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The map label for this gene is rsbRA [H]

Identifier: 222524703

GI number: 222524703

Start: 1816938

End: 1817783

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_1430

Alternate gene names: 222524703

Gene position: 1817783-1816938 (Counterclockwise)

Preceding gene: 222524704

Following gene: 222524702

Centisome position: 34.5

GC content: 54.85

Gene sequence:

>846_bases
ATGAGCGCCATCCTGAGCAGCCTGGCTGCATTCATTCGTGAACGGTTACCGCAGACAGGTGCGCGTTTGCTGCACGCTGT
ACAGAGCAGTAGTAGCGGATATGCCTCAATCCCGGCTGACGAACTCCGCCCCGCCCTGCAACGTTCGGTTGAGACGATCT
GTGCTGTCTTTGGTGACAATAATGCAGGCCCGCTGAACGAATGGGCACCCTACATCGGTGAGCGACGCGCCCGGATGGGC
CTGTCGCTCGACGATATGATGAGCGTCGTCTCAGGTATCCGTGAGTTTTGCTGGCAGGAGTTAACCGAATTCGGCAGTGA
TCGTCTAACCATCGGTGATGTCCGTCAATTTGAAGATGCCATCAGTGAATTTAACCGCTTGCTGTTGTTGGGCTACAGTC
AGGCAATGCTGACCCTCCAGCAAGAGTTGCATGATCAGGCCGAACAGATTGCTGCGCAGCAGCAGACTATCCGCGAGCTG
AGCACACCTATTCTACCGCTCTACGAAGGGATTCTTGTCTTGCCACTGGTTGGCGCAATTGACAGTTTCCGCGCCGGCCA
GATTATGGAACGTCTGCTAACAGCCATTGCTGAACGTCAGTCAGATATTGTGATTATTGATATTACCGGGGTGCCGGTGA
TCGATACTGCGGTCGCCAACTATCTCTTGCAGACGGCGCGGGCGGCGCAGTTGATCGGTGCCCAGGTGATTCTGGTCGGT
ATTGGCCCGGAAATTGCTCAGACGATTGTGCAACTGGGTGTTGATCTGCGTGGAATCCAGATCGGCGCCAATCTTCAGGC
CGGCATTGAACTGGCATTAAGTCAGCAAGGCTACACCATTCGCTGA

Upstream 100 bases:

>100_bases
GTCGGTCGGTCGCTGTGTTTACACCGGTCGCGAAACGGATCGTCAGGTAATCTTTGCCCGTGCCTATTGATGCGGTATCT
GTTTAGTGTCGGAGAATACC

Downstream 100 bases:

>100_bases
TCAGGTGAGGTACTGATGCCCCAGGTCATTGCTAACATCGTCGCCTTCTGCGAGGCACGCCTGGTCGAAACTGCTGAACG
GTTTACCGATGAGCTTCGTA

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSAILSSLAAFIRERLPQTGARLLHAVQSSSSGYASIPADELRPALQRSVETICAVFGDNNAGPLNEWAPYIGERRARMG
LSLDDMMSVVSGIREFCWQELTEFGSDRLTIGDVRQFEDAISEFNRLLLLGYSQAMLTLQQELHDQAEQIAAQQQTIREL
STPILPLYEGILVLPLVGAIDSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQTARAAQLIGAQVILVG
IGPEIAQTIVQLGVDLRGIQIGANLQAGIELALSQQGYTIR

Sequences:

>Translated_281_residues
MSAILSSLAAFIRERLPQTGARLLHAVQSSSSGYASIPADELRPALQRSVETICAVFGDNNAGPLNEWAPYIGERRARMG
LSLDDMMSVVSGIREFCWQELTEFGSDRLTIGDVRQFEDAISEFNRLLLLGYSQAMLTLQQELHDQAEQIAAQQQTIREL
STPILPLYEGILVLPLVGAIDSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQTARAAQLIGAQVILVG
IGPEIAQTIVQLGVDLRGIQIGANLQAGIELALSQQGYTIR
>Mature_280_residues
SAILSSLAAFIRERLPQTGARLLHAVQSSSSGYASIPADELRPALQRSVETICAVFGDNNAGPLNEWAPYIGERRARMGL
SLDDMMSVVSGIREFCWQELTEFGSDRLTIGDVRQFEDAISEFNRLLLLGYSQAMLTLQQELHDQAEQIAAQQQTIRELS
TPILPLYEGILVLPLVGAIDSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQTARAAQLIGAQVILVGI
GPEIAQTIVQLGVDLRGIQIGANLQAGIELALSQQGYTIR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 30556; Mature: 30424

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAILSSLAAFIRERLPQTGARLLHAVQSSSSGYASIPADELRPALQRSVETICAVFGDN
CHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
NAGPLNEWAPYIGERRARMGLSLDDMMSVVSGIREFCWQELTEFGSDRLTIGDVRQFEDA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
ISEFNRLLLLGYSQAMLTLQQELHDQAEQIAAQQQTIRELSTPILPLYEGILVLPLVGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQTARAAQLIGAQVILVG
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEE
IGPEIAQTIVQLGVDLRGIQIGANLQAGIELALSQQGYTIR
CCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAILSSLAAFIRERLPQTGARLLHAVQSSSSGYASIPADELRPALQRSVETICAVFGDN
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
NAGPLNEWAPYIGERRARMGLSLDDMMSVVSGIREFCWQELTEFGSDRLTIGDVRQFEDA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
ISEFNRLLLLGYSQAMLTLQQELHDQAEQIAAQQQTIRELSTPILPLYEGILVLPLVGAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
DSFRAGQIMERLLTAIAERQSDIVIIDITGVPVIDTAVANYLLQTARAAQLIGAQVILVG
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEE
IGPEIAQTIVQLGVDLRGIQIGANLQAGIELALSQQGYTIR
CCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]