSEETAALAVRYLIVGLIVIFIRGLVTERITAFLLARRVAY
CCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; sorbitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + sorbitol [Periplasm] = D-sorbitol 6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]